Tyledoside G

Details

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Internal ID bc6081ad-79d2-404e-8f4f-3d8f06639b6d
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Steroid lactones > Bufanolides and derivatives
IUPAC Name 5-(8,13,26-trihydroxy-1-methoxy-5,9,24-trimethyl-2,15,21,23-tetraoxaheptacyclo[20.3.1.03,20.05,18.06,14.09,13.014,16]hexacosan-10-yl)pyran-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H42O10/c1-15-12-29(36-4)25(34)26(38-15)39-19-9-17-10-23-31(41-23)21(27(17,2)13-20(19)40-29)11-22(32)28(3)18(7-8-30(28,31)35)16-5-6-24(33)37-14-16/h5-6,14-15,17-23,25-26,32,34-35H,7-13H2,1-4H3
InChI Key HYFHVAKYSKJTGB-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C31H42O10
Molecular Weight 574.70 g/mol
Exact Mass 574.27779753 g/mol
Topological Polar Surface Area (TPSA) 136.00 Ų
XlogP 1.00

Synonyms

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Tyledoside G
DTXSID50907999
5-(3a,16,17-Trihydroxy-12-methoxy-10,14a,16a-trimethyloctadecahydro-8H,10H-8,12-methanocyclopenta[7,8]oxireno[8a,9]phenanthro[2,3-d][1,3,6]trioxonin-1-yl)-2H-pyran-2-one

2D Structure

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2D Structure of Tyledoside G

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.87% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.92% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.87% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.69% 97.25%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.20% 86.33%
CHEMBL1951 P21397 Monoamine oxidase A 91.08% 91.49%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.08% 95.56%
CHEMBL2581 P07339 Cathepsin D 89.02% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.88% 91.11%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.38% 89.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.89% 95.89%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 86.78% 94.00%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 85.88% 100.00%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 85.53% 93.04%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.21% 99.23%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 84.00% 82.69%
CHEMBL4208 P20618 Proteasome component C5 83.65% 90.00%
CHEMBL3922 P50579 Methionine aminopeptidase 2 83.12% 97.28%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 82.03% 94.45%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.45% 100.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 81.13% 100.00%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 80.15% 96.77%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Tylecodon grandiflorus

Cross-Links

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PubChem 190431
LOTUS LTS0123481
wikiData Q82877346