Crinum macowanii - Unknown
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Internal ID UUID644025bb5b13d580903063
Scientific name Crinum macowanii
Authority Baker
First published in Gard. Chron. , n.s., 9: 298 (1878)

Description Top

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Crinum macowanii is a deciduous bulbous plant species found in Africa that has been used in traditional medicine for various ailments. It is known by different names among different African cultures and is named after the British botanist Peter MacOwan. The plant has long, slender, bell-shaped flowers that are highly scented and vary in size. It is native to most of east, central, and southern Africa and is found in various habitats. However, its existence is threatened due to unsustainable harvesting for medicinal purposes. The plant has been traditionally used for back pain, swelling, urinary tract disorders, and other conditions. Scientific research has found that it has antiviral and weak anti-fungal properties. The plant contains alkaloids, including lycorine, which is also found in the roots and leaves. Galantamine, a compound with potential medicinal uses, has also been isolated from the plant.

Synonyms Top

Scientific name Authority First published in
Crinum corradii Chiov. apud Chiartigi Webbia 8: 6. 1951
Crinum gouwsii Traub Pl. Life 10: 40 (1954)
Crinum johnstonii Baker Bot. Mag. 128: t. 7812 (1902)
Crinum pedicellatum Pax Bot. Jahrb. Syst. 15: 142 (1892)
Crinum macowanii subsp. confusum I.Verd. J. S. African Bot. 32: 67. 1966 (1966)
Crinum macowanii subsp. kalahariense L.S.Hannibal Bull. Louisiana Soc. Hort. Res. 3(5): 256 (1972)

Common names Top

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Language Common/alternative name
English pyjama lily
Russian Кринум Макована

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • East Tropical Africa
      • Kenya
      • Tanzania
      • Uganda
    • Northeast Tropical Africa
      • Eritrea
      • Ethiopia
      • Somalia
      • Sudan
    • South Tropical Africa
      • Angola
      • Malawi
      • Mozambique
      • Zambia
      • Zimbabwe
    • Southern Africa
      • Botswana
      • Cape Provinces
      • Free State
      • Kwazulu-Natal
      • Namibia
      • Northern Provinces
      • Swaziland
    • West-central Tropical Africa
      • Zaïre
    • Western Indian Ocean
      • Seychelles

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000764586
USDA Plants CRMA23
Tropicos 1200097
KEW urn:lsid:ipni.org:names:63973-1
The Plant List kew-303499
Open Tree Of Life 826238
NCBI Taxonomy 180140
IPNI 63973-1
iNaturalist 429305
GBIF 2853929
EOL 1087203
USDA GRIN 12228
Wikipedia Crinum_macowanii

