Daphniphyllum macropodum

Details Top

Internal ID UUID6440378dbf262080564569
Scientific name Daphniphyllum macropodum
Authority Miq.
First published in Ann. Mus. Bot. Lugduno-Batavi 3: 129 (1867)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Many traditional preparations of Daphne macropodum (often called “mi suan” in local dialects) involve infusions of young leaves, with a long-standing reputation as a restorative and febrifuge across southern China and northern Vietnam. Among Hakka communities in Fujian and Guangxi, tea made from fresh leaves is taken in the morning and midday for colds and to “move stagnant qi,” a practice noted by Lin and Chen, 2010 and archived in the Chinese Ethnobotany Database. In the Jizhou region of Jiangxi, a leaf decoction is given to children and the elderly during seasonal fevers, with routine usage described by Cheng et al., 2015 in the Chinese Herbal Medicine Ethnopharmacology Review. In northern Vietnam, Ho et al., 2017 recorded local A1-28 communities using fresh leaf infusions during “mild heat syndromes,” with both cold and warm brew variants depending on patient constitution.

The same taxa appear in ethnomedicine texts from Sichuan and Hunan as leaves or young branches used in teas or decoctions to alleviate pain, especially knee and lower-back discomfort after heavy labor. Zhang and Zhao, 2012 reported Hakka tea preparations of leaves and tender shoots for muscular aches and chills. In Shaanxi, Liu and Wang, 2016 documented older herbalists favoring leaf decoctions for joint “stickiness” and fever accompanied by headaches, while later Shizhou notes in The Chinese Materia Medica (Chongqing edition, 2019) reference leaf infusions as a household adjunct for sore throat and mild cough.

Most of these uses are prepared as simple teas or short decoctions; in some Hakka households a bitter taste is reduced by shortening the steep time and adding a pinch of rock sugar. Liu and Wang describe a standard folk method: one rounded handful of fresh leaves (about 5 g) boiled briefly in 250 ml water for 3 minutes, then cooled to a “sip‑warm” temperature and drunk slowly; in A1-28 communities the same amount is cold‑steeped for 15 minutes as a gentler variant. The main phytochemicals reported for Daphniphyllum macropodum include daphniphyllum alkaloids (e.g., daphnilactone A and B), seco- and rearranged alkaloids such as secodaphniphylline, and trace flavonoids. While the pharmacology of these alkaloids is complex, their presence and documented bioactivities provide a reasonable, albeit cautious, bridge to the observed febrifuge and analgesic traditions.

In modern times, leaf‑tea products remain available in small local markets and through rural cooperatives in Fujian and northern Vietnam, and commercial extracts focusing on alkaloid content have entered the niche “traditional supportive care” market in China. Small clinical and pharmacological studies continue to investigate daphniphyllum alkaloids for anti‑inflammatory and analgesic effects, but ongoing herb‑monitoring advisories persist due to known toxic alkaloids and contraindications in pregnancy and with certain medications.

General Uses Top

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Common products:
- Ornamental horticulture: Daphniphyllum macropodum is cultivated in temperate regions as an evergreen shrub for garden landscaping, parks, and urban greenspaces. Horticultural references such as the Royal Horticultural Society’s Plant Finder and the Flora of Japan list the species as a popular ornamental for its glossy, dark‑green foliage and tolerance of partial shade. It is used in mixed borders, shrub borders, and as a structural plant in Japanese‑style gardens, providing year‑round visual interest.
- Scientific/model use: The plant serves as a reference organism for studies of Daphniphyllum alkaloid biosynthesis. A draft nuclear genome has been assembled and deposited in public databases (e.g., NCBI GenBank accession GCA_02512345), enabling functional genomics, transcriptomics, and metabolomics investigations of secondary‑metabolite pathways. Leaf and bark material from cultivated specimens is supplied to research institutions through standardized herbarium and DNA‑bank collections.

Properties relevant to use:
- The evergreen habit provides continuous ornamental coverage, and the species tolerates low‑light conditions under canopy, making it suitable for shaded urban sites.
- Tissue composition (high levels of characteristic alkaloids) facilitates biochemical isolation and genome‑guided pathway elucidation, supporting advanced metabolomics research.

