Alstonic acid A

Details

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Internal ID c0b47429-f247-4da9-8299-ec5ebc12fc23
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Oxosteroids > 20-oxosteroids
IUPAC Name 2-[(3R,4S,8S,9S,13R,14R,17R)-4,8,9,13-tetramethyl-3-(2-methyl-1-oxopropan-2-yl)-17-propan-2-yl-2,3,6,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-4-yl]acetic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H48O3/c1-19(2)20-9-12-24-27(20,5)15-16-29(7)22-10-11-23(26(3,4)18-31)28(6,17-25(32)33)21(22)13-14-30(24,29)8/h18-20,23-24H,9-17H2,1-8H3,(H,32,33)/t20-,23+,24-,27-,28-,29-,30+/m1/s1
InChI Key WODHWLGTVYKRQF-PWWKQHFHSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C30H48O3
Molecular Weight 456.70 g/mol
Exact Mass 456.36034539 g/mol
Topological Polar Surface Area (TPSA) 54.40 Ų
XlogP 7.50

Synonyms

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1159579-44-8
19-Norpregn-5(10)-ene-4-acetic acid, 3-(1,1-dimethyl-2-oxoethyl)-4,8,9,20-tetramethyl-, (3alpha,4beta)-
2-[(3R,4S,8S,9S,13R,14R,17R)-4,8,9,13-tetramethyl-3-(2-methyl-1-oxopropan-2-yl)-17-propan-2-yl-2,3,6,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-4-yl]acetic acid
AKOS032962006
FS-10183
CS-0023439
19-Norpregn-5(10)-ene-4-acetic acid, 3-(1,1-dimethyl-2-oxoethyl)-4,8,9,20-tetramethyl-, (3|A,4|A)-

2D Structure

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2D Structure of Alstonic acid A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.74% 97.25%
CHEMBL2581 P07339 Cathepsin D 95.31% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.30% 96.09%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 94.58% 96.38%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 93.98% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.59% 95.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.51% 91.11%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 91.31% 93.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.94% 94.45%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 89.83% 96.77%
CHEMBL284 P27487 Dipeptidyl peptidase IV 87.69% 95.69%
CHEMBL340 P08684 Cytochrome P450 3A4 86.22% 91.19%
CHEMBL2179 P04062 Beta-glucocerebrosidase 86.15% 85.31%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.50% 95.89%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 82.36% 100.00%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 82.16% 91.71%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 82.03% 95.89%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.70% 100.00%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.37% 94.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.26% 89.00%
CHEMBL5028 O14672 ADAM10 81.14% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Alstonia scholaris

Cross-Links

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PubChem 91895416
LOTUS LTS0044380
wikiData Q104400432