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
The anticancer and antibacterial potential of bioactive secondary metabolites derived From bacterial endophytes in association with Artemisia absinthium Damavandi MS, Shojaei H, Esfahani BN Sci Rep 27-Oct-2023
PMCID:PMC10611800
doi:10.1038/s41598-023-45910-w
PMID:37891400
Benzoindolizidine Alkaloids Tylophorine and Lycorine and Their Analogues with Antiviral, Anti-Inflammatory, and Anticancer Properties: Promises and Challenges Di Sotto A, Valipour M, Azari A, Di Giacomo S, Irannejad H Biomedicines 24-Sep-2023
PMCID:PMC10603990
doi:10.3390/biomedicines11102619
PMID:37892993
Important Medicinal and Food Taxa (Orders and Families) in Kenya, Based on Three Quantitative Approaches Mutie FM, Mbuni YM, Rono PC, Mkala EM, Nzei JM, Phumthum M, Hu GW, Wang QF Plants (Basel) 02-Mar-2023
PMCID:PMC10005506
doi:10.3390/plants12051145
PMID:36904005
Sustainable Applications of Endophytic Bacteria and Their Physiological/Biochemical Roles on Medicinal and Herbal Plants: Review Tshikhudo PP, Ntushelo K, Mudau FN Microorganisms 10-Feb-2023
PMCID:PMC9967847
doi:10.3390/microorganisms11020453
PMID:36838418
Antileishmanial Activity of Clinanthus milagroanthus S. Leiva & Meerow (Amaryllidaceae) Collected in Peru Soto-Vásquez MR, Alvarado-García PA, Osorio EH, Tallini LR, Bastida J Plants (Basel) 10-Jan-2023
PMCID:PMC9866881
doi:10.3390/plants12020322
PMID:36679035
Endophytic bacteria from in vitro culture of Leucojum aestivum L. a new source of galanthamine and elicitor of alkaloid biosynthesis Ptak A, Morańska E, Warchoł M, Gurgul A, Skrzypek E, Dziurka M, Laurain-Mattar D, Spina R, Jaglarz A, Simlat M Sci Rep 11-Aug-2022
PMCID:PMC9371375
doi:10.1038/s41598-022-17992-5
PMID:35953692
A Review of African Medicinal Plants and Functional Foods for the Management of Alzheimer's Disease-related Phenotypes, Treatment of HSV-1 Infection and/or Improvement of Gut Microbiota Tettevi EJ, Maina M, Simpong DL, Osei-Atweneboana MY, Ocloo A J Evid Based Integr Med 21-Jul-2022
PMCID:PMC9310297
doi:10.1177/2515690X221114657
PMID:35866220
The Antibacterial, Antitumor Activities, and Bioactive Constituents’ Identification of Alectra sessiliflora Bacterial Endophytes Maela MP, van der Walt H, Serepa-Dlamini MH Front Microbiol 05-Jul-2022
PMCID:PMC9294510
doi:10.3389/fmicb.2022.870821
PMID:35865925
Ethnopharmacological Study of Medicinal Plants Used for the Treatment of Cardiovascular Diseases and Their Associated Risk Factors in sub-Saharan Africa Odukoya JO, Odukoya JO, Mmutlane EM, Ndinteh DT Plants (Basel) 23-May-2022
PMCID:PMC9143319
doi:10.3390/plants11101387
PMID:35631812
Lycorine Alkaloid and Crinum americanum L. (Amaryllidaceae) Extracts Display Antifungal Activity on Clinically Relevant Candida Species Silva LC, Correia AF, Gomes JV, Romão W, Motta LC, Fagg CW, Magalhães PO, Silveira D, Fonseca-Bazzo YM Molecules 06-May-2022
PMCID:PMC9100883
doi:10.3390/molecules27092976
PMID:35566325
Metabolomic Insights Into Endophyte-Derived Bioactive Compounds Mishra S, Priyanka, Sharma S Front Microbiol 02-Mar-2022
PMCID:PMC8926391
doi:10.3389/fmicb.2022.835931
PMID:35308367
Metabolomic profile of medicinal plants with anti-RVFV activity More GK, Vervoort J, Steenkamp PA, Prinsloo G Heliyon 12-Feb-2022
PMCID:PMC8857432
doi:10.1016/j.heliyon.2022.e08936
PMID:35243061
Medicinal Plants for Mitigating Pain and Inflammatory-Related Conditions: An Appraisal of Ethnobotanical Uses and Patterns in South Africa Aremu AO, Pendota SC Front Pharmacol 22-Oct-2021
PMCID:PMC8569556
doi:10.3389/fphar.2021.758583
PMID:34744737
Therapeutic applications and biological activities of bacterial bioactive extracts Abdelghani Z, Hourani N, Zaidan Z, Dbaibo G, Mrad M, Hage-Sleiman R Arch Microbiol 09-Aug-2021
PMCID:PMC8349711
doi:10.1007/s00203-021-02505-1
PMID:34370077
A Review of Plant-Based Therapies for the Treatment of Urinary Tract Infections in Traditional Southern African Medicine Cock I, Mavuso N, Van Vuuren S Evid Based Complement Alternat Med 29-Jul-2021
PMCID:PMC8346297
doi:10.1155/2021/7341124
PMID:34367307

