2,2'-Dihydroxy-3,4,5,6'-tetramethoxy-4',5'-methylenedioxychalcone

Details

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Internal ID dcc220d1-3fd8-4df0-b74e-42ee5aa31df5
Taxonomy Phenylpropanoids and polyketides > Linear 1,3-diarylpropanoids > Chalcones and dihydrochalcones > 2-Hydroxychalcones
IUPAC Name 1-(6-hydroxy-4-methoxy-1,3-benzodioxol-5-yl)-3-(2-hydroxy-3,4,5-trimethoxyphenyl)prop-2-en-1-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H20O9/c1-24-13-7-10(16(23)20(27-4)17(13)25-2)5-6-11(21)15-12(22)8-14-18(19(15)26-3)29-9-28-14/h5-8,22-23H,9H2,1-4H3
InChI Key GHJIQGPMSLGWQW-UHFFFAOYSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C20H20O9
Molecular Weight 404.40 g/mol
Exact Mass 404.11073221 g/mol
Topological Polar Surface Area (TPSA) 113.00 Ų
XlogP 3.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 2,2'-Dihydroxy-3,4,5,6'-tetramethoxy-4',5'-methylenedioxychalcone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.23% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.37% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.41% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.18% 95.56%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 91.68% 96.00%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 91.04% 96.77%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.03% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.82% 86.33%
CHEMBL3194 P02766 Transthyretin 90.10% 90.71%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 89.15% 85.30%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.69% 99.17%
CHEMBL4208 P20618 Proteasome component C5 86.04% 90.00%
CHEMBL1163101 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 85.42% 98.11%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 84.35% 95.50%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.84% 92.62%
CHEMBL2413 P32246 C-C chemokine receptor type 1 83.65% 89.50%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 82.84% 82.67%
CHEMBL3401 O75469 Pregnane X receptor 81.66% 94.73%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 81.02% 94.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Scutellaria indica
Taraxacum officinale

Cross-Links

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PubChem 129829857
LOTUS LTS0125786
wikiData Q105379916