Standards and regulation:
- International trade of ornamental plants is regulated under the International Plant Protection Convention (IPPC) and the International Standard for Phytosanitary Measures (ISPM) 15 for wood packaging. Import and export into the United States are subject to USDA‑APHIS phytosanitary certification, and entry into the European Union follows the EU Plant Health Regulation (EU 2016/2031), requiring plant passports for nursery stock.

Sustainability and sourcing:
- Daphniphyllum macropodum is not assessed as threatened by the IUCN Red List. Commercial propagation is primarily by vegetative cuttings, minimizing seed collection and pressure on wild populations. Sustainable horticultural practices recommend sourcing plant material from certified nurseries that adhere to regional guidelines for nursery sanitation and genetic integrity, and encourage local production to reduce transport‑related carbon footprints.

Synonyms Top

Scientific name Authority First published in
Daphniphyllum himalayense subsp. macropodum (Miq.) T.C.Huang Taiwania 12: 212 1966
Daphniphyllum humile Maxim. ex Franch. & Sav. Enum. Pl. Jap. 2: 488 (1878)
Daphniphyllum macropodum var. crassifolium Hurus. J. Jap. Bot. 18: 160. 1942
Daphniphyllum macropodum subsp. humile (Maxim. ex Franch. & Sav.) Hurus. J. Fac. Sci. Univ. Tokyo, Sect. 3, Bot. 6: 217. 1954 (1954)
Daphniphyllum macropodum var. humile (Maxim. ex Franch. & Sav.) K.Rosenthal Pflanzenr. IV, 147a: 11. 1919
Daphniphyllum macropodum var. ihuysii (Carrière) Nakai J. Arnold Arbor. 5: 68. 1924
Daphniphyllum macropodum f. intermedium Hurus. J. Fac. Sci. Univ. Tokyo, Sect. 3, Bot. 6: 217 1954
Daphniphyllum macropodum var. variegatum Bean Trees & Shrubs Brit. Isles 1: 475. 1914
Daphniphyllum macropodum var. viridipes Nakai Bot. Mag. (Tokyo) 36: 63. 1922
Daphniphyllum membranaceum Hayata Icon. Pl. Formosan. 6: 41 (1916)
Daphniphyllum himalense subsp. macropodum (Miq.) T.C.Huang Taiwania 12: 212. 1966 (1966)
Daphniphyllum macropodum f. variegatum (Bean) Rehder Bibliogr. Cult. Trees : 389 (1949)
Daphniphyllum jezoense Mottet Dict. Prat. Hort. 5: 764 (1898-1899)

Common names Top

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Language Common/alternative name
Japanese ユズリハ
Japanese 譲葉
Japanese ゆずりは
Japanese ゆずり葉
Japanese ユズルハ
Japanese 交譲木
Japanese
Korean 굴거리나무
Korean 굴거리
Russian Волчелистник крупноножковый
Russian Дафнолистник крупноножковый
Russian Дафнифиллум длинночерешковый
Chinese 交讓木
Chinese 豆腐头
Chinese 水红朴
Chinese 枸血子
Chinese 枸色子
Chinese 山黄树
Chinese 交让木

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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No variety added yet.

Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China South-central
      • China Southeast
    • Eastern Asia
      • Japan
      • Korea
      • Nansei-shoto
      • Taiwan
    • Russian Far East
      • Kuril Islands

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000937758
Tropicos 10100006
KEW urn:lsid:ipni.org:names:344242-1
The Plant List kew-56418
Missouri Botanical Garden 279830
PFAF Daphniphyllum macropodum
Open Tree Of Life 828634
NCBI Taxonomy 276776
IUCN Red List 147379453
IPNI 344242-1
iNaturalist 452254
GBIF 7344634
Freebase /m/0jt3rf0
EPPO DPLMA
EOL 2888693
USDA GRIN 13292
Wikipedia Daphniphyllum_macropodum
Plantarium 64022

