Cordatolide E

Details

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Internal ID 8d438dfc-d586-41b6-8834-878cbd832a77
Taxonomy Phenylpropanoids and polyketides > Coumarins and derivatives > Pyranocoumarins > Angular pyranocoumarins
IUPAC Name 5-hydroxy-6-(3-hydroxy-2-methylbutanoyl)-2,2,10-trimethyl-9,10-dihydropyrano[2,3-f]chromen-8-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H24O6/c1-9-8-13(22)25-19-14(9)18-12(6-7-20(4,5)26-18)17(24)15(19)16(23)10(2)11(3)21/h6-7,9-11,21,24H,8H2,1-5H3
InChI Key YBTZYMZAMUEVJB-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C20H24O6
Molecular Weight 360.40 g/mol
Exact Mass 360.15728848 g/mol
Topological Polar Surface Area (TPSA) 93.10 Ų
XlogP 3.00

Synonyms

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5-hydroxy-6-(3-hydroxy-2-methylbutanoyl)-2,2,10-trimethyl-9,10-dihydropyrano[2,3-f]chromen-8-one
5-hydroxy-6-(3-hydroxy-2-methylbutanoyl)-2,2,10-trimethyl-9,10-dihydropyrano(2,3-f)chromen-8-one
RefChem:127965
CHEMBL462029
NSC692295
NSC-692295
5-hydroxy-6-(3-hydroxy-2-methyl-butanoyl)-2,2,10-trimethyl-9,10-dihydropyrano[2,3-f]chromen-8-one

2D Structure

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2D Structure of Cordatolide E

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.04% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.83% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.74% 85.14%
CHEMBL2581 P07339 Cathepsin D 94.31% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.40% 94.45%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.68% 97.25%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.01% 89.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 88.33% 90.71%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.79% 99.23%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.97% 97.09%
CHEMBL4208 P20618 Proteasome component C5 86.67% 90.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 85.69% 93.56%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 84.59% 95.56%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 81.53% 95.71%
CHEMBL2535 P11166 Glucose transporter 80.30% 98.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Calophyllum lanigerum

Cross-Links

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PubChem 467235
NPASS NPC474108
ChEMBL CHEMBL462029
LOTUS LTS0135741
wikiData Q105346055