Daphnilongeranin C

Details

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Internal ID b5137842-cb09-46eb-987e-71eed424d9da
Taxonomy Alkaloids and derivatives > Yuzurimine-type alkaloids
IUPAC Name (1R,2S,3R,5R,6S,10S,16R,17R)-2,6-dimethyl-20-oxo-8-azahexacyclo[11.5.1.11,5.02,10.03,8.016,19]icos-13(19)-ene-17-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H29NO3/c1-11-9-23-10-13-5-3-12-4-6-14-16(20(25)26)8-22(18(12)14)19(24)15(11)7-17(23)21(13,22)2/h11,13-17H,3-10H2,1-2H3,(H,25,26)/t11-,13-,14-,15-,16-,17-,21-,22+/m1/s1
InChI Key JOODVMXQKVRURX-ROEHNZSPSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C22H29NO3
Molecular Weight 355.50 g/mol
Exact Mass 355.21474379 g/mol
Topological Polar Surface Area (TPSA) 57.60 Ų
XlogP -0.40

Synonyms

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750649-07-1
(1r,2s,3r,5r,6s,10s,16r,17r)-2,6-dimethyl-20-oxo-8-azahexacyclo[11.5.1.11,5.02,10.03,8.016,19]icos-13(19)-ene-17-carboxylic Acid
daphnilongeranins C
Daphnilongeranine C; De-N-oxide-calyciphylline A
AKOS032961626
FS-9011
InChI=1/C22H29NO3/c1-11-9-23-10-13-5-3-12-4-6-14-16(20(25)26)8-22(18(12)14)19(24)15(11)7-17(23)21(13,22)2/h11,13-17H,3-10H2,1-2H3,(H,25,26)/t11?,13?,14-,15?,16?,17-,21-,22+/m1/s

2D Structure

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2D Structure of Daphnilongeranin C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.58% 96.09%
CHEMBL2581 P07339 Cathepsin D 95.27% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.89% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.50% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 88.48% 97.25%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.35% 95.56%
CHEMBL340 P08684 Cytochrome P450 3A4 87.93% 91.19%
CHEMBL5255 O00206 Toll-like receptor 4 86.40% 92.50%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 84.74% 94.78%
CHEMBL1951 P21397 Monoamine oxidase A 84.67% 91.49%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.95% 82.69%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 81.79% 93.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.96% 99.23%
CHEMBL4040 P28482 MAP kinase ERK2 80.46% 83.82%
CHEMBL1293249 Q13887 Kruppel-like factor 5 80.33% 86.33%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Daphniphyllum himalayense

Cross-Links

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PubChem 11501289
LOTUS LTS0118112
wikiData Q105132445