Orizabin VIII

Details

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Internal ID dfd717bc-1c2d-4d13-b9cb-7faf37f7c32a
Taxonomy Lipids and lipid-like molecules > Saccharolipids
IUPAC Name [(1S,3R,4S,5S,6R,8R,10S,22S,23R,24R,26R)-4,5,23-trihydroxy-26-[(2S,3R,4R,5R,6S)-4-hydroxy-6-methyl-3-[(2S)-2-methylbutanoyl]oxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-6-methyl-20-oxo-10-pentyl-2,7,9,21,25-pentaoxatricyclo[20.3.1.03,8]hexacosan-24-yl]methyl (2R,3R)-3-hydroxy-2-methylbutanoate
SMILES (Canonical) CCCCCC1CCCCCCCCCC(=O)OC2C(C(OC(C2OC3C(C(C(C(O3)C)OC4C(C(C(C(O4)C)O)O)O)O)OC(=O)C(C)CC)OC5C(C(C(OC5O1)C)O)O)COC(=O)C(C)C(C)O)O
SMILES (Isomeric) CCCCC[C@H]1CCCCCCCCCC(=O)O[C@H]2[C@@H]([C@H](O[C@H]([C@@H]2O[C@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C)O)O)O)O)OC(=O)[C@@H](C)CC)O[C@@H]5[C@H]([C@@H]([C@H](O[C@H]5O1)C)O)O)COC(=O)[C@H](C)[C@@H](C)O)O
InChI InChI=1S/C50H86O22/c1-9-11-17-20-30-21-18-15-13-12-14-16-19-22-32(52)68-41-35(55)31(23-62-46(61)25(4)26(5)51)67-50(71-42-37(57)34(54)28(7)64-48(42)66-30)44(41)72-49-43(69-45(60)24(3)10-2)39(59)40(29(8)65-49)70-47-38(58)36(56)33(53)27(6)63-47/h24-31,33-44,47-51,53-59H,9-23H2,1-8H3/t24-,25+,26+,27+,28+,29-,30-,31+,33+,34+,35+,36-,37-,38+,39+,40-,41-,42+,43+,44+,47-,48-,49-,50-/m0/s1
InChI Key MTNNYMSRZLOLMA-SUEAJDNPSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C50H86O22
Molecular Weight 1039.20 g/mol
Exact Mass 1038.56107437 g/mol
Topological Polar Surface Area (TPSA) 315.00 Ų
XlogP 3.40

Synonyms

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CHEMBL500529

2D Structure

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2D Structure of Orizabin VIII

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.15% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.94% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.87% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.71% 91.11%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 94.98% 96.38%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 94.23% 96.47%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 93.43% 100.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 93.11% 92.62%
CHEMBL3359 P21462 Formyl peptide receptor 1 91.72% 93.56%
CHEMBL218 P21554 Cannabinoid CB1 receptor 90.69% 96.61%
CHEMBL5255 O00206 Toll-like receptor 4 90.01% 92.50%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.84% 89.00%
CHEMBL4072 P07858 Cathepsin B 89.26% 93.67%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 88.74% 83.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 88.45% 99.17%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 88.42% 94.33%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 88.18% 96.77%
CHEMBL340 P08684 Cytochrome P450 3A4 88.17% 91.19%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.00% 97.09%
CHEMBL5957 P21589 5'-nucleotidase 87.81% 97.78%
CHEMBL1968 P07099 Epoxide hydrolase 1 87.43% 98.57%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.33% 90.71%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 87.05% 90.24%
CHEMBL2345 P51812 Ribosomal protein S6 kinase alpha 3 86.36% 95.64%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 84.65% 95.50%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 84.15% 98.75%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 83.99% 95.71%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.33% 95.89%
CHEMBL3401 O75469 Pregnane X receptor 83.17% 94.73%
CHEMBL2996 Q05655 Protein kinase C delta 82.47% 97.79%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.35% 100.00%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 81.80% 96.25%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.66% 96.00%
CHEMBL221 P23219 Cyclooxygenase-1 81.30% 90.17%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 81.27% 96.90%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 81.08% 92.88%
CHEMBL2514 O95665 Neurotensin receptor 2 80.76% 100.00%
CHEMBL3714130 P46095 G-protein coupled receptor 6 80.32% 97.36%
CHEMBL3004 P33527 Multidrug resistance-associated protein 1 80.30% 96.37%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Ipomoea orizabensis

Cross-Links

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PubChem 21635820
LOTUS LTS0192377
wikiData Q105171785