7(8)-dihydroisojusticidin B

Details

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Internal ID 7c35278e-ac7a-4a56-9068-f382ce7bae1d
Taxonomy Lignans, neolignans and related compounds > Lignan lactones
IUPAC Name 4-(1,3-benzodioxol-5-yl)-5,6-dimethoxy-9,9a-dihydro-1H-benzo[f][2]benzofuran-3-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H18O6/c1-23-15-6-4-11-7-13-9-25-21(22)19(13)17(18(11)20(15)24-2)12-3-5-14-16(8-12)27-10-26-14/h3-6,8,13H,7,9-10H2,1-2H3
InChI Key CZEUIACCFFFCLU-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C21H18O6
Molecular Weight 366.40 g/mol
Exact Mass 366.11033829 g/mol
Topological Polar Surface Area (TPSA) 63.20 Ų
XlogP 3.10

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 7(8)-dihydroisojusticidin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.96% 94.45%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 95.62% 80.96%
CHEMBL1293249 Q13887 Kruppel-like factor 5 95.62% 86.33%
CHEMBL240 Q12809 HERG 93.62% 89.76%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.15% 91.11%
CHEMBL2581 P07339 Cathepsin D 92.89% 98.95%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 92.64% 94.80%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.43% 95.56%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.37% 94.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 90.59% 92.62%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 88.99% 97.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 88.88% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 88.54% 85.14%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 88.17% 96.77%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 87.63% 96.00%
CHEMBL4306 P22460 Voltage-gated potassium channel subunit Kv1.5 87.37% 94.03%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.51% 95.89%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 83.20% 95.78%
CHEMBL3060 Q9Y345 Glycine transporter 2 83.09% 99.17%
CHEMBL4247 Q9UM73 ALK tyrosine kinase receptor 82.68% 96.86%
CHEMBL2535 P11166 Glucose transporter 82.55% 98.75%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 82.26% 96.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.44% 100.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.26% 97.09%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 80.63% 82.67%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 80.59% 96.00%
CHEMBL4302 P08183 P-glycoprotein 1 80.35% 92.98%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.30% 89.00%
CHEMBL1951 P21397 Monoamine oxidase A 80.04% 91.49%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 80.01% 93.40%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Linum perenne

Cross-Links

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PubChem 134820205
LOTUS LTS0195736
wikiData Q104972748