Ajugamarin A1 Chlorohydrin

Details

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Internal ID 4af6dcdf-a531-46c0-ac62-0caac8593fc6
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Terpene lactones > Diterpene lactones
IUPAC Name [(1R,4R,4aR,5S,7R,8S,8aR)-5-acetyloxy-4a-(acetyloxymethyl)-4-(chloromethyl)-4-hydroxy-8-[(2S)-2-hydroxy-2-(5-oxo-2H-furan-3-yl)ethyl]-7,8-dimethyl-2,3,5,6,7,8a-hexahydro-1H-naphthalen-1-yl] (E)-2-methylbut-2-enoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C29H41ClO10/c1-7-16(2)26(35)40-22-8-9-28(36,14-30)29(15-38-18(4)31)23(39-19(5)32)10-17(3)27(6,25(22)29)12-21(33)20-11-24(34)37-13-20/h7,11,17,21-23,25,33,36H,8-10,12-15H2,1-6H3/b16-7+/t17-,21+,22-,23+,25-,27+,28+,29-/m1/s1
InChI Key CWWDVANTGWQWKM-CJARLIFWSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C29H41ClO10
Molecular Weight 585.10 g/mol
Exact Mass 584.2388252 g/mol
Topological Polar Surface Area (TPSA) 146.00 Ų
XlogP 2.50

Synonyms

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CHEBI:69866
CHEMBL1813855
Q27138207
(1R,4R,4aR,5S,7R,8S,8aR)-5-(acetyloxy)-4a-[(acetyloxy)methyl]-4-(chloromethyl)-4-hydroxy-8-[(2S)-2-hydroxy-2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl]-7,8-dimethyldecahydronaphthalen-1-yl (2E)-2-methylbut-2-enoate
[(1R,4R,4aR,5S,7R,8S,8aR)-5-acetyloxy-4a-(acetyloxymethyl)-4-(chloromethyl)-4-hydroxy-8-[(2S)-2-hydroxy-2-(5-oxo-2H-furan-3-yl)ethyl]-7,8-dimethyl-2,3,5,6,7,8a-hexahydro-1H-naphthalen-1-yl] (E)-2-methylbut-2-enoate

2D Structure

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2D Structure of Ajugamarin A1 Chlorohydrin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.92% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.05% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.65% 94.45%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.47% 97.25%
CHEMBL221 P23219 Cyclooxygenase-1 94.97% 90.17%
CHEMBL2581 P07339 Cathepsin D 94.49% 98.95%
CHEMBL1994 P08235 Mineralocorticoid receptor 90.55% 100.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.51% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.27% 97.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.20% 86.33%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 87.83% 82.69%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.98% 95.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.85% 95.89%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 83.38% 94.80%
CHEMBL4227 P25090 Lipoxin A4 receptor 83.34% 100.00%
CHEMBL340 P08684 Cytochrome P450 3A4 82.71% 91.19%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.35% 92.62%
CHEMBL2782 P35610 Acyl coenzyme A:cholesterol acyltransferase 1 82.30% 91.65%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.38% 97.14%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.28% 91.07%
CHEMBL3922 P50579 Methionine aminopeptidase 2 80.69% 97.28%
CHEMBL2413 P32246 C-C chemokine receptor type 1 80.09% 89.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Ajuga ciliata

Cross-Links

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PubChem 21626547
LOTUS LTS0121662
wikiData Q27138207