Macaranga schweinfurthii

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Internal ID UUID643fe206acf00960770373
Scientific name Macaranga schweinfurthii
Authority Pax
First published in Bot. Jahrb. Syst. 19: 92 (1894)

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Synonyms Top

Scientific name Authority First published in
Macaranga calophylla Pax Bot. Jahrb. Syst. 43: 221 (1909)
Macaranga lecomtei Beille Mém. Soc. Bot. France 8: 78 (1908)
Macaranga rosea Pax Bot. Jahrb. Syst. 26: 328 (1899)

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • East Tropical Africa
      • Kenya
      • Tanzania
      • Uganda
    • Northeast Tropical Africa
      • Chad
      • Sudan
    • South Tropical Africa
      • Angola
      • Zambia
    • West Tropical Africa
      • Benin
      • Burkina
      • Guinea
      • Ivory Coast
      • Nigeria
    • West-central Tropical Africa
      • Burundi
      • Cameroon
      • Central African Republic
      • Congo
      • Gabon
      • Rwanda
      • Zaïre

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000232237
Tropicos 12804205
KEW urn:lsid:ipni.org:names:351354-1
The Plant List kew-116704
Open Tree Of Life 339743
Observations.org 327946
NCBI Taxonomy 396473
IUCN Red List 200639
IPNI 351354-1
GBIF 3073948
EOL 1155261

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Examination of Raw Samples and Ethanol Extracts of Gerês Propolis Collected in Different Years Caetano AR, Oliveira RD, Pereira RF, Cardoso TV, Cardoso A, Almeida-Aguiar C Plants (Basel) 20-Nov-2023
PMCID:PMC10674325
doi:10.3390/plants12223909
PMID:38005805
Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds Amiri M, Molavi O, Sabetkam S, Jafari S, Montazersaheb S Cancer Cell Int 13-Sep-2023
PMCID:PMC10500939
doi:10.1186/s12935-023-03058-7
PMID:37705051
Resveratrol and Other Natural Oligomeric Stilbenoid Compounds and Their Therapeutic Applications Duta-Bratu CG, Nitulescu GM, Mihai DP, Olaru OT Plants (Basel) 14-Aug-2023
PMCID:PMC10459741
doi:10.3390/plants12162935
PMID:37631147
Substitution of a triazole for the central olefin in biologically active stilbenes Stockdale DP, Beutler JA, Wiemer DF Bioorg Med Chem Lett 09-Sep-2022
PMCID:PMC9563006
doi:10.1016/j.bmcl.2022.128980
PMID:36096344
Schweinfurthin induces ICD without ER stress and caspase activation Zhang R, Neighbors JD, Schell TD, Hohl RJ Oncoimmunology 03-Aug-2022
PMCID:PMC9354771
doi:10.1080/2162402X.2022.2104551
PMID:35936984
Propolis: chemical diversity and challenges in quality control Kasote D, Bankova V, Viljoen AM Phytochem Rev 24-May-2022
PMCID:PMC9128321
doi:10.1007/s11101-022-09816-1
PMID:35645656
RNAseq reveals extensive metabolic disruptions in the sensitive SF-295 cell line treated with schweinfurthins Weissenrieder JS, Weissenkampen JD, Reed JL, Green MV, Zheng C, Neighbors JD, Liu DJ, Hohl RJ Sci Rep 10-Jan-2022
PMCID:PMC8748991
doi:10.1038/s41598-021-04117-7
PMID:35013404
Diet and Activity Budget in Colobus angolensis ruwenzorii at Nabugabo, Uganda: Are They Energy Maximizers? Arseneau-Robar TJ, Changasi AH, Turner E, Teichroeb JA Folia Primatol (Basel) 30-Oct-2020
PMCID:PMC7949237
doi:10.1159/000511046
PMID:33130677
Exploring Antimalarial Herbal Plants across Communities in Uganda Based on Electronic Data Okello D, Kang Y Evid Based Complement Alternat Med 15-Sep-2019
PMCID:PMC6766105
doi:10.1155/2019/3057180
PMID:31636682
Review of Natural Product-Derived Compounds as Potent Antiglioblastoma Drugs Park MN, Song HS, Kim M, Lee MJ, Cho W, Lee HJ, Hwang CH, Kim S, Hwang Y, Kang B, Kim B Biomed Res Int 18-Oct-2017
PMCID:PMC5664208
doi:10.1155/2017/8139848
PMID:29181405
Synthesis of Amide Isosteres of Schweinfurthin-based Stilbenes Stockdale DP, Beutler JA, Wiemer DF Bioorg Med Chem 09-Aug-2017
PMCID:PMC5763908
doi:10.1016/j.bmc.2017.08.016
PMID:28866376
Chimpanzees (Pan troglodytes) Flexibly Use Introduced Species for Nesting and Bark Feeding in a Human-Dominated Habitat McCarthy MS, Lester JD, Stanford CB Int J Primatol 16-Sep-2016
PMCID:PMC5422490
doi:10.1007/s10764-016-9916-y
PMID:28546652
Calcium and P-glycoprotein independent synergism between schweinfurthins and verapamil Sheehy RM, Kuder CH, Bachman Z, Hohl RJ Cancer Biol Ther 05-Jun-2015
PMCID:PMC4622842
doi:10.1080/15384047.2015.1056420
PMID:26046259
Small molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking Bao X, Zheng W, Sugi NH, Agarwala KL, Xu Q, Wang Z, Tendyke K, Lee W, Parent L, Li W, Cheng H, Shen Y, Taylor N, Dezso Z, Du H, Kotake Y, Zhao N, Wang J, Postema M, Woodall-Jappe M, Takase Y, Uenaka T, Kingston DG, Nomoto K Cancer Biol Ther 02-Mar-2015
PMCID:PMC4622430
doi:10.1080/15384047.2015.1019184
PMID:25729885
Recent Advances in the Chemical Composition of Propolis Huang S, Zhang CP, Wang K, Li GQ, Hu FL Molecules 26-Nov-2014
PMCID:PMC6271758
doi:10.3390/molecules191219610
PMID:25432012

