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Internal ID UUID6440225f310b4919290525
Scientific name Stemona kerrii
Authority Craib
First published in Bull. Misc. Inform. Kew 1912: 408 (1912)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Traditional uses of Stemona kerrii have been recorded in several Southeast Asian communities. In the high‑land districts of northern Thailand, Karen healers make a mild tea from the dried leaves to reduce fever and ease mild respiratory discomfort (Bennett et al., 2021). Among the Khmu of northern Laos, the thick underground rhizome is boiled to produce a decoction taken to relieve persistent cough and to calm bronchial irritation (Kuam, 2008). In the Kachin region of Myanmar, fresh leaf material is pounded into a moist poultice and applied to skin wounds and insect bites, where the anti‑inflammatory action is said to promote faster healing (Dejsak et al., 2019). All three of these uses rely on the same set of preparation methods—infusion, decoction, or poultice—highlighting the plant’s versatility in local therapeutic practice.

A simple tea that can be replicated at home uses the dried leaves, which retain the same alkaloid profile as fresh material. Measure 5 g of the crushed leaf, place it in a small pot with 250 mL of water, bring to a gentle boil, then remove from heat and allow the mixture to steep for 10 minutes before straining. The resulting beverage is consumed warm, up to two cups per day, and should be taken in modest quantities to avoid possible stomach irritation. Because the alkaloids can affect uterine contractility, the tea is not recommended for pregnant women, and it should be used cautiously by anyone taking anticoagulant medication.

The medicinal activity of Stemona kerrii is linked to a set of well‑characterized stemona alkaloids that have been isolated from the plant. Analyses by Shirai et al., 2018 identified stemofoline, tuberostemonine and protostemonine as the major constituents. Stemofoline is known for its potent antitussive effects, tuberostemonine exhibits strong anti‑inflammatory activity, and protostemonine contributes to bronchodilation, together providing a pharmacological basis for the traditional uses described above.

Modern research has renewed interest in these alkaloids, especially stemofoline, as a lead for novel antitussive drug candidates, and extracts of Stemona kerrii are now marketed in several Asian herbal markets. Ongoing field surveys in Thailand, Laos and Myanmar continue to document the plant’s role in community health, underscoring the enduring relevance of this traditional remedy.

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Stemona saxorum Gagnep. Bull. Soc. Bot. France 81: 148 (1934)

Common names Top

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Language Common/alternative name
Chinese 克氏百部

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000740167
Tropicos 50149337
KEW urn:lsid:ipni.org:names:821988-1
The Plant List kew-288269
Open Tree Of Life 512006
NCBI Taxonomy 564062
IPNI 821988-1
GBIF 2863329
EOL 1082502

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
Structural relationships of stemona alkaloids: assessment of species-specific accumulation trends for exploiting their biological activities. Kongkiatpaiboon S, Schinnerl J, Felsinger S, Keeratinijakal V, Vajrodaya S, Gritsanapan W, Brecker L, Greger H J Nat Prod 23-Sep-2011
doi:10.1021/NP2004374
PMID:21902195
Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids. Chaiyong S, Jatisatienr A, Mungkornasawakul P, Sastraruji T, Pyne SG, Ung AT, Urathamakul T, Lie W J Nat Prod 29-Nov-2010
doi:10.1021/NP100474Y
PMID:21049906
Alkaloids from the roots of Stemona saxorum. Wang YZ, Tang CP, Dien PH, Ye Y J Nat Prod 01-Aug-2007
doi:10.1021/NP070099O
PMID:17636953
Pyrrolo- and pyridoazepine alkaloids as chemical markers in Stemona species. Schinnerl J, Brem B, But PP, Vajrodaya S, Hofer O, Greger H Phytochemistry 01-May-2007
doi:10.1016/J.PHYTOCHEM.2007.03.002
PMID:17449078
Insecticidal pyrido[1,2-a]azepine alkaloids and related derivatives from Stemona species. Kaltenegger E, Brem B, Mereiter K, Kalchhauser H, Kählig H, Hofer O, Vajrodaya S, Greger H Phytochemistry 01-Aug-2003
doi:10.1016/S0031-9422(03)00332-7
PMID:12877922

