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Haplophyllum bucharicum

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Table of Contents

Details
Description
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Biological Material
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Details Top

Internal ID UUID64401fb5a3d64443681612
Scientific name Haplophyllum bucharicum
Authority Litv.
First published in Trudy Bot. Muz. Imp. Akad. Nauk 7: 73 (1910)

Description Top

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Synonyms Top

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Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000715490
Tropicos 28101470
KEW urn:lsid:ipni.org:names:773859-1
Open Tree Of Life 1046433
Observations.org 118376
NCBI Taxonomy 1006069
IPNI 773859-1
GBIF 5593240
Elurikkus 613083

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Furoquinoline Alkaloids: Insights into Chemistry, Occurrence, and Biological Properties Szewczyk A, Pęczek F Int J Mol Sci 15-Aug-2023
PMCID:PMC10454094
doi:10.3390/ijms241612811
PMID:37628986
Chemistry and Biological Activities of Naturally Occurring and Structurally Modified Podophyllotoxins Jin L, Song Z, Cai F, Ruan L, Jiang R Molecules 30-Dec-2022
PMCID:PMC9822336
doi:10.3390/molecules28010302
PMID:36615496
Diphyllin Shows a Broad-Spectrum Antiviral Activity against Multiple Medically Important Enveloped RNA and DNA Viruses Štefánik M, Bhosale DS, Haviernik J, Straková P, Fojtíková M, Dufková L, Huvarová I, Salát J, Bartáček J, Svoboda J, Sedlák M, Růžek D, Miller AD, Eyer L Viruses 09-Feb-2022
PMCID:PMC8874615
doi:10.3390/v14020354
PMID:35215947
Progress of Plant Medicine Derived Extracts and Alkaloids on Modulating Viral Infections and Inflammation Ti H, Zhuang Z, Yu Q, Wang S Drug Des Devel Ther 31-Mar-2021
PMCID:PMC8020337
doi:10.2147/DDDT.S299120
PMID:33833499
A Molecular Modeling Approach to Identify Potential Antileishmanial Compounds Against the Cell Division Cycle (cdc)-2-Related Kinase 12 (CRK12) Receptor of Leishmania donovani Broni E, Kwofie SK, Asiedu SO, Miller WA III, Wilson MD Biomolecules 18-Mar-2021
PMCID:PMC8003136
doi:10.3390/biom11030458
PMID:33803906
Antiviral Activity of Vacuolar ATPase Blocker Diphyllin against SARS-CoV-2 Stefanik M, Strakova P, Haviernik J, Miller AD, Ruzek D, Eyer L Microorganisms 25-Feb-2021
PMCID:PMC7996309
doi:10.3390/microorganisms9030471
PMID:33668694
Use of Natural Products in Leishmaniasis Chemotherapy: An Overview Gervazoni LF, Barcellos GB, Ferreira-Paes T, Almeida-Amaral EE Front Chem 23-Nov-2020
PMCID:PMC7732490
doi:10.3389/fchem.2020.579891
PMID:33330368
Therapeutic Interventions for Countering Leishmaniasis and Chagas’s Disease: From Traditional Sources to Nanotechnological Systems Souto EB, Dias-Ferreira J, Craveiro SA, Severino P, Sanchez-Lopez E, Garcia ML, Silva AM, Souto SB, Mahant S Pathogens 01-Aug-2019
PMCID:PMC6789685
doi:10.3390/pathogens8030119
PMID:31374930
Emerging therapeutic targets for treatment of leishmaniasis Sundar S, Singh B Expert Opin Ther Targets 09-May-2018
PMCID:PMC6047532
doi:10.1080/14728222.2018.1472241
PMID:29718739
The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases Cheuka PM, Mayoka G, Mutai P, Chibale K Molecules 31-Dec-2016
PMCID:PMC6155950
doi:10.3390/molecules22010058
PMID:28042865
Sub-chronic toxicological evaluation of cleistanthin A and cleistanthin B from the leaves of Cleistanthus collinus (Roxb.) Parasuraman S, Raveendran R, Rajesh NG, Nandhakumar S Toxicol Rep 19-Aug-2014
PMCID:PMC5598356
doi:10.1016/j.toxrep.2014.08.006
PMID:28962273
Diuretic Effects of Cleistanthin A and Cleistanthin B from the Leaves of Cleistanthus Collinus in Wistar Rats Parasuraman S, Raveendran R J Young Pharm 01-Apr-2012
PMCID:PMC3385220
doi:10.4103/0975-1483.96616
PMID:22754257
The conformational mobility of the dihydropyran ring of the alkaloid folifine M. R. Yagudaev, S. Yu. Yunusov Springer Science and Business Media LLC 09-Jul-2008
doi:10.1007/BF00565219
Components ofHaplophyllum bucharicum I. A. Bessonova Springer Science and Business Media LLC 14-Nov-2005
doi:10.1007/BF02238348
Buchapine — A new alkaloid fromHaplophyllum bucharicum E. F. Nesmelova, I. A. Bessonova, S. Yu. Yunusov Springer Science and Business Media LLC 22-Nov-2004
doi:10.1007/BF00579671

