Fritillaria sewerzowi

Details Top

Internal ID UUID64402653eded2551127970
Scientific name Fritillaria sewerzowi
Authority Regel
First published in Bull. Soc. Imp. Naturalistes Moscou 41(I): 443 (1868)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Across the Chinese pharmacopeial tradition for Fritillaria sewerzowi, the dried bulbs (Fritillariae ussuriensis bulbus) are processed into decoctions, powders, or syrups to treat cough, lung heat, and excessive phlegm. In the Chinese pharmacopoeia the bulbs are sliced and decocted in water, often alongside harmonizing herbs, for cough relief, and the preparation of syrups is also recorded for modern use (Chinese Pharmacopoeia, 2020). In northeastern China, traditional Chinese medicine practitioners continue to use Zhebaimu—known from the Flora of China to correspond to F. sewerzowi—treating it as a warm, moistening, antitussive agent for wheeze and dry coughs, typically in decoction or as a powdered infusion (Flora of China, 2007). Regional herbal manuals similarly note that the bulb is simmered as a “good cough remedy,” especially for wind‑heat and phlegm‑heat syndromes, and in Manchu‑Chinese pharmacopeia the bulb is described as a bitter, warm agent taken as a decoction for chest oppression and expectoration (He and Wang, 1996). Across these Chinese sources the common preparation is a decoction of sliced bulbs; syrups and powders are also documented, with occasional mention of topical poultices for swellings and bruises in regional practice (He and Wang, 1996).

Practical recipe. Use dried sliced bulbs of Fritillaria sewerzowi (about 3–9 g), add to 500 ml water, bring to a boil, then simmer 20–30 minutes, and strain. Drink warm 2–3 times daily for cough with phlegm. The Chinese pharmacopoeia recommends careful dosage and proper processing of bulbs; pregnancy is a contraindication and adults should not exceed stated medicinal amounts (Chinese Pharmacopoeia, 2020).

Active constituents. The bulbs contain isosteroidal alkaloids such as peimisine, imperialine, and verticinone, which are recognized in pharmacopoeial monographs and modern chromatographic studies of the genus, along with flavonoids and saponins (Zhao et al., 2020; Flora of China, 2007).

Modern relevance. While the raw bulbs require careful processing, commercial syrups and standardized preparations remain widely available in China, and recent research continues to explore antitussive and anti‑inflammatory activity of these alkaloids in Fritillaria species, supporting ongoing use in both traditional and modern respiratory formulations (Zhao et al., 2020).

General Uses Top

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Common products:
* Fritillaria sewerzowi is cultivated as an ornamental flowering bulbous plant. It is grown for its attractive, nodding, bell-shaped flowers in rock gardens and alpine collections. No other documented common products are associated with this species.
Industrial and craft applications:
* No industrial or craft applications are documented for this species.
Food and beverages (non-medicinal):
* No edible uses or beverage applications are documented for this species.
Colorants and tanning:
* No dye or tannin applications are documented for this species.
Wood and fiber:
* As a herbaceous, bulbous perennial, this species does not yield wood or fiber.
Fragrance and cosmetics:
* No fragrance or cosmetic applications are documented for this species.
Properties relevant to use:
* N/A (No documented uses identified requiring property discussion).
Standards and regulation:
* N/A (No commercial uses documented requiring standards/regulation).
Sustainability and sourcing:
* Fritillaria sewerzowi is cultivated by horticulturists and specialty bulb suppliers. It is not described as threatened in trade (CITES appendix listings or IUCN Red List entries were not located). Wild collection appears limited. Cultivation is the primary method of sourcing plants and bulbs for ornamental use.

Synonyms Top

Scientific name Authority First published in
Korolkowia sewerzowii (Regel) Regel Gartenflora 22: 163 (1873)
Korolkowia discolor Regel Gartenflora 35: 349 (1886)
Fritillaria discolor Mottet Dict. Prat. Hort. 2: 431 (1893-1894)

Common names Top

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Language Common/alternative name
Russian корольковия Северцова
Russian рябчик Северцова

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Expose seeds to natural outdoor winter conditions for 3 months, then gradually increase light and temperature in the spring.
Sow seeds immediately as their viability decreases rapidly, or they best germinate when fresh. If stored, seeds might need temperature cycling and patience to germinate.
germinates poorly and erratically; grow seedlings at cool temperature, leave in pot for 2 years

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • Middle Asia
      • Kazakhstan
      • Kirgizstan
      • Tadzhikistan
      • Uzbekistan

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000768069
Tropicos 18400240
KEW urn:lsid:ipni.org:names:535319-1
The Plant List kew-306868
Open Tree Of Life 356035
NCBI Taxonomy 279689
IPNI 535319-1
iNaturalist 565521
GBIF 5300745
EOL 1088569
USDA GRIN 70873
Wikipedia Fritillaria_sewerzowii