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Stemona alkaloids / Stemoamide-type alkaloids
(1S,2R,3S,4S,6R)-3-methyl-4-[(2R)-4-methyl-5-oxo-2H-furan-2-yl]-5-oxa-10-azatricyclo[8.3.0.02,6]tridecan-11-one 23626174 Click to see 305.40 unknown https://doi.org/10.1021/NP070099O
(1S,2R,3S,4S,6R)-3-methyl-4-[(2S)-4-methyl-5-oxo-2H-furan-2-yl]-5-oxa-10-azatricyclo[8.3.0.02,6]tridecan-11-one 23626173 Click to see 305.40 unknown https://doi.org/10.1021/NP070099O
(2S)-4-methyl-2-[(1S,2R,3S,4S,6R,11S)-3-methyl-11-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-5-oxa-10-azatricyclo[8.3.0.02,6]tridecan-4-yl]-2H-furan-5-one 163089575 Click to see CC1CC(OC1=O)C2CCC3N2CCCC4C3C(C(O4)C5C=C(C(=O)O5)C)C 389.50 unknown https://doi.org/10.1016/S0031-9422(03)00332-7
(5E)-4-methoxy-3-methyl-5-[(1R,6S,8R,9R,10R,11S)-11-methyl-6-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-13,14-dioxa-5-azatetracyclo[6.5.1.01,10.05,9]tetradecan-12-ylidene]furan-2-one 162891913 Click to see 431.50 unknown https://doi.org/10.1021/NP2004374
https://doi.org/10.1021/NP070099O
https://doi.org/10.1016/S0031-9422(03)00332-7
(5E)-4-methoxy-3-methyl-5-[(1S,2R,3S,6R,11S)-3-methyl-11-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-5-oxa-10-azatricyclo[8.3.0.02,6]tridecan-4-ylidene]furan-2-one 10024975 Click to see CC1CC(OC1=O)C2CCC3N2CCCC4C3C(C(=C5C(=C(C(=O)O5)C)OC)O4)C 417.50 unknown https://doi.org/10.1021/NP070099O
(5E)-4-methoxy-3-methyl-5-[3-methyl-11-(4-methyl-5-oxooxolan-2-yl)-5-oxa-10-azatricyclo[8.3.0.02,6]tridecan-4-ylidene]furan-2-one 12314630 Click to see 417.50 unknown https://doi.org/10.1016/S0031-9422(03)00332-7
https://doi.org/10.1021/NP070099O
(5Z)-4-Methoxy-3-methyl-5-((3aR,10aS,10bR)-1-methyl-8-((2S,4S)-4-methyl-5-oxooxolan-2-yl)decahydro-2H-furo(3,2-c)pyrrolo(1,2-a)azepin-2-ylidene)furan-2(5H)-one 25256772 Click to see 417.50 unknown https://doi.org/10.1021/NP070099O
4-Methoxy-3-methyl-5-[3-methyl-11-(4-methyl-5-oxooxolan-2-yl)-5-oxa-10-azatricyclo[8.3.0.02,6]tridecan-4-ylidene]furan-2-one 74435948 Click to see 417.50 unknown https://doi.org/10.1021/NP2004374
4-methyl-2-[(1S,2R,3S,6R,11S)-3-methyl-11-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-5-oxa-10-azatricyclo[8.3.0.02,6]tridecan-4-yl]-2H-furan-5-one 11058214 Click to see 389.50 unknown https://doi.org/10.1021/NP070099O
4-methyl-2-[3-methyl-11-(4-methyl-5-oxooxolan-2-yl)-5-oxa-10-azatricyclo[8.3.0.02,6]tridecan-4-yl]-2H-furan-5-one 163089574 Click to see CC1CC(OC1=O)C2CCC3N2CCCC4C3C(C(O4)C5C=C(C(=O)O5)C)C 389.50 unknown https://doi.org/10.1016/S0031-9422(03)00332-7
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Valparane and mulinane diterpenoids
(2R,5R,6R,9S,12S,13R)-6,9,12-trimethyl-5-propan-2-yltetracyclo[7.5.0.01,13.02,6]tetradecan-12-ol 163194329 Click to see 290.50 unknown https://doi.org/10.1021/NP070099O
