1,8-Dihydroxy-3-methoxy-6-methyl-2-(2,5,10-trihydroxy-7-methoxy-2-methyl-4-oxo-1,3-dihydroanthracen-9-yl)anthracene-9,10-dione

Details

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Internal ID ba57cb07-c18e-4c71-92aa-32b12009c47c
Taxonomy Lignans, neolignans and related compounds > Arylnaphthalene lignans
IUPAC Name 1,8-dihydroxy-3-methoxy-6-methyl-2-(2,5,10-trihydroxy-7-methoxy-2-methyl-4-oxo-1,3-dihydroanthracen-9-yl)anthracene-9,10-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H26O10/c1-12-5-15-24(18(33)6-12)30(38)26-16(28(15)36)9-21(42-4)27(31(26)39)22-14-7-13(41-3)8-19(34)23(14)29(37)25-17(22)10-32(2,40)11-20(25)35/h5-9,33-34,37,39-40H,10-11H2,1-4H3
InChI Key LKMSWRVEGLONJV-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C32H26O10
Molecular Weight 570.50 g/mol
Exact Mass 570.15259702 g/mol
Topological Polar Surface Area (TPSA) 171.00 Ų
XlogP 5.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 1,8-Dihydroxy-3-methoxy-6-methyl-2-(2,5,10-trihydroxy-7-methoxy-2-methyl-4-oxo-1,3-dihydroanthracen-9-yl)anthracene-9,10-dione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.55% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.89% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.07% 85.14%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 96.18% 99.15%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 96.05% 96.21%
CHEMBL1806 P11388 DNA topoisomerase II alpha 95.58% 89.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 94.60% 99.23%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 93.79% 94.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.27% 96.09%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 92.58% 92.68%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 92.40% 96.77%
CHEMBL4208 P20618 Proteasome component C5 92.18% 90.00%
CHEMBL2581 P07339 Cathepsin D 92.07% 98.95%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 91.61% 91.79%
CHEMBL1951 P21397 Monoamine oxidase A 91.01% 91.49%
CHEMBL241 Q14432 Phosphodiesterase 3A 90.85% 92.94%
CHEMBL2535 P11166 Glucose transporter 90.58% 98.75%
CHEMBL240 Q12809 HERG 89.76% 89.76%
CHEMBL2056 P21728 Dopamine D1 receptor 87.19% 91.00%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.72% 91.07%
CHEMBL340 P08684 Cytochrome P450 3A4 86.12% 91.19%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 86.07% 96.67%
CHEMBL1937 Q92769 Histone deacetylase 2 85.64% 94.75%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.50% 94.45%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.32% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.89% 95.89%
CHEMBL1907 P15144 Aminopeptidase N 82.99% 93.31%
CHEMBL5925 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 82.47% 92.38%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.08% 97.14%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Senna multiglandulosa
Senna sophera

Cross-Links

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PubChem 102318018
LOTUS LTS0215960
wikiData Q105153152