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Internal ID UUID644006f32d396933929674
Scientific name Aconitum bulleyanum
Authority Diels
First published in Notes Roy. Bot. Gard. Edinburgh 5: 267 (1912)

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Language Common/alternative name
Chinese 小黑牛
Chinese 滇西乌头

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000517015
Tropicos 27102949
KEW urn:lsid:ipni.org:names:707226-1
The Plant List kew-2618473
Open Tree Of Life 384359
NCBI Taxonomy 226111
IPNI 707226-1
GBIF 3926740

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
The known, unknown, and the intriguing about members of a critically endangered traditional medicinal plant genus Aconitum Kakkar RA, Haneen MA, Parida AC, Sharma G Front Plant Sci 28-Jul-2023
PMCID:PMC10421671
doi:10.3389/fpls.2023.1139215
PMID:37575934
Plant-derived natural products targeting ion channels for pain Goyal S, Goyal S, Goins AE, Alles SR Neurobiol Pain 17-Apr-2023
PMCID:PMC10160805
doi:10.1016/j.ynpai.2023.100128
PMID:37151956
Bulleyaconitine A reduces fracture-induced pain and promotes fracture healing in mice Peng J, Xiao S, Xie J, Fu W Front Pharmacol 23-Jan-2023
PMCID:PMC9899823
doi:10.3389/fphar.2023.1046514
PMID:36755956
Plant and fungi derived analgesic natural products targeting voltage-gated sodium and calcium channels Calderon-Rivera A, Loya-Lopez S, Gomez K, Khanna R Channels (Austin) 26-Aug-2022
PMCID:PMC9423853
doi:10.1080/19336950.2022.2103234
PMID:36017978
Structural Advances in Voltage-Gated Sodium Channels Jiang D, Zhang J, Xia Z Front Pharmacol 03-Jun-2022
PMCID:PMC9204039
doi:10.3389/fphar.2022.908867
PMID:35721169
Structural basis for modulation of human NaV1.3 by clinical drug and selective antagonist Li X, Xu F, Xu H, Zhang S, Gao Y, Zhang H, Dong Y, Zheng Y, Yang B, Sun J, Zhang XC, Zhao Y, Jiang D Nat Commun 11-Mar-2022
PMCID:PMC8917200
doi:10.1038/s41467-022-28808-5
PMID:35277491
Classification, Toxicity and Bioactivity of Natural Diterpenoid Alkaloids Thawabteh AM, Thawabteh A, Lelario F, Bufo SA, Scrano L Molecules 05-Jul-2021
PMCID:PMC8271992
doi:10.3390/molecules26134103
PMID:34279443
Bulleyaconitine A Inhibits Morphine-Induced Withdrawal Symptoms, Conditioned Place Preference, and Locomotor Sensitization Via Microglial Dynorphin A Expression Zhao MJ, Wang MY, Ma L, Ahmad KA, Wang YX Front Pharmacol 26-Feb-2021
PMCID:PMC7953057
doi:10.3389/fphar.2021.620926
PMID:33716748
Effects of alkaloids on peripheral neuropathic pain: a review Zhu C, Liu N, Tian M, Ma L, Yang J, Lan X, Ma H, Niu J, Yu J Chin Med 02-Oct-2020
PMCID:PMC7532100
doi:10.1186/s13020-020-00387-x
PMID:33024448
Synthesis and Evaluation of a Series of New Bulleyaconitine A Derivatives as Analgesics Zhang X, Shang YS, Gao F, Fang DM, Li XH, Zhou XL ACS Omega 17-Aug-2020
PMCID:PMC7450621
doi:10.1021/acsomega.0c02944
PMID:32875257
Bulleyaconitine A Inhibits Visceral Nociception and Spinal Synaptic Plasticity through Stimulation of Microglial Release of Dynorphin A Huang SN, Wei J, Huang LT, Ju PJ, Chen J, Wang YX Neural Plast 23-May-2020
PMCID:PMC7262664
doi:10.1155/2020/1484087
PMID:32565774
Oral application of bulleyaconitine A attenuates morphine tolerance in neuropathic rats by inhibiting long-term potentiation at C-fiber synapses and protein kinase C gamma in spinal dorsal horn Mai JZ, Liu C, Huang Z, Mai CL, Zhou X, Zhang J, Liu XG Mol Pain 14-Apr-2020
PMCID:PMC7160774
doi:10.1177/1744806920917242
PMID:32290780
Bulleyaconitine A Effectively Relieves Allergic Lung Inflammation in a Murine Asthmatic Model Zhan X, Zhang W, Sun T, Feng Y, Xi Y, Jiang Y, Tang X Med Sci Monit 04-Mar-2019
PMCID:PMC6413559
doi:10.12659/MSM.915427
PMID:30828084
Mechanisms for therapeutic effect of bulleyaconitine A on chronic pain Xie MX, Zhu HQ, Pang RP, Wen BT, Liu XG Mol Pain 05-Sep-2018
PMCID:PMC6125851
doi:10.1177/1744806918797243
PMID:30180777
Bulleyaconitine A attenuates hyperexcitability of dorsal root ganglion neurons induced by spared nerve injury: The role of preferably blocking Nav1.7 and Nav1.3 channels Xie MX, Yang J, Pang RP, Zeng WA, Ouyang HD, Liu YQ, Liu XG Mol Pain 22-May-2018
PMCID:PMC5967161
doi:10.1177/1744806918778491
PMID:29783906

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Aconitane-type diterpenoid alkaloids
[(2R,3R,5S,6S,8R,13R,17S)-8-acetyloxy-11-ethyl-5,14-dihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] 4-methoxybenzoate 5315414 Click to see CCN1CC2(C(CC(C34C2C(C(C31)C5(CC(C6(CC4C5C6OC(=O)C7=CC=C(C=C7)OC)O)OC)OC(=O)C)OC)OC)O)COC 659.80 unknown https://doi.org/10.1016/J.JCHROMB.2013.10.020
Foresaconitine 13817036 Click to see CCN1CC2(CCC(C34C2C(C(C31)C5(CC(C6CC4C5C6OC(=O)C7=CC=C(C=C7)OC)OC)OC(=O)C)OC)OC)COC 627.80 unknown https://doi.org/10.1016/J.JPBA.2007.04.016

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