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lignans, neolignans and related compounds / Arylnaphthalene lignans
Acetyldiphyllin 1760987 Click to see CC(=O)OC1=C2COC(=O)C2=C(C3=CC(=C(C=C31)OC)OC)C4=CC5=C(C=C4)OCO5 422.40 unknown https://doi.org/10.1007/BF02238348
Diphyllin 100492 Click to see COC1=C(C=C2C(=C1)C(=C3C(=C2O)COC3=O)C4=CC5=C(C=C4)OCO5)OC 380.30 unknown https://doi.org/10.1007/BF02238348
Justicidin B 442882 Click to see COC1=CC2=CC3=C(C(=C2C=C1OC)C4=CC5=C(C=C4)OCO5)C(=O)OC3 364.30 unknown https://doi.org/10.1007/BF02238348
Retrochinensin 122805 Click to see COC1=C(C=C(C=C1)C2=C3C=C4C(=CC3=CC5=C2COC5=O)OCO4)OC 364.30 unknown https://doi.org/10.1007/BF02238348
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols
1-Triacontanol 68972 Click to see CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO 438.80 unknown https://doi.org/10.1007/BF02238348
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Cholestane steroids / Cholesterols and derivatives
Cholesterol 5997 Click to see CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C 386.70 unknown https://doi.org/10.1007/BF02238348
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Ergostane steroids / Ergosterols and derivatives
(3S,8S,9S,14S,17R)-17-[(2R,5R)-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 134766514 Click to see CC(C)C(C)CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C 400.70 unknown https://doi.org/10.1007/BF02238348
5-Cholestene-3-ol, 24-methyl- 312822 Click to see CC(C)C(C)CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C 400.70 unknown https://doi.org/10.1007/BF02238348
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1007/BF02238348
https://doi.org/10.1007/BF00579670
24-Ethylcholest-5-en-3beta-ol 22012 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1007/BF02238348
Beta-Sitosterol 222284 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1007/BF00579670
Stigmasterol 5280794 Click to see CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 412.70 unknown https://doi.org/10.1007/BF02238348
> Organoheterocyclic compounds / Quinolines and derivatives / Dihydrofuranoquinolines
(2S,3R)-2,3-dimethyl-3-[2-[(4R)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]ethyl]-2,9-dihydrofuro[2,3-b]quinolin-4-one 163029830 Click to see CC1C(C2=C(O1)NC3=CC=CC=C3C2=O)(C)CCC4C(OC(O4)(C)C)(C)C 371.50 unknown https://doi.org/10.1007/BF00563744
2,3-Dimethyl-3-[2-(2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)ethyl]-2,9-dihydrofuro[2,3-b]quinolin-4-one 21769915 Click to see CC1C(C2=C(O1)NC3=CC=CC=C3C2=O)(C)CCC4C(OC(O4)(C)C)(C)C 371.50 unknown https://doi.org/10.1007/BF00563744
> Organoheterocyclic compounds / Quinolines and derivatives / Furanoquinolines