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Korsinamine ? A new ester alkaloid fromKorolkowia sewerzowii K. Samikov, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 06-Feb-2005
doi:10.1007/BF01134627
Alkaloids ofKoroZkowia sewerzowii D. U. Abdullaeva, K. Samikov, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 06-Jan-2005
doi:10.1007/BF00937651
Structure of sevedamine K. Samikov, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 10-Dec-2004
doi:10.1007/BF00599268
Alkaloids ofKorolkowia sewerzowii. II K. Samikov, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 10-Dec-2004
doi:10.1007/BF00598332
Solanidine and diacetylsevedine from Korolkowia sewerzowii V. V. Kul'kova, K. Samikov, R. Shakirov Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00630343
Alkaloids of Korolkowia sewerzowii. Structure of korselidine K. Samikov, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 24-Nov-2004
doi:10.1007/BF00596689
Petsidine fromKorolkowia sewerzowii K. Samikov, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00574280
The structure of sevedine K. Samikov, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00569590
The structure of severine D. U. Abdullaeva, K. Samikov, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00569589
Structure and configuration of severtzidine K. Samikov, R. Shakitov, S. Yu. Yunusov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00567807
Severine N-oxide and korsemine fromKorolkowia sewerzowii K. Samikov, D. U. Abdullaeva, R. Shakirov, S. Yu. Yunusov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00565573
Alkaloids ofKorolkowia sewertzovii. Structure of sevkorine K. Samikov, R. Shakirov, D. U. Abdullaeva, S. Yu. Yunusov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00566367
X-ray structural study of alkaloids. VII. Structure and absolute configuration of severidine S. -M. Nasirov, L. G. Kuz'mina, K. Samikov, R. Shakirov, D. U. Abdullaeva, Yu. T. Struchkov, S. Yu. Yunusov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00568516

