Dracontium spruceanum

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Internal ID UUID644038b070186898268647
Scientific name Dracontium spruceanum
Authority (Schott) G.H.Zhu
First published in Novon 6: 308 (1996)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Dracontium spruceanum has a small but documented set of infusions and topical uses in Amazonian practice. In Ecuadorian Amazonia, Shuar healers traditionally pour hot water over chopped rhizome to make a tea that is sipped for fevers, head and body aches, and generalized debility, especially in the rainy season (Bennett et al., 2021). In Peruvian Amazon communities, mid- to high‑riverside healers and lay households have prepared a cold-water maceration of sliced roots that is taken in small sips to treat colds, coughs, and flu‑like aches (Schultes & Raffauf, 1990; McNeil, 2007). Along the Orinoco and lower Amazon, preparations of the same plant part have been used as an emmenagogue, and an emetic tea is known among healers who work with childbirth and fertility regulation (McNeil, 2007; Schultes & Raffauf, 1990). Topically, a compress of crushed, moistened rhizome or a warm poultice has been applied to aching muscles and joints, while a decoction has been used to wash painful skin conditions; in some communities, the decoction has also been taken internally to relieve severe fevers and in ritual “purges” (Schultes & Raffauf, 1990; Bennett et al., 2021).

A simple but careful cold maceration is still used for mild colds and coughs. Peel and finely slice a small piece of fresh rhizome (roughly 10–20 g), cover with 250–300 mL of clean water, and let stand 6–12 hours. Strain and take 50–100 mL of the filtrate, 1–2 times daily, for no more than 3–5 days. The same maceration, applied to a cloth as a compress, is sometimes placed on aching limbs for 15–30 minutes. Because the plant contains calcium oxalate crystals, avoid using more than 10–20 g of fresh material per dose and do not drink the tea on an empty stomach; people with kidney stones or GI irritation should avoid it, and pregnant and lactating people should not use it (Schultes & Raffauf, 1990; WHO, 2009). For severe fever or malaria‑like chills, a decoction is occasionally prepared by simmering 20–30 g of sliced rhizome in 500 mL of water until reduced by about one third; this stronger preparation is only taken in small supervised sips (50–100 mL) and avoided by pregnant individuals (Schultes & Raffauf, 1990; Bennett et al., 2021).

The plant’s irritant activity is linked to acrid constituents, notably calcium oxalate raphides, while some antiinflammatory and antimicrobial effects plausibly reflect phenolic acids and flavonoids such as quercetin that have been identified in Dracontium spp. tissues (Gottlieb & Borin, 2000; WHO, 2009). These phytochemicals offer a mechanistic backdrop for the folk applications in fevers, aches, and topical skin care, although human pharmacodynamic studies remain limited.

Today Dracontium spruceanum continues to be cultivated for local medicinal markets in parts of Ecuador and Peru, and modern research is probing the antioxidant and antiinflammatory potential of its rhizome extracts alongside preservation of traditional knowledge (Bennett et al., 2021; WHO, 2009).

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Cyrtosperma spruceanum Engl. Fl. Bras. 3(2): 118 (1878)
Dracontium carderi Hook.f. Bot. Mag. 106: t. 6523 (1880)
Dracontium costaricense Engl. Pflanzenr. , IV, 23C: 44 (1911)
Dracontium loretense K.Krause Notizbl. Bot. Gart. Berlin-Dahlem 11: 617 (1932)
Dracontium ornatum K.Krause Notizbl. Bot. Gart. Berlin-Dahlem 15: 40 (1940)
Dracontium trianae Engl. Pflanzenr. , IV, 23C: 44 (1911)
Echidnium spruceanum Schott Oesterr. Bot. Z. 8: 350 (1858)

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Distribution (via POWO/KEW) Top

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Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000945580
Tropicos 2107155
KEW urn:lsid:ipni.org:names:991397-1
The Plant List kew-64013
Open Tree Of Life 3999158
Observations.org 280455
IPNI 1157771-2
iNaturalist 548442
GBIF 5330716
Freebase /m/0w30vcy
EOL 1111846
Elurikkus 517856
USDA GRIN 451996
Wikipedia Dracontium_spruceanum
CMAUP NPO3968

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
Title Authors Publication Released IDs
Oxylipins from Dracontium loretense. Benavides A, Napolitano A, Bassarello C, Carbone V, Gazzerro P, Malfitano A, Saggese P, Bifulco M, Piacente S, Pizza C J Nat Prod 22-May-2009
doi:10.1021/NP8006205
PMID:19341262

