Aconitan-6-one, 20-ethyl-10-hydroxy-1,14,16-trimethoxy-4-methyl-7,8-(methylenebis(oxy))-, (1alpha,14alpha,16beta)-

Details

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Internal ID a1330700-d611-4ffd-81b4-20ae24a2e465
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Aconitane-type diterpenoid alkaloids
IUPAC Name 14-ethyl-2-hydroxy-4,6,19-trimethoxy-16-methyl-9,11-dioxa-14-azaheptacyclo[10.7.2.12,5.01,13.03,8.08,12.016,20]docosan-21-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H37NO7/c1-6-26-11-21(2)8-7-15(30-4)24-18(21)19(27)25(20(24)26)23(32-12-33-25)10-14(29-3)13-9-22(24,28)17(23)16(13)31-5/h13-18,20,28H,6-12H2,1-5H3
InChI Key TXYJTEYUHCHSBK-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C25H37NO7
Molecular Weight 463.60 g/mol
Exact Mass 463.25700252 g/mol
Topological Polar Surface Area (TPSA) 86.70 Ų
XlogP 0.10

Synonyms

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Aconitan-6-one, 20-ethyl-10-hydroxy-1,14,16-trimethoxy-4-methyl-7,8-(methylenebis(oxy))-, (1alpha,14alpha,16beta)-

2D Structure

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2D Structure of Aconitan-6-one, 20-ethyl-10-hydroxy-1,14,16-trimethoxy-4-methyl-7,8-(methylenebis(oxy))-, (1alpha,14alpha,16beta)-

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.17% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.17% 97.25%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.02% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.40% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.46% 97.09%
CHEMBL2581 P07339 Cathepsin D 91.08% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.47% 86.33%
CHEMBL3922 P50579 Methionine aminopeptidase 2 89.27% 97.28%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 88.31% 85.14%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 86.41% 94.00%
CHEMBL1871 P10275 Androgen Receptor 85.28% 96.43%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.28% 97.14%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 84.53% 92.62%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 83.92% 94.78%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 83.29% 95.17%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.70% 95.89%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 82.26% 94.33%
CHEMBL241 Q14432 Phosphodiesterase 3A 80.96% 92.94%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.75% 99.23%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.71% 100.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 80.68% 93.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Delphinium barbeyi

Cross-Links

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PubChem 182686
LOTUS LTS0086125
wikiData Q105267165