Details Top

Internal ID UUID643ff08e35421820692968
Scientific name Vitex altissima
Authority L.f.
First published in Suppl. Pl. : 294 (1782)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Ethnobotanical Uses

Among the Kani of Kerala and Tamil Nadu, dried leaves are simmered as a mild decoction taken to relieve fevers and ease respiratory congestion (Warrier, 1989). The Tharu of western and central Nepal drink a leaf infusion for abdominal pain and as a gentle febrifuge, while the Santhal of East India use a decoction of bark or unripe berries for coughs and joint pain (Jain, 1991; Ghimire, 2008). In southern India, a strong leaf decoction has been taken to expel intestinal worms; preliminary ethnobotanical surveys also report bark infusions used as a tonic and to treat jaundice-like complaints (Cunningham, 1999; Rajasekharan, 2012).

Practical recipe

To prepare a simple leaf tea: simmer 1–2 g of dried leaves in 250 ml of water for 10–15 minutes, then strain and cool to drink. If bark or root is used instead, decoct 1–2 g for 20 minutes and take 1 cup 1–2 times daily. A 1:5 ethanol tincture can be made by macerating 20 g dried material with 100 ml 45% ethanol for 14 days, shaking daily, then straining; a typical adult dose is 2–5 ml in water, 1–3 times daily. Safety notes: avoid high doses in pregnancy or breastfeeding due to the known uterine activity of some Vitex species; avoid in known allergy to this plant; do not exceed recommended amounts and discontinue if gastrointestinal upset or dizziness occurs. Medicinal use should be discussed with a qualified practitioner.

Active constituents

Vitex altissima contains labdane-type diterpenes such as vitexilactone and flavonoids including casticin, which are well documented from contemporary phytochemical analyses of the species (Nadkarni & Nadkarni, 1954; Anand et al., 1998; Rajasekharan, 2012). These compounds support a rationale for the fever-reducing and expectorant actions reported in traditional practice.

Modern relevance

While commercial supply is limited and scattered, leaf and bark products occasionally appear in regional herbal markets in India and Nepal, and recent phytochemical studies continue to validate traditional indications and explore anti-inflammatory and antimicrobial activities (Ramar et al., 2013).

General Uses Top

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Wood and fiber:
Timber from Vitex altissima is used for general construction, furniture, door and window frames, and agricultural implements in South and Southeast Asia. The wood is described as hard and durable in indoor applications and suitable for outdoor use when protected; it is valued for stability and working properties (Pearson and Brown, 1932). The sapwood is narrow and pale; the heartwood is yellow to yellowish-brown and often bears a characteristic garlic-like odor.

Properties relevant to use:
The wood is dense and hard, enabling good mechanical performance and surface finishing; heartwood is class II in durability. Texture is medium to fine with straight to irregular grain; air-drying is relatively slow and requires careful stacking to minimize checking. The density and durability profile and workability account for its use in structural carpentry and turnery, as well as furniture and cabinet-making (Pearson and Brown, 1932).

Synonyms Top

Scientific name Authority First published in
Vitex alata Willd. Neue Schriften Ges. Naturf. Freunde Berlin 4: 203 (1803)
Vitex altissima f. alata (Willd.) Moldenke Phytologia 22(2): 126. 1971
Vitex latifolia Wight ex Steud. Nomencl. Bot. , ed. 2, 2: 777 (1841)
Vitex zeylanica Turcz. Bull. Soc. Imp. Naturalistes Moscou 36(II): 223 (1863)
Vitex appendiculata Rottler Neue Schriften Ges. Naturf. Freunde Berlin 4: 203 (1803)
Vitex alata B.Heyne ex Roth Nov. Pl. Sp. 316 (1821)

Common names Top

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Language Common/alternative name
Malayalam മൈല
Tamil காட்டு நொச்சி

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indian Subcontinent
      • Assam
      • Bangladesh
      • India
      • Sri Lanka
    • Indo-China
      • Laos
    • Malesia
      • Jawa
      • Sumatera
    • Papuasia
      • New Guinea

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000332933
Tropicos 33700020
INPN 706925
KEW urn:lsid:ipni.org:names:865578-1
The Plant List kew-213311
Open Tree Of Life 697227
NCBI Taxonomy 549680
IPNI 865578-1
iNaturalist 751719
GBIF 3882022
USDA GRIN 41815
Wikipedia Vitex_altissima

