Nuevamine

Details

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Internal ID a1982eb6-4e03-42d2-9157-ea32ebee0ba6
Taxonomy Organoheterocyclic compounds > Isoindoles and derivatives > Pyridoisoindoles
IUPAC Name 4,5-dimethoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,10.03,8.015,19]icosa-1(20),3(8),4,6,13,15(19)-hexaen-9-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C19H17NO5/c1-22-13-4-3-11-16(18(13)23-2)17-12-8-15-14(24-9-25-15)7-10(12)5-6-20(17)19(11)21/h3-4,7-8,17H,5-6,9H2,1-2H3
InChI Key FANIZYOYPJRPLY-UHFFFAOYSA-N
Popularity 7 references in papers

Physical and Chemical Properties

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Molecular Formula C19H17NO5
Molecular Weight 339.30 g/mol
Exact Mass 339.11067264 g/mol
Topological Polar Surface Area (TPSA) 57.20 Ų
XlogP 2.40

Synonyms

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4,5-dimethoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,10.03,8.015,19]icosa-1(20),3(8),4,6,13,15(19)-hexaen-9-one

2D Structure

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2D Structure of Nuevamine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.26% 98.95%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 97.04% 96.77%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.49% 96.09%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 93.99% 93.40%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.81% 86.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.57% 95.56%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 93.16% 82.67%
CHEMBL4247 Q9UM73 ALK tyrosine kinase receptor 91.56% 96.86%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.23% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.95% 89.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 87.87% 91.11%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 87.41% 89.62%
CHEMBL2056 P21728 Dopamine D1 receptor 87.39% 91.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.24% 97.25%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.06% 90.71%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.61% 94.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.59% 92.62%
CHEMBL4895 P30530 Tyrosine-protein kinase receptor UFO 85.23% 90.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.90% 94.45%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.93% 97.14%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 83.63% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 83.28% 85.14%
CHEMBL2535 P11166 Glucose transporter 83.16% 98.75%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.82% 100.00%
CHEMBL261 P00915 Carbonic anhydrase I 82.13% 96.76%
CHEMBL4940 P07195 L-lactate dehydrogenase B chain 81.66% 95.53%
CHEMBL4208 P20618 Proteasome component C5 81.64% 90.00%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 81.19% 94.78%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 80.59% 90.24%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.34% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Berberis darwinii

Cross-Links

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PubChem 11772134
LOTUS LTS0103660
wikiData Q104992362