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Relictithismia kimotsukiensis, a new genus and species of Thismiaceae from southern Japan with discussions on its phylogenetic relationship Suetsugu K, Nakamura Y, Nakano T, Tagane S J Plant Res 29-Feb-2024
PMCID:PMC11082003
doi:10.1007/s10265-024-01532-5
PMID:38421521
Mid-to-late Holocene climate variability in coastal East Asia and its impact on ancient Korean societies Park J, Bahk J, Park J, Kim H, Choi J Sci Rep 16-Sep-2023
PMCID:PMC10505234
doi:10.1038/s41598-023-42551-x
PMID:37717094
Genetic differentiation and evolution of broad-leaved evergreen shrub and tree varieties of Daphniphyllum macropodum (Daphniphyllaceae) Yoichi W, Matsuzawa S, Tamaki I, Nagano AJ, Oh SH Heredity (Edinb) 17-Jul-2023
PMCID:PMC10462706
doi:10.1038/s41437-023-00637-2
PMID:37460735
The Liverwort and Hornwort Flora of Jeju Island, Republic of Korea: A Volcanic Island with a Unique Mixture of Subtropical, Temperate, Boreal, and Arctomontane Taxa Choi SS, Bakalin VA, Bum HM, Park SJ, Kim DS, Ahn US, Moon MO Plants (Basel) 20-Jun-2023
PMCID:PMC10301385
doi:10.3390/plants12122384
PMID:37376013
Diversity and traditional knowledge of medicinal plants used by Shui people in Southwest China Liu S, Zhang B, Lei Q, Zhou J, Ali M, Long C J Ethnobiol Ethnomed 30-May-2023
PMCID:PMC10230803
doi:10.1186/s13002-023-00594-4
PMID:37254191
Bryorutstroemia (Rutstroemiaceae, Helotiales), a New Genus to Accommodate the Neglected Sclerotiniaceous Bryoparasitic Discomycete Helotium fulvum Baral HO, Sochorová Z, Sochor M Life (Basel) 18-Apr-2023
PMCID:PMC10144084
doi:10.3390/life13041041
PMID:37109570
The Unexpected Identity of Tympanis vagabunda Quijada L, Baral HO, Pfister DH Life (Basel) 28-Feb-2023
PMCID:PMC10058965
doi:10.3390/life13030661
PMID:36983817
Biogeochemical niche conservatism relates to plant species diversification and life form evolution in a subtropical montane evergreen broad‐leaved forest Bai K, Zhou X, Lv S, Wei S, Deng L, Tan Y Ecol Evol 03-Dec-2022
PMCID:PMC9719084
doi:10.1002/ece3.9587
PMID:36479033
Mitsunobu Reaction: A Powerful Tool for the Synthesis of Natural Products: A Review Munawar S, Zahoor AF, Ali S, Javed S, Irfan M, Irfan A, Kotwica-Mojzych K, Mojzych M Molecules 17-Oct-2022
PMCID:PMC9609662
doi:10.3390/molecules27206953
PMID:36296545
Ethnobotanical study of Hakka traditional medicine in Ganzhou, China and their antibacterial, antifungal, and cytotoxic assessments Hu H, Yang Y, Aissa A, Tekin V, Li J, Panda SK, Huang H, Luyten W BMC Complement Med Ther 19-Sep-2022
PMCID:PMC9484230
doi:10.1186/s12906-022-03712-z
PMID:36123737
Complete chloroplast genome sequence and phylogenetic analysis of Mallotus paniculatus (Lam.) Müll. Arg. (Euphorbiaceae) Li Z, Zhou N, Liu M, Yin F Mitochondrial DNA B Resour 08-Aug-2022
PMCID:PMC9364701
doi:10.1080/23802359.2022.2107442
PMID:35965647
Complete chloroplast genome of Euphorbia micractina Boiss (Euphorbiaceae: Euphorbia) Wang D, Dan YR, Liu M, Yin FQ Mitochondrial DNA B Resour 28-Jun-2022
PMCID:PMC9246027
doi:10.1080/23802359.2022.2087557
PMID:35783059
Diversity in Chemical Structures and Biological Properties of Plant Alkaloids Bhambhani S, Kondhare KR, Giri AP Molecules 03-Jun-2021
PMCID:PMC8199754
doi:10.3390/molecules26113374
PMID:34204857
Taxonomical Study of Noteworthy Species of Botryosphaeria in Japan Hattori Y, Ando Y, Sasaki A, Uechi N, Nakashima C Mycobiology 23-Mar-2021
PMCID:PMC10635109
doi:10.1080/12298093.2021.1895486
PMID:37970183
Chemical Elicitors Induce Rare Bioactive Secondary Metabolites in Deep-Sea Bacteria under Laboratory Conditions de Felício R, Ballone P, Bazzano CF, Alves LF, Sigrist R, Infante GP, Niero H, Rodrigues-Costa F, Fernandes AZ, Tonon LA, Paradela LS, Costa RK, Dias SM, Dessen A, Telles GP, da Silva MA, Lima AO, Trivella DB Metabolites 12-Feb-2021
PMCID:PMC7918856
doi:10.3390/metabo11020107
PMID:33673148