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Amaryllidaceae alkaloids / Crinine- and Haemanthamine-type amaryllidaceae alkaloids
(+)-Crinamine 118701061 Click to see COC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O 301.34 unknown https://doi.org/10.1016/S0305-1978(02)00222-3
(11S,13beta,19S)-1,2-Didehydrocrinan-3alpha,11-diol 5282088 Click to see C1C(C=CC23C1N(CC2O)CC4=CC5=C(C=C34)OCO5)O 287.31 unknown https://doi.org/10.1016/S0305-1978(00)00096-X
(18-Hydroxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-15-yl) acetate 73657405 Click to see CC(=O)OC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O 329.30 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
(3R)-7-Methoxy-1,2-didehydrocrinan-3-ol 627287 Click to see COC1=C2CN3CCC4(C3CC(C=C4)O)C2=CC5=C1OCO5 301.34 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
https://doi.org/10.1016/S0031-9422(00)00128-X
https://doi.org/10.1021/NP100819N
[(1S,13R,15R)-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-15-yl] acetate 101935954 Click to see CC(=O)OC1CC2C3(CCN2CC4=CC5=C(C=C43)OCO5)C=C1 313.30 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
[(1S,13S,15S,18S)-18-hydroxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-15-yl] acetate 162963527 Click to see CC(=O)OC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O 329.30 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
1,2-Didehydrocrinan-3-ol 101727 Click to see C1CN2CC3=CC4=C(C=C3C15C2CC(C=C5)O)OCO4 271.31 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
11-Epicrinamine 5281172 Click to see COC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O 301.34 unknown https://doi.org/10.1016/S0305-1978(02)00222-3
https://doi.org/10.1016/S0367-326X(02)00164-8
3-O-Acetylhamayne 443671 Click to see CC(=O)OC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O 329.30 unknown https://doi.org/10.1016/S0305-1978(02)00222-3
https://doi.org/10.1016/S0367-326X(02)00164-8
9-Methoxy-5,7,17-trioxa-12-azahexacyclo[10.6.2.01,13.02,10.04,8.016,18]icosa-2,4(8),9-trien-15-ol 625708 Click to see COC1=C2CN3CCC4(C3CC(C5C4O5)O)C2=CC6=C1OCO6 317.34 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
https://doi.org/10.1016/S0031-9422(00)00128-X
9,15-Dimethoxy-5,7,17-trioxa-12-azahexacyclo[10.6.2.01,13.02,10.04,8.016,18]icosa-2,4(8),9-triene 271606 Click to see COC1CC2C3(CCN2CC4=C(C5=C(C=C43)OCO5)OC)C6C1O6 331.40 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Bulphanidine 407581 Click to see COC1CC2C3(CCN2CC4=C(C5=C(C=C43)OCO5)OC)C=C1 315.40 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Buphanidrine 338023 Click to see COC1CC2C3(CCN2CC4=C(C5=C(C=C43)OCO5)OC)C=C1 315.40 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Crinamidine 399204 Click to see COC1=C2CN3CCC4(C3CC(C5C4O5)O)C2=CC6=C1OCO6 317.34 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
https://doi.org/10.1016/S0031-9422(00)00128-X
Crinamin 73620 Click to see COC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O 301.34 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
Crinamine 500027 Click to see COC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O 301.34 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
Crinine 398937 Click to see C1CN2CC3=CC4=C(C=C3C15C2CC(C=C5)O)OCO4 271.31 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Hamayne 443670 Click to see C1C(C=CC23C1N(CC2O)CC4=CC5=C(C=C34)OCO5)O 287.31 unknown https://doi.org/10.1055/S-2004-818919
https://doi.org/10.1016/S0031-9422(00)00128-X
https://doi.org/10.1016/S0305-1978(00)00096-X
Powellin 443669 Click to see COC1=C2CN3CCC4(C3CC(C=C4)O)C2=CC5=C1OCO5 301.34 unknown https://doi.org/10.1016/S0305-1978(02)00222-3
https://doi.org/10.1016/S0031-9422(00)00128-X
https://doi.org/10.1016/S0367-326X(02)00164-8
