Desulfated holothurin A

Details

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Internal ID 46b8cdc1-c644-41c8-b7c3-d78ff3821145
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Terpene glycosides > Triterpene glycosides > Triterpene saponins
IUPAC Name 16-[3-[5-[4-[3,5-dihydroxy-6-(hydroxymethyl)-4-methoxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-methyloxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxy-6-(5,5-dimethyloxolan-2-yl)-5,10-dihydroxy-2,6,13,17,17-pentamethyl-7-oxapentacyclo[10.8.0.02,9.05,9.013,18]icos-11-en-8-one
SMILES (Canonical) CC1C(C(C(C(O1)OC2C(C(COC2OC3CCC4(C(C3(C)C)CCC5C4=CC(C67C5(CCC6(C(OC7=O)(C)C8CCC(O8)(C)C)O)C)O)C)O)O)O)O)OC9C(C(C(C(O9)CO)O)OC1C(C(C(C(O1)CO)O)OC)O)O
SMILES (Isomeric) CC1C(C(C(C(O1)OC2C(C(COC2OC3CCC4(C(C3(C)C)CCC5C4=CC(C67C5(CCC6(C(OC7=O)(C)C8CCC(O8)(C)C)O)C)O)C)O)O)O)O)OC9C(C(C(C(O9)CO)O)OC1C(C(C(C(O1)CO)O)OC)O)O
InChI InChI=1S/C54H86O24/c1-22-39(74-45-38(65)41(34(61)27(20-56)72-45)75-44-37(64)40(68-9)33(60)26(19-55)71-44)35(62)36(63)43(70-22)76-42-32(59)25(57)21-69-46(42)73-30-13-15-50(6)24-18-29(58)54-47(66)78-52(8,31-12-14-48(2,3)77-31)53(54,67)17-16-51(54,7)23(24)10-11-28(50)49(30,4)5/h18,22-23,25-46,55-65,67H,10-17,19-21H2,1-9H3
InChI Key SZYNJWAQHXVDTN-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C54H86O24
Molecular Weight 1119.20 g/mol
Exact Mass 1118.55090361 g/mol
Topological Polar Surface Area (TPSA) 361.00 Ų
XlogP -1.80

Synonyms

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Holothurin A, desulfo-
11060-73-4

2D Structure

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2D Structure of Desulfated holothurin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.72% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.53% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.51% 96.09%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 93.47% 94.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.15% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.31% 86.33%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 92.19% 96.77%
CHEMBL3714130 P46095 G-protein coupled receptor 6 91.40% 97.36%
CHEMBL241 Q14432 Phosphodiesterase 3A 89.98% 92.94%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.97% 97.25%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.04% 95.89%
CHEMBL226 P30542 Adenosine A1 receptor 88.52% 95.93%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 87.95% 86.92%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.83% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.38% 97.09%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 86.10% 95.83%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 84.50% 91.24%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.41% 92.62%
CHEMBL4208 P20618 Proteasome component C5 82.93% 90.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.02% 97.14%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 81.38% 85.14%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.99% 95.89%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 80.63% 97.33%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.42% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Ziziphus mucronata

Cross-Links

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PubChem 3038027
LOTUS LTS0084996
wikiData Q105361849