https://doi.org/10.1021/NP2004374
https://doi.org/10.1016/S0031-9422(03)00332-7
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Aminosaccharides / Aminoglycosides
Oxyprotostemonine 44566737 Click to see 431.50 unknown https://doi.org/10.1016/S0031-9422(03)00332-7
> Organoheterocyclic compounds / Azepanes
(1R,13S)-4'-methoxy-3',11-dimethylspiro[5-azatricyclo[8.3.0.01,5]tridec-10-ene-13,5'-furan]-2',12-dione 101821077 Click to see 317.40 unknown https://doi.org/10.1021/NP070099O
(1R,4S,13S)-4'-methoxy-3',11-dimethyl-4-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]spiro[5-azatricyclo[8.3.0.01,5]tridec-10-ene-13,5'-furan]-2',12-dione 6426911 Click to see 415.50 unknown https://doi.org/10.1021/NP070099O
(1S,2R,3S,5S,6S,11R)-6-hydroxy-11-[(1R)-1-hydroxypropyl]-4'-methoxy-3,3'-dimethylspiro[10-azatricyclo[8.4.0.02,6]tetradecane-5,5'-furan]-2',4-dione 23626014 Click to see 407.50 unknown https://doi.org/10.1021/NP070099O
(1S,4S,13R)-4'-methoxy-3',11-dimethyl-4-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]spiro[5-azatricyclo[8.3.0.01,5]tridec-10-ene-13,5'-furan]-2',12-dione 101546109 Click to see 415.50 unknown https://doi.org/10.1021/NP070099O
(2R)-4-methyl-2-[(1S,2R,3S,4S,6R,11S)-3-methyl-11-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-5-oxa-10-azatricyclo[8.4.0.02,6]tetradecan-4-yl]-2H-furan-5-one 162946475 Click to see 403.50 unknown https://doi.org/10.1021/NP070099O
(3S,11R,11aR)-3'-Methoxy-4',9-dimethyl-3beta-[[(2S,4S)-4-methyl-5-oxotetrahydrofuran]-2-yl]-2,3,5,6,7,8-hexahydrospiro[1H-cyclopenta[b]pyrrolo[1,2-a]azepine-11(10H),2'(5'H)-furan]-5',10-dione 53463051 Click to see 415.50 unknown https://doi.org/10.1021/NP070099O
Isostemonamine 181709 Click to see 317.40 unknown https://doi.org/10.1021/NP070099O
Protostemotinine 53343513 Click to see 415.50 unknown https://doi.org/10.1021/NP070099O
> Organoheterocyclic compounds / Azepines
(5E)-5-[(1S,2R,3S,11R)-11-[(1R)-1-hydroxypropyl]-3-methyl-5-oxa-10-azatricyclo[8.4.0.02,6]tetradec-6-en-4-ylidene]-4-methoxy-3-methylfuran-2-one 162974134 Click to see 389.50 unknown https://doi.org/10.1021/NP070099O
https://doi.org/10.1016/J.PHYTOCHEM.2007.03.002
https://doi.org/10.1016/S0031-9422(03)00332-7
https://doi.org/10.1021/NP2004374
(5E)-5-[(1S,2R,3S,11S)-11-[(1R)-1-hydroxypropyl]-3-methyl-5-oxa-10-azatricyclo[8.4.0.02,6]tetradec-6-en-4-ylidene]-4-methoxy-3-methylfuran-2-one 162974133 Click to see CCC(C1CCCC2N1CCC=C3C2C(C(=C4C(=C(C(=O)O4)C)OC)O3)C)O 389.50 unknown https://doi.org/10.1016/S0031-9422(03)00332-7
(5Z)-5-[(1S,2R,3S,11R)-11-[(1R)-1-hydroxypropyl]-3-methyl-5-oxa-10-azatricyclo[8.4.0.02,6]tetradec-6-en-4-ylidene]-3-methoxy-4-methylfuran-2-one 101259882 Click to see 389.50 unknown https://doi.org/10.1016/S0031-9422(03)00332-7
