Aristophyllide C

Details

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Internal ID 6ac7be46-6b10-4083-a06b-adf080d5740e
Taxonomy Benzenoids > Phenanthrenes and derivatives > Aristolochic acids and derivatives
IUPAC Name [(2S)-1-[(5R,6R)-5-ethenyl-5-methyl-6-(3-oxoprop-1-en-2-yl)cyclohexen-1-yl]propan-2-yl] 6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H29NO7/c1-5-31(4)12-8-10-21(28(31)18(2)16-33)13-19(3)39-30(34)23-15-25-29(38-17-37-25)27-22-11-7-6-9-20(22)14-24(26(23)27)32(35)36/h5-7,9-11,14-16,19,28H,1-2,8,12-13,17H2,3-4H3/t19-,28+,31-/m0/s1
InChI Key IIBMSRRBRIHDMP-GOVLGDJKSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C31H29NO7
Molecular Weight 527.60 g/mol
Exact Mass 527.19440226 g/mol
Topological Polar Surface Area (TPSA) 108.00 Ų
XlogP 7.20

Synonyms

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((2S)-1-((5R,6R)-5-ethenyl-5-methyl-6-(3-oxoprop-1-en-2-yl)cyclohexen-1-yl)propan-2-yl) 6-nitronaphtho(2,1-g)(1,3)benzodioxole-5-carboxylate
[(2S)-1-[(5R,6R)-5-ethenyl-5-methyl-6-(3-oxoprop-1-en-2-yl)cyclohexen-1-yl]propan-2-yl] 6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylate
RefChem:114067
221148-62-5
CHEMBL454825

2D Structure

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2D Structure of Aristophyllide C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL240 Q12809 HERG 99.95% 89.76%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.97% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.91% 94.45%
CHEMBL2581 P07339 Cathepsin D 97.15% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.88% 96.09%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 95.29% 96.77%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 95.16% 92.62%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.61% 86.33%
CHEMBL3902 P09211 Glutathione S-transferase Pi 92.16% 93.81%
CHEMBL3401 O75469 Pregnane X receptor 92.13% 94.73%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.50% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.30% 89.00%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 89.21% 95.71%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 86.83% 95.50%
CHEMBL221 P23219 Cyclooxygenase-1 86.73% 90.17%
CHEMBL5028 O14672 ADAM10 86.68% 97.50%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.65% 99.23%
CHEMBL4208 P20618 Proteasome component C5 83.50% 90.00%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 83.40% 80.96%
CHEMBL4072 P07858 Cathepsin B 82.95% 93.67%
CHEMBL2716 Q8WUI4 Histone deacetylase 7 81.30% 89.44%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 80.98% 85.30%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 80.89% 96.67%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 80.73% 94.80%
CHEMBL340 P08684 Cytochrome P450 3A4 80.02% 91.19%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Aristolochia kaempferi

Cross-Links

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PubChem 10839881
LOTUS LTS0083152
wikiData Q105113374