4,8-dimethoxy-9H-furo[2,3-b]quinolin-7-one 165368 Click to see COC1=C2C=CC(=O)C(=C2NC3=C1C=CO3)OC 245.23 unknown https://doi.org/10.1007/BF02238348
Dictamnine 68085 Click to see COC1=C2C=COC2=NC3=CC=CC=C31 199.20 unknown https://doi.org/10.1007/BF02238348
gamma-Fagarine 107936 Click to see COC1=CC=CC2=C1N=C3C(=C2OC)C=CO3 229.23 unknown https://doi.org/10.1007/BF02238348
Haplopine 5281846 Click to see COC1=C2C=COC2=NC3=C1C=CC(=C3OC)O 245.23 unknown https://doi.org/10.1007/BF02238348
Robustine 164950 Click to see COC1=C2C=COC2=NC3=C1C=CC=C3O 215.20 unknown https://doi.org/10.1007/BF02238348
Skimmianine 6760 Click to see COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC 259.26 unknown https://doi.org/10.1007/BF02238348
https://doi.org/10.1007/BF00568498
https://doi.org/10.1007/BF00579670
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Hydroquinolones
4-[(6S)-6,7-dihydroxy-3,7-dimethyloct-2-enoxy]-1H-quinolin-2-one 6992054 Click to see CC(=CCOC1=CC(=O)NC2=CC=CC=C21)CCC(C(C)(C)O)O 331.40 unknown https://doi.org/10.1007/BF00579670
4-[(E,6S)-6,7-dihydroxy-3,7-dimethyloct-2-enoxy]-1H-quinolin-2-one 1549048 Click to see CC(=CCOC1=CC(=O)NC2=CC=CC=C21)CCC(C(C)(C)O)O 331.40 unknown https://doi.org/10.1007/BF00579670
4-Methoxy-1H-quinolin-2-one 600167 Click to see COC1=CC(=O)NC2=CC=CC=C21 175.18 unknown https://doi.org/10.1007/BF02238348
Buchapine 461150 Click to see CC(=CCC1(C(=O)C2=CC=CC=C2NC1=O)C(C)(C)C=C)C 297.40 unknown https://doi.org/10.1007/BF02238348
https://doi.org/10.1007/BF00579671
Bucharaine 5338262 Click to see CC(=CCOC1=CC(=O)NC2=CC=CC=C21)CCC(C(C)(C)O)O 331.40 unknown https://doi.org/10.1007/BF02238348
https://doi.org/10.1007/BF00568498
Bucharidine 54680116 Click to see CC(C1=C(C2=CC=CC=C2NC1=O)O)C3(CCC(C(O3)(C)C)O)C 331.40 unknown https://doi.org/10.1007/BF00568498
Pteleprenine 167633 Click to see CC(=CCC1=C(C2=C(C3=C(C=C2)OCO3)N(C1=O)C)OC)C 301.34 unknown https://doi.org/10.1007/BF00579671
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Hydroxyquinolones
2,4-Quinolinediol 54680871 Click to see C1=CC=C2C(=C1)C(=CC(=O)N2)O 161.16 unknown https://doi.org/10.1007/BF02238348
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Pyranoquinolines
9-methoxy-2,2-dimethyl-6H-pyrano[3,2-c]quinolin-5-one 648601 Click to see CC1(C=CC2=C(O1)C3=C(C=CC(=C3)OC)NC2=O)C 257.28 unknown https://doi.org/10.1007/BF02238348
Flindersine 68230 Click to see CC1(C=CC2=C(O1)C3=CC=CC=C3NC2=O)C 227.26 unknown https://doi.org/10.1007/BF00568498
https://doi.org/10.1007/BF02238348
Ribalinine 932818 Click to see CC1(C(CC2=C(O1)N(C3=CC=CC=C3C2=O)C)O)C 259.30 unknown https://doi.org/10.1007/BF00565219

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