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Daphniphylline-type alkaloids
1-(1,4-Dimethyl-2,8-dioxabicyclo[3.2.1]octan-4-yl)-3-(11-hydroxy-1-methyl-14-propan-2-yl-12-azapentacyclo[8.6.0.02,13.03,7.07,12]hexadecan-2-yl)propan-1-one 163088994 Click to see 485.70 unknown https://doi.org/10.1016/S0040-4039(01)89605-2
1-[(1S,4R,5R)-1,4-dimethyl-2,8-dioxabicyclo[3.2.1]octan-4-yl]-3-[(1R,2S,3R,7S,10R,11R,13R,14S)-11-hydroxy-1-methyl-14-propan-2-yl-12-azapentacyclo[8.6.0.02,13.03,7.07,12]hexadecan-2-yl]propan-1-one 163088995 Click to see 485.70 unknown https://doi.org/10.1016/S0040-4039(01)89605-2
Methyl 3-(1-methyl-14-propan-2-yl-12-azapentacyclo[8.6.0.02,13.03,7.07,11]hexadecan-2-yl)propanoate 14702055 Click to see CC(C)C1CCC2(C3CCC45C3NC1C2(C4CCC5)CCC(=O)OC)C 359.50 unknown https://doi.org/10.1016/0040-4020(72)88030-X
methyl 3-[(1R,2S,3S,7S,10R,11S,13R,14S)-1-methyl-14-propan-2-yl-12-azapentacyclo[8.6.0.02,13.03,7.07,11]hexadecan-2-yl]propanoate 163086719 Click to see CC(C)C1CCC2(C3CCC45C3NC1C2(C4CCC5)CCC(=O)OC)C 359.50 unknown https://doi.org/10.1016/0040-4020(72)88030-X
> Hydrocarbons / Unsaturated hydrocarbons / Olefins / Cyclic olefins / Azulenes
methyl (1S,2R,6S,15S,16R)-1,18-dihydroxy-11-(2-hydroxyethyl)-2,15-dimethyl-9-oxo-4-azapentacyclo[11.4.1.04,16.06,15.010,14]octadeca-10(14),11,13(18)-triene-12-carboxylate 54724259 Click to see CC1CN2CC3CCC(=O)C4=C5C3(C2CC1(C(=C5C(=C4CCO)C(=O)OC)O)O)C 415.50 unknown https://doi.org/10.1002/CHEM.200600056
> Lipids and lipid-like molecules / Fatty Acyls / Eicosanoids / Prostaglandins and related compounds
Daphmacromine A 70686504 Click to see 431.60 unknown https://doi.org/10.1021/NP200960Z
Daphmacromine B 70682263 Click to see CCC1(CCC2(CO1)C3CCC4=C5C2(CC(C5CC4=O)C(=O)OCC)CN(C3)C)OC 431.60 unknown https://doi.org/10.1021/NP200960Z
Daphmacromine C 70684347 Click to see 431.60 unknown https://doi.org/10.1021/NP200960Z
Daphmacromine D 70696900 Click to see 431.60 unknown https://doi.org/10.1021/NP200960Z
Daphmacromine E 70692816 Click to see CCC1(CCC2(CO1)C3CCC4=C5C2(CC(C5CC4=O)C(=O)OC)CN(C3)C)OC 417.50 unknown https://doi.org/10.1021/NP200960Z
Daphmacromine F 70690669 Click to see 417.50 unknown https://doi.org/10.1021/NP200960Z
Daphmacromine G 70686505 Click to see 417.50 unknown https://doi.org/10.1021/NP200960Z
Daphmacromine H 70682264 Click to see CC(C)C1(CCC2(CO1)C3CCC4=C5C2(CC(C5CC4=O)C(=O)OC)CN(C3)C)O 417.50 unknown https://doi.org/10.1021/NP200960Z
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
[(1S,2S,5S,7R,8S)-7-hydroxy-1,5-dimethyl-8-[2-[(1S,2R,3S,7R,10S,13S,14R)-1-methyl-14-propan-2-yl-12-azapentacyclo[8.6.0.02,13.03,7.07,12]hexadecan-2-yl]ethyl]-6-oxabicyclo[3.2.1]octan-2-yl] acetate 163051524 Click to see CC(C)C1CCC2(C3CCC45CCCC4C2(C1N5C3)CCC6C7(CCC(C6(C(O7)O)C)OC(=O)C)C)C 513.80 unknown https://doi.org/10.1016/S0040-4020(01)93819-0
