Kadangustin B

Details

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Internal ID 2bb66695-b4e8-44f9-a037-7ba6c60437c0
Taxonomy Phenylpropanoids and polyketides > Tannins > Hydrolyzable tannins
IUPAC Name [(11S,12R,13S,14S)-14-hydroxy-3,22-dimethoxy-12,13-dimethyl-5,7,18,20-tetraoxapentacyclo[13.7.0.02,10.04,8.017,21]docosa-1(22),2,4(8),9,15,17(21)-hexaen-11-yl] acetate
SMILES (Canonical) CC1C(C(C2=CC3=C(C(=C2C4=C(C5=C(C=C4C1O)OCO5)OC)OC)OCO3)OC(=O)C)C
SMILES (Isomeric) C[C@H]1[C@H]([C@@H](C2=CC3=C(C(=C2C4=C(C5=C(C=C4[C@H]1O)OCO5)OC)OC)OCO3)OC(=O)C)C
InChI InChI=1S/C24H26O9/c1-10-11(2)20(33-12(3)25)14-7-16-22(32-9-30-16)24(28-5)18(14)17-13(19(10)26)6-15-21(23(17)27-4)31-8-29-15/h6-7,10-11,19-20,26H,8-9H2,1-5H3/t10-,11+,19-,20-/m0/s1
InChI Key RUJHQOHNFCOAFM-VSBNPSRXSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C24H26O9
Molecular Weight 458.50 g/mol
Exact Mass 458.15768240 g/mol
Topological Polar Surface Area (TPSA) 102.00 Ų
XlogP 3.40

Synonyms

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((11S,12R,13S,14S)-14-hydroxy-3,22-dimethoxy-12,13-dimethyl-5,7,18,20-tetraoxapentacyclo(13.7.0.02,10.04,8.017,21)docosa-1(22),2,4(8),9,15,17(21)-hexaen-11-yl) acetate
[(11S,12R,13S,14S)-14-hydroxy-3,22-dimethoxy-12,13-dimethyl-5,7,18,20-tetraoxapentacyclo[13.7.0.02,10.04,8.017,21]docosa-1(22),2,4(8),9,15,17(21)-hexaen-11-yl] acetate
RefChem:150731
1013633-20-9
CHEMBL457477

2D Structure

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2D Structure of Kadangustin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.93% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.91% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.65% 94.45%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 96.63% 96.77%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.70% 86.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.77% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.44% 85.14%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.37% 92.62%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 87.03% 95.89%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 86.41% 96.95%
CHEMBL340 P08684 Cytochrome P450 3A4 86.25% 91.19%
CHEMBL253 P34972 Cannabinoid CB2 receptor 86.24% 97.25%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 85.75% 82.67%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 85.15% 94.80%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 84.06% 97.21%
CHEMBL3060 Q9Y345 Glycine transporter 2 83.83% 99.17%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 83.59% 80.96%
CHEMBL2581 P07339 Cathepsin D 82.26% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.04% 95.56%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.46% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Kadsura angustifolia

Cross-Links

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PubChem 24862636
LOTUS LTS0081204
wikiData Q105245648