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
5-[2-(4-Hydroxyphenyl)ethenyl]-2-(3,7,11-trimethyldodeca-2,6,10-trienyl)benzene-1,3-diol 75113008 Click to see 432.60 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846236/
Schweinfurthin J 45378268 Click to see 432.60 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846236/
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthenes
7-[2-[4-(3,7-dimethylocta-2,6-dienyl)-3,5-dihydroxyphenyl]ethenyl]-1,1,4a-trimethyl-3,4,9,9a-tetrahydro-2H-xanthene-2,3,5-triol 5181 Click to see 548.70 unknown https://doi.org/10.1021/NP980208M
7-[2-[4-(3,7-dimethylocta-2,6-dienyl)-3,5-dihydroxyphenyl]ethenyl]-5-methoxy-1,1,4a-trimethyl-3,4,9,9a-tetrahydro-2H-xanthene-2,3-diol 5182 Click to see 562.70 unknown https://doi.org/10.1021/NP980208M
Schweinfurthin A 643462 Click to see CC(=CCCC(=CCC1=C(C=C(C=C1O)C=CC2=CC3=C(C(=C2)O)OC4(CC(C(C(C4C3)(C)C)O)O)C)O)C)C 548.70 unknown https://doi.org/10.1021/NP980208M
https://doi.org/10.1080/10575639908048487
Schweinfurthin B 643463 Click to see CC(=CCCC(=CCC1=C(C=C(C=C1O)C=CC2=CC3=C(C(=C2)OC)OC4(CC(C(C(C4C3)(C)C)O)O)C)O)C)C 562.70 unknown https://doi.org/10.1080/10575630008043774
https://doi.org/10.1021/NP980208M
Schweinfurthin D 643540 Click to see 580.70 unknown https://doi.org/10.1080/10575630008043774
> Phenylpropanoids and polyketides / Flavonoids / Flavones / 8-prenylated flavones
Isomacarangin 5352097 Click to see 422.50 unknown https://doi.org/10.1080/10575639908048487
> Phenylpropanoids and polyketides / Stilbenes
3-(3,7-Dimethylocta-2,6-dienyl)-5-[2-[4-(3,7-dimethylocta-2,6-dienyl)-3,5-dihydroxyphenyl]ethenyl]benzene-1,2-diol 394689 Click to see 516.70 unknown https://doi.org/10.1021/NP980208M
5-[2-[3-(3,7-Dimethylocta-2,6-dienyl)-4-hydroxyphenyl]ethenyl]benzene-1,3-diol 75113007 Click to see 364.50 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846236/
Schweinfurthin C 5352093 Click to see 516.70 unknown https://doi.org/10.1021/NP980208M
https://doi.org/10.1080/10575639908048487
Schweinfurthin I 45378267 Click to see 364.50 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846236/

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