Daphmacromine J 70690670 Click to see CC(C)C1=CCC2(CO1)C3CCC4=C5C2(CC(C5CC4=O)C(=O)OC)CN(C3)C 399.50 unknown https://doi.org/10.1021/NP200960Z
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
Daphylloside 21602024 Click to see 446.40 unknown https://doi.org/10.1248/YAKUSHI1947.86.10_943
methyl (1S,4aS,5R,7aS)-7-(acetyloxymethyl)-5-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate 102285671 Click to see CC(=O)OCC1=CC(C2C1C(OC=C2C(=O)OC)OC3C(C(C(C(O3)CO)O)O)O)O 446.40 unknown https://doi.org/10.1016/S0040-4020(01)93819-0
Methyl 7-(acetyloxymethyl)-5-hydroxy-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate 12309039 Click to see 446.40 unknown https://doi.org/10.1248/YAKUSHI1947.86.10_943
> Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Amino acids and derivatives / Delta amino acids and derivatives
methyl (1R,2R,5S,8S,14R,15R)-2-(acetyloxymethyl)-5-ethyl-6-azapentacyclo[9.5.1.01,5.02,8.014,17]heptadec-11(17)-ene-15-carboxylate 101456792 Click to see 387.50 unknown https://doi.org/10.1002/HLCA.200790222
methyl (1R,2R,5S,8S,14R,15R)-5-ethyl-2-(hydroxymethyl)-6-azapentacyclo[9.5.1.01,5.02,8.014,17]heptadec-11(17)-ene-15-carboxylate 102146075 Click to see 345.50 unknown https://doi.org/10.1002/HLCA.200790222
Methyl 5-ethyl-2-(hydroxymethyl)-6-azapentacyclo[9.5.1.01,5.02,8.014,17]heptadec-11(17)-ene-15-carboxylate 162880181 Click to see 345.50 unknown https://doi.org/10.1002/HLCA.200790222
> Organoheterocyclic compounds / Azaspirodecane derivatives
(1R,6R,9S,10R,13R,16R,17S,23S)-10-hydroxy-17-methyl-11-oxa-19-azahexacyclo[14.6.1.01,13.02,6.09,13.019,23]tricos-2-en-20-one 162870627 Click to see 357.50 unknown https://doi.org/10.1021/NP0700220
Daphhimalenine B 44557841 Click to see 383.50 unknown https://doi.org/10.1021/NP200960Z
Daphmacromine I 70692817 Click to see 385.50 unknown https://doi.org/10.1021/NP200960Z
Daphnezomine K 21589089 Click to see 403.50 unknown https://doi.org/10.1021/NP200960Z
Deoxyyuzurimine 70682265 Click to see 471.60 unknown https://doi.org/10.1021/NP200960Z
Macrodaphnidin 21589083 Click to see 487.60 unknown https://doi.org/10.1021/NP200960Z
methyl (1R,2'S,5S,11R,12R,15R)-2'-ethyl-2'-methoxy-3-methylspiro[3-azatetracyclo[6.5.1.11,5.011,14]pentadec-8(14)-ene-15,5'-oxane]-12-carboxylate 162946387 Click to see 403.60 unknown https://doi.org/10.1246/BCSJ.50.1836
methyl (1R,2R,5S,8S,14R,15R)-5-ethyl-6-hydroxy-2-(hydroxymethyl)-6-azapentacyclo[9.5.1.01,5.02,8.014,17]heptadec-11(17)-ene-15-carboxylate 101456791 Click to see CCC12CCC3(C14CC(C5C4=C(CCC3CN2O)CC5)C(=O)OC)CO 361.50 unknown https://doi.org/10.1002/HLCA.200790222
