Dichrostachine N

Details

Top
Internal ID b9ad0d02-2ea7-4d87-8f8a-21d115d520c8
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids
IUPAC Name (4aR,8R,8aS)-8-[[(1S,4aS,7S,8aS)-1,7-dihydroxy-5,5,8a-trimethyl-2-methylidene-3-oxo-4a,6,7,8-tetrahydro-4H-naphthalen-1-yl]methyl]-8a-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-3-methoxy-7-methyl-5,8-dihydro-4aH-naphthalene-1,4-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C37H42O10/c1-18-8-9-22-33(43)28(46-7)14-30(42)37(22,31-13-26(41)32-25(40)10-21(45-6)11-27(32)47-31)23(18)17-36(44)19(2)24(39)12-29-34(3,4)15-20(38)16-35(29,36)5/h8,10-11,13-14,20,22-23,29,38,40,44H,2,9,12,15-17H2,1,3-7H3/t20-,22-,23+,29-,35-,36+,37-/m0/s1
InChI Key FMZMUHWPKKFIMW-LDCCHIFSSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C37H42O10
Molecular Weight 646.70 g/mol
Exact Mass 646.27779753 g/mol
Topological Polar Surface Area (TPSA) 157.00 Ų
XlogP 3.50

Synonyms

Top
(4aR,8R,8aS)-8-(((1S,4aS,7S,8aS)-1,7-dihydroxy-5,5,8a-trimethyl-2-methylidene-3-oxo-4a,6,7,8-tetrahydro-4H-naphthalen-1-yl)methyl)-8a-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-3-methoxy-7-methyl-5,8-dihydro-4aH-naphthalene-1,4-dione
(4aR,8R,8aS)-8-[[(1S,4aS,7S,8aS)-1,7-dihydroxy-5,5,8a-trimethyl-2-methylidene-3-oxo-4a,6,7,8-tetrahydro-4H-naphthalen-1-yl]methyl]-8a-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-3-methoxy-7-methyl-5,8-dihydro-4aH-naphthalene-1,4-dione
RefChem:133152
CHEMBL1077626

2D Structure

Top
2D Structure of Dichrostachine N

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.55% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 98.08% 85.14%
CHEMBL3192 Q9BY41 Histone deacetylase 8 96.14% 93.99%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.81% 94.45%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 95.79% 94.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.44% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.71% 97.09%
CHEMBL2581 P07339 Cathepsin D 92.30% 98.95%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.04% 89.00%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 88.58% 96.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.67% 86.33%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 87.57% 99.15%
CHEMBL4208 P20618 Proteasome component C5 87.23% 90.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 87.04% 92.94%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.48% 99.17%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.45% 95.89%
CHEMBL3922 P50579 Methionine aminopeptidase 2 86.40% 97.28%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.13% 97.14%
CHEMBL3194 P02766 Transthyretin 84.05% 90.71%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 83.64% 96.09%
CHEMBL340 P08684 Cytochrome P450 3A4 82.76% 91.19%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.73% 99.23%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.12% 91.07%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.51% 90.71%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Dichrostachys cinerea

Cross-Links

Top
PubChem 44557284
LOTUS LTS0077331
wikiData Q104998163