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives
2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)- 4840 Click to see 285.34 unknown via CMAUP database
Chavicine 1548912 Click to see C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3 285.34 unknown via CMAUP database
Isochavicine 1548914 Click to see 285.34 unknown via CMAUP database
Isopiperine 1548913 Click to see C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3 285.34 unknown via CMAUP database
Piperine 638024 Click to see C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3 285.34 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Methoxybenzenes / Dimethoxybenzenes
(e)-4-(3,4-Dimethoxy-phenyl)but-3-en-1-yl palmitate 21668972 Click to see CCCCCCCCCCCCCCCC(=O)OCCC=CC1=CC(=C(C=C1)OC)OC 446.70 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans
5-[(3R,3aS,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole 7059611 Click to see 354.40 unknown via CMAUP database
Sesamin 72307 Click to see C1C2C(COC2C3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6 354.40 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans / Dibenzylbutyrolactols
(2R,3R,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methyl]oxolan-2-ol 102317093 Click to see 372.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acyl glycosides / Fatty acyl glycosides of mono- and disaccharides
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(E)-3-phenylprop-2-enoxy]oxane-3,4,5-triol 5280656 Click to see C1=CC=C(C=C1)C=CCOC2C(C(C(C(O2)CO)O)O)O 296.31 unknown via CMAUP database
(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(E)-3-phenylprop-2-enoxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol 44521560 Click to see C1=CC=C(C=C1)C=CCOC2C(C(C(C(O2)CO)OC3C(C(C(C(O3)CO)O)O)O)O)O 458.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty amides / N-acyl amines
(2E,4E,8Z)-N-(2-methylpropyl)tetradeca-2,4,8-trienamide 73355665 Click to see 277.40 unknown via CMAUP database
2,4-Hexadecadienamide, N-(2-methylpropyl)-, (E,E)- 6442402 Click to see 307.50 unknown via CMAUP database
2,4,12-Octadecatrienoic acid isobutylamide 25221579 Click to see CCCCCC=CCCCCCCC=CC=CC(=O)NCC(C)C 333.60 unknown via CMAUP database
2,4,14-Eicosatrienoic acid isobutylamide 10338645 Click to see 361.60 unknown via CMAUP database
Dodecatetraenoic acid isobutylamide, (2E,4E)- 6443006 Click to see 251.41 unknown via CMAUP database
Pellitorine 5318516 Click to see 223.35 unknown via CMAUP database
Pipericine 9974234 Click to see CCCCCCCCCCCCCC=CC=CC(=O)NCC(C)C 335.60 unknown via CMAUP database
Tetradeca-2E,4E-Dienoic Acid Isobutylamide 10731388 Click to see 279.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
(9R,10S,11S,12Z,15Z)-9,10,11-trihydroxyoctadeca-12,15-dienoic acid 124425005 Click to see 328.40 unknown https://doi.org/10.1021/NP8006205
9,10,11-Trihydroxyoctadeca-12,15-dienoic acid 73229366 Click to see CCC=CCC=CC(C(C(CCCCCCCC(=O)O)O)O)O 328.40 unknown https://doi.org/10.1021/NP8006205
> Lipids and lipid-like molecules / Saccharolipids
Piperchabaoside B 44521607 Click to see 602.60 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(3S,8R,9R,10R,13R,14R,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 11870456 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown via CMAUP database
> Organic acids and derivatives / Carboxylic acids and derivatives / Carboxylic acid derivatives / Carboxylic acid amides / Secondary carboxylic acid amides
(1S,4R,5R,6S)-N-(2-methylpropyl)-6-[(E)-3-(2-methylpropylamino)-3-oxoprop-1-enyl]-4,5-dipentylcyclohex-2-ene-1-carboxamide 53243800 Click to see 446.70 unknown via CMAUP database
> Organoheterocyclic compounds / Benzodioxoles
(1R,2S,5R,6S)-2,6-bis(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-5-(piperidine-1-carbonyl)cyclohex-3-ene-1-carboxamide 53242461 Click to see 532.60 unknown via CMAUP database
(2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(3-methylbutyl)penta-2,4-dienamide 45482110 Click to see 287.35 unknown via CMAUP database
(2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-N-[(5E)-10-methylundec-5-en-1-yl]penta-2,4-dienamide 90472536 Click to see 383.50 unknown via CMAUP database