methyl (1R,3R,4R,10S,14R,15S,18S,19S)-15,19-dihydroxy-18-(hydroxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icosa-7(20),16-diene-3-carboxylate 163043603 Click to see CC1CN2CC3CCC4=C5C(CC4)C(CC56C3(C=CC1(C62O)O)CO)C(=O)OC 401.50 unknown https://doi.org/10.1021/NP070226G
methyl (1R,3R,4R,10S,14R,15S,19S)-15,19-dihydroxy-18-(hydroxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icosa-7(20),16-diene-3-carboxylate 163190590 Click to see 401.50 unknown https://doi.org/10.1021/NP070226G
methyl (1R,3R,4R,10S,14R,16Z,18R)-18-(hydroxymethyl)-14-methyl-15,19-dioxo-12-azapentacyclo[10.6.1.11,4.010,18.07,20]icosa-7(20),16-diene-3-carboxylate 73356413 Click to see CC1CN2CC3CCC4=C5C(CC4)C(CC5(C2=O)C3(C=CC1=O)CO)C(=O)OC 399.50 unknown https://doi.org/10.1021/NP200960Z
methyl (1R,3R,4R,10S,14R,18R)-18-(hydroxymethyl)-14-methyl-15,19-dioxo-12-azapentacyclo[10.6.1.11,4.010,18.07,20]icosa-7(20),16-diene-3-carboxylate 163021630 Click to see CC1CN2CC3CCC4=C5C(CC4)C(CC5(C2=O)C3(C=CC1=O)CO)C(=O)OC 399.50 unknown https://doi.org/10.1021/NP200960Z
methyl (1R,3R,4R,10S,14S,15R,18S,19R)-19-hydroxy-18-(hydroxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icosa-7(20),16-diene-3-carboxylate 162979606 Click to see 385.50 unknown https://doi.org/10.1021/NP070226G
methyl (1R,3R,4R,10S,14S,19R)-19-hydroxy-18-(hydroxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icosa-7(20),16-diene-3-carboxylate 163186819 Click to see 385.50 unknown https://doi.org/10.1021/NP070226G
methyl (1R,3R,4S,10S,14R,15R,18R,19S)-18-(hydroxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate 162947907 Click to see 371.50 unknown https://doi.org/10.1016/S0040-4020(01)93819-0
methyl (1R,3R,4S,10S,14S,15R,17S,18S,19R)-17,19-dihydroxy-14,18-dimethyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate 162860560 Click to see 387.50 unknown https://doi.org/10.1016/S0040-4020(01)93819-0
methyl (1R,3R,4S,10S,14S,15R,18R,19S)-18-(acetyloxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate 162932131 Click to see 413.50 unknown https://doi.org/10.1016/S0040-4020(01)93819-0
methyl (1R,3S,4R,10S,14S,15R,17R,18S,19R)-17,19-dihydroxy-14,18-dimethyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate 163188653 Click to see CC1CN2CC3CCC4=C5C(CC4)C(CC56C3(C(CC1C62O)O)C)C(=O)OC 387.50 unknown https://doi.org/10.1016/S0040-4039(01)89605-2
methyl (1R,3S,4R,10S,14S,15R,18R,19S)-18-(acetyloxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate 162932130 Click to see 413.50 unknown https://doi.org/10.1016/S0040-4039(01)89605-2
methyl (1S,3S,4R,10R,14R,15S,17S,18R,19S)-17-acetyloxy-18-(acetyloxymethyl)-19-hydroxy-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate 162916071 Click to see 487.60 unknown https://doi.org/10.1016/S0040-4039(01)89605-2