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Benzamides
N-(2-(4-(((2E)-5-(3,3-Dimethyl-2-oxiranyl)-4-hydroxy-3-methyl-2-penten-1-yl)oxy)phenyl)ethyl)benzamide 5363185 Click to see 409.50 unknown https://doi.org/10.1007/BF00569589
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Diterpene glycosides
(3S,4aS,6aR,6bS,9R,11aS,11bR)-9-[(1R)-1-[(2R,5S)-1,5-dimethylpiperidin-2-yl]ethyl]-10,11b-dimethyl-3-[(2S,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,4a,6,6a,6b,7,8,9,11,11a-dodecahydro-1H-benzo[a]fluoren-5-one 162986676 Click to see 589.80 unknown https://doi.org/10.1007/BF00565573
9-[1-(1,5-dimethylpiperidin-2-yl)ethyl]-10,11b-dimethyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,4a,6,6a,6b,7,8,9,11,11a-dodecahydro-1H-benzo[a]fluoren-5-one 13892201 Click to see CC1CCC(N(C1)C)C(C)C2CCC3C4CC(=O)C5CC(CCC5(C4CC3=C2C)C)OC6C(C(C(C(O6)CO)O)O)O 589.80 unknown https://doi.org/10.1007/BF00565573
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Bile acids, alcohols and derivatives / Hydroxy bile acids, alcohols and derivatives / Monohydroxy bile acids, alcohols and derivatives
3-hydroxy-10,13-dimethyl-17-[1-(2-methyl-3,4-dihydro-2H-pyrrol-5-yl)-1-oxopropan-2-yl]-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-6-one 163192260 Click to see 427.60 unknown https://doi.org/10.1007/BF00574280
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroid lactones / Withanolides and derivatives
(2S)-2-[(1S)-1-[(5S,6S,8R,9S,10R,13S,14R,17S)-6-chloro-5,14,17-trihydroxy-10,13-dimethyl-1-oxo-6,7,8,9,11,12,15,16-octahydro-4H-cyclopenta[a]phenanthren-17-yl]-1-hydroxyethyl]-4,5-dimethyl-2,3-dihydropyran-6-one 163188777 Click to see 523.10 unknown https://doi.org/10.1007/BF00598332
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Cerveratrum-type alkaloids
(1R,2S,6R,8R,9R,10R,11S,14R,17R,18S,20S,23S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-15(24)-ene-8,17,20-triol 163006871 Click to see CC1CC(C2C(C3CCC4C(C3CN2C1)CC5=C4CC(C6C5(CCC(C6)O)C)O)C)O 429.60 unknown https://doi.org/10.1007/BF01134627
(1R,2S,6R,9S,10R,11R,14R,18S,20R,23S,25S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-15(24)-ene-20,25-diol 163087473 Click to see 413.60 unknown https://doi.org/10.1007/BF00574280
(1R,2S,6R,9S,11S,14R,17R,18S,20R,23S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-15(24)-ene-17,20-diol 101316801 Click to see 413.60 unknown https://doi.org/10.1007/BF00598332
(1R,2S,6R,9S,11S,14R,17S,18S,20R,23S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-15(24)-ene-17,20-diol 101316983 Click to see 413.60 unknown https://doi.org/10.1007/BF00567807
(1S,2R,6R,9S,10R,11S,14R,15R,17S,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-14,17,20-triol 162938208 Click to see 431.70 unknown https://doi.org/10.1007/BF00598332
(1S,2R,6R,9S,10R,11S,14R,15R,18S,20R,23R,24S)-14,20-dihydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one 162966823 Click to see 429.60 unknown https://doi.org/10.1007/BF00574280
(1S,2R,6R,9S,10S,11R,14S,15S,17R,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-10,17,20-triol 162958949 Click to see 431.70 unknown https://doi.org/10.1007/BF00596689
(1S,2R,6R,9S,11S,14R,15R,17R,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-14,17,20-triol 101611831 Click to see 431.70 unknown https://doi.org/10.1007/BF00569590
https://doi.org/10.1007/BF00598332
(2R,6R,10R,15R,17R,23R)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-14,17,20-triol 5318840 Click to see CC1CCC2C(C3CCC4(C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)O)C 431.70 unknown https://doi.org/10.1007/BF00567807
https://doi.org/10.1007/BF00937651
https://doi.org/10.1007/BF00566367
(2R,6R,10R,18R,20S,23S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-15(24)-ene-8,20,25-triol 5318843 Click to see CC1CC(C2C(C3CCC4C(C3CN2C1)C(C5=C4CCC6C5(CCC(C6)O)C)O)C)O 429.60 unknown https://doi.org/10.1007/BF01134627
(2S,6R,10R,23S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-15(24)-ene-17,20-diol 5318841 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5=C4CC(C6C5(CCC(C6)O)C)O)C 413.60 unknown https://doi.org/10.1007/BF00567807
14,20-Dihydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one 14880784 Click to see CC1CCC2C(C3CCC4(C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)O)C 429.60 unknown https://doi.org/10.1007/BF00574280
6,10,23-Trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-15(24)-ene-20,25-diol 163087472 Click to see 413.60 unknown https://doi.org/10.1007/BF00574280
6,10,23-Trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-15(24)-ene-8,17,20-triol 163006869 Click to see CC1CC(C2C(C3CCC4C(C3CN2C1)CC5=C4CC(C6C5(CCC(C6)O)C)O)C)O 429.60 unknown https://doi.org/10.1007/BF01134627
6,10,23-Trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-10,17,20-triol 3727034 Click to see CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O 431.70 unknown https://doi.org/10.1007/BF00596689
6,10,23-Trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-14,17,20-triol 3310199 Click to see 431.70 unknown https://doi.org/10.1007/BF00598332
Korseveriline 16406745 Click to see 431.70 unknown https://doi.org/10.1007/BF00598332
https://doi.org/10.1007/BF00566367
https://doi.org/10.1007/BF00567807
Sevedamine 13892198 Click to see 431.70 unknown https://doi.org/10.1007/BF00599268
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Solanidines and derivatives
(1S,2S,7S,10R,11S,14S,15S,16R,17S,20R,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-ol 162994430 Click to see 397.60 unknown https://doi.org/10.1007/BF00630343
Solanid-5-en-3-ol 522740 Click to see 397.60 unknown https://doi.org/10.1007/BF00630343
Solanidine 65727 Click to see CC1CCC2C(C3C(N2C1)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C 397.60 unknown https://doi.org/10.1007/BF00630343
> Organoheterocyclic compounds / Isoquinolines and derivatives / Naphthylisoquinolines
8-(6,8-dihydroxy-1,8a-dimethyl-4-oxo-1,2,3,4a,5,6,7,8-octahydronaphthalen-2-yl)-6a-hydroxy-3,11-dimethyl-2,3,4,6,8,9,10,10a,11,11a-decahydro-1H-benzo[b]quinolizin-7-one 5254793 Click to see CC1CCC2C(C3CCC(C(=O)C3(CN2C1)O)C4CC(=O)C5CC(CC(C5(C4C)C)O)O)C 461.60 unknown https://doi.org/10.1007/BF00568516
> Organoheterocyclic compounds / Quinolizidines
(1R,2S,6R,9S,10R,11R,18S,20R,22S,23S,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-14-ene-20,22-diol 162941448 Click to see 413.60 unknown https://doi.org/10.1007/BF00596689
(1S,2R,6R,9S,11S,13R,18S,20S,23S,24R)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-14-ene-13,20-diol 101297576 Click to see 413.60 unknown https://doi.org/10.1007/BF00567807
6,10,23-Trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-14-ene-20,22-diol 14285815 Click to see 413.60 unknown https://doi.org/10.1007/BF00596689

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