(ADMAdda5)microcystin-LR

Details

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Internal ID fb9f1388-7d58-417b-a749-2843e48ca87a
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (5R,8S,11R,12S,15S,18S,19S,22R)-18-[(1E,3E,5S,6S)-6-acetyloxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-15-[3-(diaminomethylideneamino)propyl]-1,5,12,19-tetramethyl-2-methylidene-8-(2-methylpropyl)-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C50H74N10O13/c1-26(2)23-38-47(68)59-41(49(71)72)30(6)43(64)56-36(17-14-22-53-50(51)52)46(67)55-35(19-18-27(3)24-28(4)39(73-33(9)61)25-34-15-12-11-13-16-34)29(5)42(63)57-37(48(69)70)20-21-40(62)60(10)32(8)45(66)54-31(7)44(65)58-38/h11-13,15-16,18-19,24,26,28-31,35-39,41H,8,14,17,20-23,25H2,1-7,9-10H3,(H,54,66)(H,55,67)(H,56,64)(H,57,63)(H,58,65)(H,59,68)(H,69,70)(H,71,72)(H4,51,52,53)/b19-18+,27-24+/t28-,29-,30-,31+,35-,36-,37+,38-,39-,41+/m0/s1
InChI Key DDMJZWZMKZNCTP-RASTYGMGSA-N
Popularity 6 references in papers

Physical and Chemical Properties

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Molecular Formula C50H74N10O13
Molecular Weight 1023.20 g/mol
Exact Mass 1022.54368245 g/mol
Topological Polar Surface Area (TPSA) 360.00 Ų
XlogP 2.30

Synonyms

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(ADMAdda5)microcystin-LR
DTXSID501046973

2D Structure

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2D Structure of (ADMAdda5)microcystin-LR

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4040 P28482 MAP kinase ERK2 99.96% 83.82%
CHEMBL2581 P07339 Cathepsin D 99.85% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.34% 96.09%
CHEMBL4072 P07858 Cathepsin B 97.82% 93.67%
CHEMBL3837 P07711 Cathepsin L 97.74% 96.61%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.62% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 95.25% 86.33%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.67% 91.11%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 94.44% 97.64%
CHEMBL3060 Q9Y345 Glycine transporter 2 93.81% 99.17%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.37% 94.45%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 90.12% 95.89%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 88.79% 91.71%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 88.16% 90.71%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.65% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.90% 97.09%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 85.88% 93.00%
CHEMBL1255126 O15151 Protein Mdm4 85.63% 90.20%
CHEMBL4644 P41968 Melanocortin receptor 3 82.32% 99.52%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 82.20% 96.47%
CHEMBL2535 P11166 Glucose transporter 82.08% 98.75%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 81.39% 100.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.46% 90.08%
CHEMBL1937 Q92769 Histone deacetylase 2 80.46% 94.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Alnus pendula
Alnus serrulatoides
Alnus sieboldiana

Cross-Links

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PubChem 14752800
LOTUS LTS0240195
wikiData Q105159391