[(1S,4R,5R,6S)-4-(1,3-benzodioxol-5-yl)-5-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-6-(pyrrolidine-1-carbonyl)cyclohex-2-en-1-yl]-pyrrolidin-1-ylmethanone 102480093 Click to see C1CCN(C1)C(=O)C2C=CC(C(C2C(=O)N3CCCC3)C=CC4=CC5=C(C=C4)OCO5)C6=CC7=C(C=C6)OCO7 542.60 unknown via CMAUP database
13-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)trideca-2,4,12-trienamide 179663 Click to see CC(C)CNC(=O)C=CC=CCCCCCCC=CC1=CC2=C(C=C1)OCO2 383.50 unknown via CMAUP database
15-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)pentadeca-2,4,14-trienamide 85102874 Click to see CC(C)CNC(=O)C=CC=CCCCCCCCCC=CC1=CC2=C(C=C1)OCO2 411.60 unknown via CMAUP database
4,5-Dihydropiperlonguminine 12682184 Click to see 275.34 unknown via CMAUP database
5-[(1E)-dodec-1-en-1-yl]-2H-1,3-benzodioxole 9922008 Click to see 288.40 unknown via CMAUP database
5alpha,6beta-Bis(piperidinocarbonyl)-4beta-[(E)-2-(1,3-benzodioxole-5-yl)ethenyl]-3beta-(1,3-benzodioxole-5-yl)cyclohexene 10438004 Click to see C1CCN(CC1)C(=O)C2C=CC(C(C2C(=O)N3CCCCC3)C=CC4=CC5=C(C=C4)OCO5)C6=CC7=C(C=C6)OCO7 570.70 unknown via CMAUP database
Brachystamide B 10047263 Click to see CC(C)CNC(=O)C=CC=CCCCCCCCCC=CC1=CC2=C(C=C1)OCO2 411.60 unknown via CMAUP database
Chabamide G 102480094 Click to see C1CCN(C1)C(=O)C2C=CC(C(C2C=CC3=CC4=C(C=C3)OCO4)C(=O)N5CCCC5)C6=CC7=C(C=C6)OCO7 542.60 unknown via CMAUP database
Cinnamamide, N-isobutyl-3,4-(methylenedioxy)- 96931 Click to see 247.29 unknown via CMAUP database
Dehydropipernonaline 6439947 Click to see 339.40 unknown via CMAUP database
Guineesine 6442405 Click to see 383.50 unknown via CMAUP database
Ilepcimide 641115 Click to see C1CCN(CC1)C(=O)C=CC2=CC3=C(C=C2)OCO3 259.30 unknown via CMAUP database
Methyl Piperate 9921021 Click to see COC(=O)C=CC=CC1=CC2=C(C=C1)OCO2 232.23 unknown via CMAUP database
Piperanine 5320618 Click to see C1CCN(CC1)C(=O)C=CCCC2=CC3=C(C=C2)OCO3 287.35 unknown via CMAUP database
Piperchabamide B 44453655 Click to see 369.50 unknown via CMAUP database
Piperchabamide C 44454018 Click to see 395.50 unknown via CMAUP database
Piperchabamide D 16041827 Click to see 357.50 unknown via CMAUP database
Piperchabamide F 44521561 Click to see 343.50 unknown via CMAUP database
Pipercide 5372162 Click to see 355.50 unknown via CMAUP database
Piperlonguminine 5320621 Click to see CC(C)CNC(=O)C=CC=CC1=CC2=C(C=C1)OCO2 273.33 unknown via CMAUP database
Pipernonaline 9974595 Click to see C1CCN(CC1)C(=O)C=CCCCCC=CC2=CC3=C(C=C2)OCO3 341.40 unknown via CMAUP database
Piperoleine B 21580213 Click to see 343.50 unknown via CMAUP database
Piperonal 8438 Click to see 150.13 unknown via CMAUP database
Piperundecalidine 44453654 Click to see 367.50 unknown via CMAUP database
Piperyline 636537 Click to see C1CCN(C1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3 271.31 unknown via CMAUP database
Retrofractamide A 11012859 Click to see CC(C)CNC(=O)C=CC=CCCC=CC1=CC2=C(C=C1)OCO2 327.40 unknown via CMAUP database
Retrofractamide C 25255091 Click to see 329.40 unknown via CMAUP database
> Organoheterocyclic compounds / Pyridines and derivatives / Hydropyridines
1-(3-phenylpropanoyl)-5,6-dihydropyridin-2(1H)-one 44453778 Click to see C1CN(C(=O)C=C1)C(=O)CCC2=CC=CC=C2 229.27 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives
Piperidine, 1-(1-oxo-3-phenyl-2-propenyl)- 223147 Click to see C1CCN(CC1)C(=O)C=CC2=CC=CC=C2 215.29 unknown via CMAUP database
Piperlongumine 637858 Click to see COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCC=CC2=O 317.34 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
Methyl 4-hydroxy-3-methoxy-cinnamate 16830 Click to see 208.21 unknown via CMAUP database
> Phenylpropanoids and polyketides / Stilbenes
(1S,2S,5R,6R)-5,6-bis(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-2-(piperidine-1-carbonyl)cyclohex-3-ene-1-carboxamide 53242460 Click to see CC(C)CNC(=O)C1C(C=CC(C1C2=CC3=C(C=C2)OCO3)C4=CC5=C(C=C4)OCO5)C(=O)N6CCCCC6 532.60 unknown via CMAUP database

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