Norglaucin

Details

• Internal ID: 1f7d9bbd-6aa8-48b5-8bbf-ea5671f87c74
• Taxonomy: Alkaloids and derivatives > Aporphines
• IUPAC Name: (6aS)-1,2,9,10-tetramethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
• SMILES (Canonical): COC1=C(C2=C3C(CC4=CC(=C(C=C42)OC)OC)NCCC3=C1)OC
• SMILES (Isomeric): COC1=C(C2=C3[C@H](CC4=CC(=C(C=C42)OC)OC)NCCC3=C1)OC
• InChI: InChI=1S/C20H23NO4/c1-22-15-9-12-7-14-18-11(5-6-21-14)8-17(24-3)20(25-4)19(18)13(12)10-16(15)23-2/h8-10,14,21H,5-7H2,1-4H3/t14-/m0/s1
• InChI Key: MZSUVQFIWWXTFR-AWEZNQCLSA-N
• Popularity: 0 references in papers

Physical and Chemical Properties

• Molecular Formula: C₂₀H₂₃NO₄
• Molecular Weight: 341.40 g/mol
• Exact Mass: 341.16270821 g/mol
• Topological Polar Surface Area (TPSA): 49.00 Ų
• XlogP: 2.90

Synonyms

• Norglaucine
• 21848-62-4
• (6aS)-1,2,9,10-tetramethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
• O,O-Dimethyllaurelliptine
• d-N-Norglaucine
• (+)-N-Norglaucine
• Laurelliptine, O,O'-dimethyl-
• 1,2,9,10-Tetramethoxy-6a-alpha-noraporphine
• 6a-alpha-NORAPORPHINE, 1,2,9,10-TETRAMETHOXY-
• DTXSID00176254
• CHEBI:181571
• MZSUVQFIWWXTFR-AWEZNQCLSA-N
• HY-N9339
• AKOS040763720
• Laurelliptine, O,O'-dimethyl- (7CI)
• 4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-, (S)-
• CS-0159482

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	95.43%	96.09%
CHEMBL3192	Q9BY41	Histone deacetylase 8	92.82%	93.99%
CHEMBL3137262	O60341	LSD1/CoREST complex	92.34%	97.09%
CHEMBL241	Q14432	Phosphodiesterase 3A	91.64%	92.94%
CHEMBL2535	P11166	Glucose transporter	88.90%	98.75%
CHEMBL1293249	Q13887	Kruppel-like factor 5	88.60%	86.33%
CHEMBL5747	Q92793	CREB-binding protein	88.47%	95.12%
CHEMBL3880	P07900	Heat shock protein HSP 90-alpha	88.03%	96.21%
CHEMBL5619	P27695	DNA-(apurinic or apyrimidinic site) lyase	87.65%	91.11%
CHEMBL3438	Q05513	Protein kinase C zeta	87.48%	88.48%
CHEMBL4208	P20618	Proteasome component C5	86.76%	90.00%
CHEMBL3060	Q9Y345	Glycine transporter 2	86.64%	99.17%
CHEMBL5608	Q16288	NT-3 growth factor receptor	86.41%	95.89%
CHEMBL213	P08588	Beta-1 adrenergic receptor	86.28%	95.56%
CHEMBL217	P14416	Dopamine D2 receptor	85.29%	95.62%
CHEMBL215	P09917	Arachidonate 5-lipoxygenase	84.99%	92.68%
CHEMBL5469	Q14289	Protein tyrosine kinase 2 beta	81.84%	91.03%
CHEMBL2056	P21728	Dopamine D1 receptor	81.43%	91.00%
CHEMBL2635	P51452	Dual specificity protein phosphatase 3	81.39%	94.00%
CHEMBL2581	P07339	Cathepsin D	80.88%	98.95%
CHEMBL4657	Q6V1X1	Dipeptidyl peptidase VIII	80.75%	97.21%
CHEMBL4306	P22460	Voltage-gated potassium channel subunit Kv1.5	80.46%	94.03%
CHEMBL5925	P22413	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	80.33%	92.38%

Plants that contains it

• Annona purpurea
• Chasmanthera dependens
• Corydalis turtschaninovii
• Corydalis yanhusuo
• Hortia oreadica
• Liriodendron tulipifera
• Xylopia parviflora

Cross-Links

• PubChem: 30835
• LOTUS: LTS0137986
• wikiData: Q104995936