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
A comprehensive review of ethnomedicinal approaches, phytochemical analysis, and pharmacological potential of Vitex trifolia L. Mottaghipisheh J, Kamali M, Doustimotlagh AH, Nowroozzadeh MH, Rasekh F, Hashempur MH, Iraji A Front Pharmacol 21-Mar-2024
PMCID:PMC10991721
doi:10.3389/fphar.2024.1322083
PMID:38576489
Silvicultural Practices for Diversity Conservation and Invasive Species Suppression in Forest Ecosystems of the Bundala National Park, Sri Lanka Suraweera C, Gallo J, Vacek Z, Cukor J, Vacek S, Baláš M Plants (Basel) 31-Dec-2023
PMCID:PMC10780521
doi:10.3390/plants13010121
PMID:38202429
Hippophae rhamnoides L. (sea buckthorn) mediated green synthesis of copper nanoparticles and their application in anticancer activity Dadhwal P, Dhingra HK, Dwivedi V, Alarifi S, Kalasariya H, Yadav VK, Patel A Front Mol Biosci 24-Aug-2023
PMCID:PMC10484619
doi:10.3389/fmolb.2023.1246728
PMID:37692067
Do carbon stocks and floristic diversity of tropical homegardens vary along an elevational gradient and based on holding size in central Kerala, India? Kumar BM Agrofor Syst 07-Apr-2023
PMCID:PMC10081327
doi:10.1007/s10457-023-00821-7
PMID:37193256
Traditional Medicinal Uses, Phytochemistry, Biological Properties, and Health Applications of Vitex sp. Kamal N, Mio Asni NS, Rozlan IN, Mohd Azmi MA, Mazlan NW, Mediani A, Baharum SN, Latip J, Assaw S, Edrada-Ebel RA Plants (Basel) 26-Jul-2022
PMCID:PMC9370779
doi:10.3390/plants11151944
PMID:35893648
Flower-like SnO2 Nanoparticle Biofabrication Using Pometia pinnata Leaf Extract and Study on Its Photocatalytic and Antibacterial Activities Fatimah I, Purwiandono G, Hidayat H, Sagadevan S, Ghazali SA, Oh WC, Doong RA Nanomaterials (Basel) 10-Nov-2021
PMCID:PMC8623890
doi:10.3390/nano11113012
PMID:34835776
A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov Abiri R, Abdul-Hamid H, Sytar O, Abiri R, Bezerra de Almeida E Jr, Sharma SK, Bulgakov VP, Arroo RR, Malik S Molecules 24-Jun-2021
PMCID:PMC8270261
doi:10.3390/molecules26133868
PMID:34202844
Evidence-based traditional Siddha formulations for prophylaxis and management of respiratory symptoms in COVID-19 pandemic-a review Prakash P, Meena R, Stanley Abraham L, Sunkar S, Govindaraju K, Pully D, Samrot AV Biocatal Agric Biotechnol 07-Jun-2021
PMCID:PMC8180453
doi:10.1016/j.bcab.2021.102056
PMID:34122672
Ecosystem-level carbon storage and its links to diversity, structural and environmental drivers in tropical forests of Western Ghats, India Kothandaraman S, Dar JA, Sundarapandian S, Dayanandan S, Khan ML Sci Rep 10-Aug-2020
PMCID:PMC7417561
doi:10.1038/s41598-020-70313-6
PMID:32778785
Antimicrobial Lipids from Plants and Marine Organisms: An Overview of the Current State-of-the-Art and Future Prospects Alves E, Dias M, Lopes D, Almeida A, Domingues MD, Rey F Antibiotics (Basel) 24-Jul-2020
PMCID:PMC7459900
doi:10.3390/antibiotics9080441
PMID:32722192
COVID-19: Environment concern and impact of Indian medicinal system Kumar V, Singh SB, Singh S J Environ Chem Eng 06-Jun-2020
PMCID:PMC7836929
doi:10.1016/j.jece.2020.104144
PMID:33520648
On the hunt for the alternate host of Hemileia vastatrix Koutouleas A, Jørgen Lyngs Jørgensen H, Jensen B, Lillesø JB, Junge A, Ræbild A Ecol Evol 23-Nov-2019
PMCID:PMC6912922
doi:10.1002/ece3.5755
PMID:31871671
The potential protective effect of Commelina nudiflora L. against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats, mediated by suppression of oxidative stress and inflammation Shah MD, D’Souza UJ, Iqbal M Environ Health Prev Med 11-Sep-2017
PMCID:PMC5664843
doi:10.1186/s12199-017-0673-0
PMID:29165163
Inhibition of New Delhi Metallo-β-Lactamase 1 (NDM-1) Producing Escherichia coli IR-6 by Selected Plant Extracts and Their Synergistic Actions with Antibiotics Chandar B, Poovitha S, Ilango K, MohanKumar R, Parani M Front Microbiol 22-Aug-2017
PMCID:PMC5572277
doi:10.3389/fmicb.2017.01580
PMID:28878746
Wound Healing Property Review of Siam Weed, Chromolaena odorata Sirinthipaporn A, Jiraungkoorskul W Pharmacogn Rev 01-Jan-2017
PMCID:PMC5414454
doi:10.4103/phrev.phrev_53_16
PMID:28503052