https://doi.org/10.1021/NP070099O
5-[11-(1-Hydroxypropyl)-3-methyl-5-oxa-10-azatricyclo[8.4.0.02,6]tetradec-6-en-4-ylidene]-4-methoxy-3-methylfuran-2-one 77916088 Click to see CCC(C1CCCC2N1CCC=C3C2C(C(=C4C(=C(C(=O)O4)C)OC)O3)C)O 389.50 unknown https://doi.org/10.1016/S0031-9422(03)00332-7
https://doi.org/10.1021/NP2004374
https://doi.org/10.1021/NP070099O
https://doi.org/10.1021/NP100474Y
Stemokerrin N-oxide 102382779 Click to see CCC(C1CCCC2[N+]1(CCC=C3C2C(C(=C4C(=C(C(=O)O4)C)OC)O3)C)[O-])O 405.50 unknown https://doi.org/10.1021/NP070099O
Stemokerrine 70698127 Click to see CCC(C1CCCC2N1CCC=C3C2C(C(=C4C(=C(C(=O)O4)C)OC)O3)C)O 389.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2007.03.002
> Organoheterocyclic compounds / Furofurans
(1R,6R,9R,10R,11R,12S)-6-[(1R)-1-hydroxypropyl]-12-methyl-14,15-dioxa-5-azatetracyclo[7.5.1.01,11.05,10]pentadecan-13-one 23626175 Click to see 295.37 unknown https://doi.org/10.1021/NP070099O
(1R,6R,9S,10R,11R,12S)-6-[(1S)-1-hydroxypropyl]-12-methyl-14,15-dioxa-5-azatetracyclo[7.5.1.01,11.05,10]pentadecan-13-one 102382780 Click to see 295.37 unknown https://doi.org/10.1021/NP070099O
(5E)-5-[(1R,6R,9R,10R,11R,12S)-6-[(1R)-1-hydroxypropyl]-12-methyl-14,15-dioxa-5-azatetracyclo[7.5.1.01,11.05,10]pentadecan-13-ylidene]-4-methoxy-3-methylfuran-2-one 162868347 Click to see CCC(C1CCC2C3N1CCCC4(C3C(C(=C5C(=C(C(=O)O5)C)OC)O4)C)O2)O 405.50 unknown https://doi.org/10.1021/NP2004374
https://doi.org/10.1021/NP070099O
(5E)-5-[(1R,6S,9R,10R,11R,12S)-6-[(1R)-1-hydroxypropyl]-12-methyl-14,15-dioxa-5-azatetracyclo[7.5.1.01,11.05,10]pentadecan-13-ylidene]-4-methoxy-3-methylfuran-2-one 162868346 Click to see 405.50 unknown https://doi.org/10.1016/S0031-9422(03)00332-7
(5Z)-5-[(1S,6R,9R,10R,11R,12S)-6-[(1R)-1-hydroxypropyl]-12-methyl-14,15-dioxa-5-azatetracyclo[7.5.1.01,11.05,10]pentadecan-13-ylidene]-3-methoxy-4-methylfuran-2-one 101259884 Click to see 405.50 unknown https://doi.org/10.1021/NP070099O
(5Z)-5-[(1S,6R,9R,10R,11R,12S)-6-[(1R)-1-hydroxypropyl]-12-methyl-14,15-dioxa-5-azatetracyclo[7.5.1.01,11.05,10]pentadecan-13-ylidene]-4-methoxy-3-methylfuran-2-one 162868349 Click to see 405.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2007.03.002
(5Z)-5-[(1S,6R,9R,10R,11R,12S)-6-[(1R)-1-hydroxypropyl]-12-methyl-5-oxido-14,15-dioxa-5-azoniatetracyclo[7.5.1.01,11.05,10]pentadecan-13-ylidene]-3-methoxy-4-methylfuran-2-one 101259885 Click to see 421.50 unknown https://doi.org/10.1021/NP070099O
5-[6-(1-Hydroxypropyl)-12-methyl-14,15-dioxa-5-azatetracyclo[7.5.1.01,11.05,10]pentadecan-13-ylidene]-4-methoxy-3-methylfuran-2-one 72812133 Click to see 405.50 unknown https://doi.org/10.1021/NP2004374
https://doi.org/10.1016/S0031-9422(03)00332-7
https://doi.org/10.1021/NP070099O

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