Excoecarin F

Details

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Internal ID f041ac82-f1a5-4ef0-b13f-b441bdcb77f1
Taxonomy Organoheterocyclic compounds > Benzopyrans
IUPAC Name 2-[(2R,4aS,5R,6S,8aS)-5-(carboxymethyl)-2-[(1S)-2-chloro-1-hydroxyethyl]-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydrochromen-6-yl]-2-methylpropanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H33ClO6/c1-17(2,16(25)26)12-6-8-19(4)13(18(12,3)10-15(23)24)7-9-20(5,27-19)14(22)11-21/h12-14,22H,6-11H2,1-5H3,(H,23,24)(H,25,26)/t12-,13+,14-,18-,19+,20-/m1/s1
InChI Key BKRUBSVLDZLXMF-CMKQGYTDSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C20H33ClO6
Molecular Weight 404.90 g/mol
Exact Mass 404.1965665 g/mol
Topological Polar Surface Area (TPSA) 104.00 Ų
XlogP 2.60

Synonyms

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2-((2R,4aS,5R,6S,8aS)-5-(carboxymethyl)-2-((1S)-2-chloro-1-hydroxyethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydrochromen-6-yl)-2-methylpropanoic acid
2-[(2R,4As,5R,6S,8aS)-5-(carboxymethyl)-2-[(1S)-2-chloro-1-hydroxyethyl]-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydrochromen-6-yl]-2-methylpropanoic acid
RefChem:139740

2D Structure

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2D Structure of Excoecarin F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 99.09% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.44% 91.11%
CHEMBL2581 P07339 Cathepsin D 92.58% 98.95%
CHEMBL218 P21554 Cannabinoid CB1 receptor 90.02% 96.61%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 88.43% 96.77%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 88.15% 96.09%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 85.77% 93.04%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.57% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.88% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.08% 97.09%
CHEMBL340 P08684 Cytochrome P450 3A4 80.50% 91.19%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 80.27% 85.14%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Excoecaria agallocha

Cross-Links

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PubChem 15372475
LOTUS LTS0043086
wikiData Q104937754