Kanzonol J

Details

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Internal ID f47a0695-ca4b-4e20-ae60-a77ac6492019
Taxonomy Phenylpropanoids and polyketides > Isoflavonoids > Pyranoisoflavonoids
IUPAC Name 8-(5-methoxy-2,2-dimethyl-4,6,7,8-tetrahydro-3H-pyrano[3,2-g]chromen-7-yl)-2,2-dimethylchromen-5-ol
SMILES (Canonical) CC1(CCC2=C(C3=C(C=C2O1)OCC(C3)C4=C5C(=C(C=C4)O)C=CC(O5)(C)C)OC)C
SMILES (Isomeric) CC1(CCC2=C(C3=C(C=C2O1)OCC(C3)C4=C5C(=C(C=C4)O)C=CC(O5)(C)C)OC)C
InChI InChI=1S/C26H30O5/c1-25(2)11-9-18-22(30-25)13-21-19(23(18)28-5)12-15(14-29-21)16-6-7-20(27)17-8-10-26(3,4)31-24(16)17/h6-8,10,13,15,27H,9,11-12,14H2,1-5H3
InChI Key POHNDGZXXXCXFF-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C26H30O5
Molecular Weight 422.50 g/mol
Exact Mass 422.20932405 g/mol
Topological Polar Surface Area (TPSA) 57.20 Ų
XlogP 5.20

Synonyms

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CHEBI:171727
8-(5-methoxy-2,2-dimethyl-4,6,7,8-tetrahydro-3H-pyrano[3,2-g]chromen-7-yl)-2,2-dimethylchromen-5-ol

2D Structure

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2D Structure of Kanzonol J

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.73% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.81% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.50% 96.09%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 96.69% 93.40%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 90.97% 99.15%
CHEMBL2535 P11166 Glucose transporter 89.19% 98.75%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.13% 86.33%
CHEMBL3192 Q9BY41 Histone deacetylase 8 88.14% 93.99%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.09% 95.89%
CHEMBL2581 P07339 Cathepsin D 88.05% 98.95%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 88.05% 100.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.58% 97.09%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.18% 92.62%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.62% 89.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.18% 100.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 84.59% 93.56%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 83.36% 80.96%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 83.34% 92.88%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.04% 97.14%
CHEMBL340 P08684 Cytochrome P450 3A4 82.60% 91.19%
CHEMBL213 P08588 Beta-1 adrenergic receptor 81.82% 95.56%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 80.92% 95.56%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 80.87% 89.05%
CHEMBL3060 Q9Y345 Glycine transporter 2 80.85% 99.17%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 80.60% 82.67%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Glycyrrhiza uralensis

Cross-Links

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PubChem 131752862
LOTUS LTS0208294
wikiData Q104402847