2,3,4,5,2',6'-Hexamethoxy-3',4'-methylenedioxychalcone

Details

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Internal ID 0fc5c6e6-a333-4f77-91b3-d7958303f75c
Taxonomy Phenylpropanoids and polyketides > Cinnamic acids and derivatives
IUPAC Name (E)-1-(4,6-dimethoxy-1,3-benzodioxol-5-yl)-3-(2,3,4,5-tetramethoxyphenyl)prop-2-en-1-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H24O9/c1-24-14-10-16-20(31-11-30-16)21(28-5)17(14)13(23)8-7-12-9-15(25-2)19(27-4)22(29-6)18(12)26-3/h7-10H,11H2,1-6H3/b8-7+
InChI Key QSWHICAMOUHPJP-BQYQJAHWSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C22H24O9
Molecular Weight 432.40 g/mol
Exact Mass 432.14203234 g/mol
Topological Polar Surface Area (TPSA) 90.90 Ų
XlogP 3.30

Synonyms

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(E)-1-(4,6-dimethoxy-1,3-benzodioxol-5-yl)-3-(2,3,4,5-tetramethoxyphenyl)prop-2-en-1-one
RefChem:81218
121697-06-1
CHEBI:196403
LMPK12120355

2D Structure

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2D Structure of 2,3,4,5,2',6'-Hexamethoxy-3',4'-methylenedioxychalcone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.92% 91.11%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 96.41% 96.77%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.50% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.92% 94.45%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 92.57% 96.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.89% 86.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.82% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.96% 89.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.95% 92.62%
CHEMBL3060 Q9Y345 Glycine transporter 2 85.94% 99.17%
CHEMBL2413 P32246 C-C chemokine receptor type 1 85.80% 89.50%
CHEMBL4208 P20618 Proteasome component C5 85.57% 90.00%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 83.30% 82.67%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.22% 95.50%
CHEMBL3401 O75469 Pregnane X receptor 81.51% 94.73%
CHEMBL2535 P11166 Glucose transporter 80.20% 98.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Scutellaria indica

Cross-Links

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PubChem 14332443
LOTUS LTS0076973
wikiData Q76423741