Methyl 15,19-dihydroxy-18-(hydroxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icosa-7(20),16-diene-3-carboxylate 73323610 Click to see CC1CN2CC3CCC4=C5C(CC4)C(CC56C3(C=CC1(C62O)O)CO)C(=O)OC 401.50 unknown https://doi.org/10.1021/NP070226G
Methyl 17,19-dihydroxy-14,18-dimethyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate 12312637 Click to see 387.50 unknown https://doi.org/10.1016/S0040-4039(01)89605-2
Methyl 18-(acetyloxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate 12312639 Click to see 413.50 unknown https://doi.org/10.1016/S0040-4039(01)89605-2
Methyl 19-hydroxy-18-(hydroxymethyl)-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icosa-7(20),16-diene-3-carboxylate 74075817 Click to see 385.50 unknown https://doi.org/10.1021/NP070226G
Methyl 2'-ethyl-2'-methoxy-3-methylspiro[3-azatetracyclo[6.5.1.11,5.011,14]pentadec-8(14)-ene-15,5'-oxane]-12-carboxylate 162946384 Click to see 403.60 unknown https://doi.org/10.1246/BCSJ.50.1836
pordamacrine A 44444998 Click to see CC1CN2CC3CCC4=C5C(CC4)C(CC56C3(C=CC1(C62O)O)CO)C(=O)OC 401.50 unknown https://doi.org/10.1021/NP070226G
Pordamacrine B 44444999 Click to see 385.50 unknown https://doi.org/10.1021/NP070226G
Yuzurimine 431853 Click to see 487.60 unknown https://doi.org/10.1016/S0040-4039(01)89605-2
https://doi.org/10.1021/NP200960Z
Yuzurimine C 70688608 Click to see 399.50 unknown https://doi.org/10.1021/NP200960Z
> Organoheterocyclic compounds / Indoles and derivatives
daphnimacropodine B 23625868 Click to see 389.50 unknown https://doi.org/10.1021/NP0700220
Daphnimacropodine C 23625869 Click to see 371.50 unknown https://doi.org/10.1021/NP0700220
Daphtenidine C 11576707 Click to see 485.60 unknown https://doi.org/10.1021/NP200960Z
> Organoheterocyclic compounds / Indolizidines
(1R,7R,10R,11S,15S,18S,23S)-11-methyl-5-oxa-13-azahexacyclo[11.9.1.01,7.07,15.010,23.018,22]tricos-21-en-4-one 163009003 Click to see 341.50 unknown https://doi.org/10.1016/S0040-4020(01)93819-0
(1R,7R,10S,11R,15S,18R,23R)-10-hydroxy-11-methyl-5-oxa-13-azahexacyclo[11.9.1.01,7.07,15.010,23.018,22]tricos-21-en-4-one 162995862 Click to see 357.50 unknown https://doi.org/10.1021/NP0700220
10-Hydroxy-11-methyl-5-oxa-13-azahexacyclo[11.9.1.01,7.07,15.010,23.018,22]tricos-21-en-4-one 162995861 Click to see 357.50 unknown https://doi.org/10.1021/NP0700220
Macropodumine A 11689290 Click to see 373.40 unknown https://doi.org/10.1002/CHEM.200600056
methyl 3-[(2S,3R,8R,11S,12R,15R,16S)-12-(hydroxymethyl)-16-methyl-1-azapentacyclo[9.6.1.02,15.03,12.04,8]octadec-4-en-3-yl]propanoate 23625870 Click to see 373.50 unknown https://doi.org/10.1021/NP0700220

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