Phosphoserine

Details

• Internal ID: 6271cd68-5bf4-4926-bc95-9b5359e26af1
• Taxonomy: Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > Alpha amino acids > L-alpha-amino acids
• IUPAC Name: (2S)-2-amino-3-phosphonooxypropanoic acid
• SMILES (Canonical): C(C(C(=O)O)N)OP(=O)(O)O
• SMILES (Isomeric): C([C@@H](C(=O)O)N)OP(=O)(O)O
• InChI: InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
• InChI Key: BZQFBWGGLXLEPQ-REOHCLBHSA-N
• Popularity: 20,057 references in papers

Physical and Chemical Properties

• Molecular Formula: C₃H₈NO₆P
• Molecular Weight: 185.07 g/mol
• Exact Mass: 185.00892397 g/mol
• Topological Polar Surface Area (TPSA): 130.00 Ų
• XlogP: -5.10

Synonyms

• Dexfosfoserine
• phosphoserine
• 407-41-0
• L-O-Phosphoserine
• Fosforina
• L-SOP
• O-Phosphoserine
• L-Phosphoserine
• L-Serine O-phosphate
• PHOSPHONOSERINE
• 3-phosphoserine
• H-Ser(PO3H2)-OH
• Dexfosfoserine [INN]
• seriphos
• L-serine-O-phosphate
• O-phosphono-L-serine
• L-O-Serine phosphate
• Phosphatidalserine
• 3-O-Phosphoserine
• (+)-L-Serine dihydrogen phosphate (ester)
• O-Phosphoryl-L-serine
• L-2-amino-3-hydroxypropanoic acid 3-phosphate
• (2S)-2-amino-3-phosphonooxypropanoic acid
• L-Seryl phosphate
• L-3-Phosphoserine
• Serine O-phosphate
• GNF-Pf-1028
• serine phosphate
• O-phosphoserine, l-
• L-Serinephosphoric acid
• L-serine, O-phosphono-
• NSC-760136
• CHEMBL284377
• VI4F0K069V
• DTXSID1046348
• (2S)-2-amino-3-(phosphonooxy)propanoic acid
• CHEBI:15811
• L-Serine, dihydrogen phosphate (ester)
• L-Serine phosphate
• 3-phospho-L-serine
• (S)-2-amino-3-hydroxypropanoic acid 3-phosphate
• SEP
• C3H8NO6P
• DTXCID9026348
• CAS-407-41-0
• LSOP
• PHOSPHOSERINE, DL-
• EINECS 206-986-0
• UNII-VI4F0K069V
• Plasmenylserine
• O3-phosphoserine
• Phospho-L-serine
• O-Phosphorylserine
• L-Serinephosphorate
• NCGC00163344-01
• Serine dihydrogen phosphate (ester)
• MFCD00065935
• Serine, O-phospho-
• serine phosphate ester
• Tocris-0238
• H-Ser(PO)-OH
• PHOSPHOSERINE [MI]
• bmse000399
• SCHEMBL6846
• Lopac0_000886
• SERINE PHOSPHATE, L-
• L-Serine, dihydrogen phosphate
• Serine phosphate, L- (6CI)
• GTPL1411
• DEXFOSFOSERINE [WHO-DD]
• BDBM17664
• HMS3262B14
• HMS3264A13
• Pharmakon1600-01506151
• Tox21_112050
• Tox21_500886
• HB0475
• NSC760136
• s5137
• O-Phospho-L-serine, ~95% (TLC)
• AKOS006239311
• L-Serine dihydrogen phosphate (ester)
• Tox21_112050_1
• CCG-204968
• CS-7902
• DB04522
• LP00886
• NSC 760136
• SDCCGSBI-0050861.P002
• NCGC00024512-01
• NCGC00024512-02
• NCGC00024512-03
• NCGC00024512-04
• NCGC00024512-05
• NCGC00024512-06
• NCGC00024512-07
• NCGC00024512-11
• NCGC00261571-01
• HY-15129
• (S)-2-Amino-3-(phosphonooxy)propanoic acid
• EU-0100886
• P0773
• <span class='DL'>L</span>-Serine-O-phosphate
• C01005
• F10885
• L-Serine, dihydrogen phosphate (ester) (9CI)
• P 0878
• AB01563211_01
• A873241
• SERINE, DIHYDROGEN PHOSPHATE (ESTER), L-
• Serine, dihydrogen phosphate (ester), L- (8CI)
• SR-01000597714
• Q2701649
• SR-01000597714-1
• F1EE42DE-E913-4F09-A97B-F539EE869AB7
• O-Phospho-L-serine, certified reference material, TraceCERT(R)

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

CHEMBL ID	UniProt ID	Name	Min activity	Assay type	Source
CHEMBL1293237	P54132	Bloom syndrome protein	2.8 nM	Potency	via Super-PRED

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL4040	P28482	MAP kinase ERK2	97.89%	83.82%
CHEMBL3230	O95977	Sphingosine 1-phosphate receptor Edg-6	96.01%	94.01%
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	95.98%	96.09%
CHEMBL3892	Q99500	Sphingosine 1-phosphate receptor Edg-3	95.87%	97.29%
CHEMBL2288	Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	88.15%	91.71%
CHEMBL3060	Q9Y345	Glycine transporter 2	85.92%	99.17%
CHEMBL335	P18031	Protein-tyrosine phosphatase 1B	83.91%	95.17%
CHEMBL3976	Q9UHL4	Dipeptidyl peptidase II	82.83%	92.29%

Plants that contains it

• Prunus domestica

Cross-Links

• PubChem: 68841
• LOTUS: LTS0108147
• wikiData: Q2701649