Undulatine 3083985 Click to see COC1CC2C3(CCN2CC4=C(C5=C(C=C43)OCO5)OC)C6C1O6 331.40 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Vittatine acetate 541087 Click to see CC(=O)OC1CC2C3(CCN2CC4=CC5=C(C=C43)OCO5)C=C1 313.30 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Vittatine, 11-hydroxy- 602595 Click to see C1C(C=CC23C1N(CC2O)CC4=CC5=C(C=C34)OCO5)O 287.31 unknown https://doi.org/10.1021/NP100819N
> Alkaloids and derivatives / Amaryllidaceae alkaloids / Lycorine-type amaryllidaceae alkaloids
1-O-Acetyllycorine 443672 Click to see CC(=O)OC1C(C=C2CCN3C2C1C4=CC5=C(C=C4C3)OCO5)O 329.30 unknown https://doi.org/10.1016/S0305-1978(02)00222-3
https://doi.org/10.1016/S0367-326X(02)00164-8
Lycorine 72378 Click to see C1CN2CC3=CC4=C(C=C3C5C2C1=CC(C5O)O)OCO4 287.31 unknown https://doi.org/10.1016/S0305-1978(00)00096-X
https://doi.org/10.1016/S0031-9422(00)00128-X
https://doi.org/10.1016/S0305-1978(02)00222-3
https://doi.org/10.1055/S-2004-818919
> Benzenoids / Benzene and substituted derivatives / Phenethylamines
Tyramine 5610 Click to see C1=CC(=CC=C1CCN)O 137.18 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
https://doi.org/10.1016/S0305-1978(00)00096-X
> Organoheterocyclic compounds / Quinolines and derivatives / Benzoquinolines / Phenanthridines and derivatives
(17-Hydroxy-9-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9-trien-16-yl) acetate 75966350 Click to see CC(=O)OC1CCC2C3(C1O)CCN2CC4=C(C5=C(C=C34)OCO5)OC 361.40 unknown https://doi.org/10.1021/NP100819N
[(1S,13R,16S,17S)-17-acetyloxy-9-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9-trien-16-yl] acetate 132573533 Click to see CC(=O)OC1CCC2C3(C1OC(=O)C)CCN2CC4=C(C5=C(C=C34)OCO5)OC 403.40 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
1-Epideacetylbowdensine 443673 Click to see COC1=C2CN3CCC4(C3CCC(C4O)O)C2=CC5=C1OCO5 319.40 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
https://doi.org/10.1016/S0031-9422(00)00128-X
1H,6H-5,11b-Ethano[1,3]dioxolo[4,5-j]phenanthridine-1,2-diol, 2,3,4,4a-tetrahydro-7-methoxy- 629204 Click to see COC1=C2CN3CCC4(C3CCC(C4O)O)C2=CC5=C1OCO5 319.40 unknown https://doi.org/10.1016/S0367-326X(02)00164-8
https://doi.org/10.1016/S0031-9422(00)00128-X
2-O-Acetylbulbisine 56928078 Click to see CC(=O)OC1CCC2C3(C1O)CCN2CC4=C(C5=C(C=C34)OCO5)OC 361.40 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
4-Methoxy-9-azatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6,13-tetraene-5,12-diol 494912 Click to see COC1=C(C=C2CN3CCC4(C3CC(C=C4)O)C2=C1)O 273.33 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
4a-Dehydroxycrinamabine 398935 Click to see C1CC2C3(CCN2CC4=CC5=C(C=C43)OCO5)C(C1O)O 289.33 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
5,7-Dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9-triene-16,17-diol 74952092 Click to see C1CC2C3(CCN2CC4=CC5=C(C=C43)OCO5)C(C1O)O 289.33 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Bowdensine 541341 Click to see CC(=O)OC1CCC2C3(C1OC(=O)C)CCN2CC4=C(C5=C(C=C34)OCO5)OC 403.40 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Macowine 637191 Click to see COC1=C(C=C2CN3CCC4(C3CC(C=C4)O)C2=C1)O 273.33 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
> Organoheterocyclic compounds / Tetrahydroisoquinolines / 4-phenyltetrahydroisoquinolines
2-Methyl-4-(4-hydroxyphenyl)-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline 618047 Click to see CN1CC(C2=CC(=C(C=C2C1)O)OC)C3=CC=C(C=C3)O 285.34 unknown https://doi.org/10.1016/S0031-9422(00)00128-X
Cherylline 90075 Click to see CN1CC(C2=CC(=C(C=C2C1)O)OC)C3=CC=C(C=C3)O 285.34 unknown https://doi.org/10.1016/S0305-1978(02)00222-3
https://doi.org/10.1016/S0305-1978(00)00096-X
https://doi.org/10.1016/S0031-9422(00)00128-X

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