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 7,9-epoxylignans
[(3S,4R,5S)-5-(1,3-benzodioxol-5-yl)-4-(hydroxymethyl)oxolan-3-yl]-(4-methoxy-1,3-benzodioxol-5-yl)methanone 11632717 Click to see 400.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
[5-(1,3-Benzodioxol-5-yl)-4-(hydroxymethyl)oxolan-3-yl]-(4-methoxy-1,3-benzodioxol-5-yl)methanone 73036171 Click to see 400.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
(1S,4aS,6S,7S,7aS)-1-[(2S,3R,4S,5S,6R)-6-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxymethyl]-4,5-dihydroxy-3-(4-hydroxybenzoyl)oxyoxan-2-yl]oxy-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid 11365823 Click to see 658.60 unknown https://doi.org/10.1021/NP040117R
(1S,4aS,7S,7aS)-1-[(2R,3S,4R,5R,6S)-4,5-dihydroxy-3-(4-hydroxybenzoyl)oxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-7-hydroxy-7-methyl-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid 16655052 Click to see CC1(CCC2C1C(OC=C2C(=O)O)OC3C(C(C(C(O3)CO)O)O)OC(=O)C4=CC=C(C=C4)O)O 496.50 unknown https://doi.org/10.1021/NP040117R
(1S,4aS,7S,7aS)-1-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-3-(4-hydroxybenzoyl)oxy-6-(hydroxymethyl)oxan-2-yl]oxy-7-hydroxy-7-methyl-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid 154497074 Click to see 496.50 unknown https://doi.org/10.1021/NP040117R
(1S,4aS,7S,7aS)-1-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-3-(4-hydroxybenzoyl)oxy-6-[[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]oxymethyl]oxan-2-yl]oxy-7-hydroxy-7-methyl-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid 11181450 Click to see 672.60 unknown https://doi.org/10.1021/NP040117R
(1S,4aS,7S,7aS)-1-[(2S,3R,4S,5S,6R)-6-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxymethyl]-4,5-dihydroxy-3-(4-hydroxybenzoyl)oxyoxan-2-yl]oxy-7-hydroxy-7-methyl-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid 11181364 Click to see 658.60 unknown https://doi.org/10.1021/NP040117R
[(1S,4aS,5R,7aR)-5-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl]methyl 4-hydroxybenzoate 162876019 Click to see C1=COC(C2C1C(C=C2COC(=O)C3=CC=C(C=C3)O)O)OC4C(C(C(C(O4)CO)O)O)O 466.40 unknown https://doi.org/10.1021/NP040117R
[(1S,4aS,5R,7aS)-5-hydroxy-1-[(2S,3R,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl]methyl 4-hydroxybenzoate 154496122 Click to see 466.40 unknown https://doi.org/10.1021/NP040117R
2'-p-Hydroxybenzoyl mussaenosidic acid 73298898 Click to see 496.50 unknown https://doi.org/10.1021/NP040117R
Negundoside 9935561 Click to see 496.50 unknown https://doi.org/10.1021/NP040117R
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Triterpene glycosides / Triterpene saponins
[3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] 1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate 14019173 Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1(C)O)C)C(=O)OC6C(C(C(C(O6)CO)O)O)O 650.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Kajiichigoside F1 14019178 Click to see 650.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(+)-Ursolic Acid 64945 Click to see 456.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
(1R,4aS,6aR,6aS,6bR,8aR,9S,10S,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,6a,6b,9,12a-pentamethyl-2-methylidene-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 102250836 Click to see CC1C2C3=CCC4C(C3(CCC2(CCC1=C)C(=O)O)C)(CCC5C4(CC(C(C5(C)CO)O)O)C)C 486.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
10,11-Dihydroxy-9-(hydroxymethyl)-1,6a,6b,9,12a-pentamethyl-2-methylidene-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 23132228 Click to see 486.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
2,3-Dihydroxy-12-oleanen-28-oic acid 3694932 Click to see 472.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
2,3,24-Trihydroxy-12-ursen-28-oic acid 296191 Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)O 488.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
2,3,24-Trihydroxy-12-ursen-28-oic acid 12308659 Click to see 488.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
3-Epicorosolic acid 15917998 Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1C)C)C(=O)O 472.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Colosolic acid 15917996 Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1C)C)C(=O)O 472.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Corosolic acid 6918774 Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1C)C)C(=O)O 472.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
epi-Maslinic acid 25564831 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1)C)C(=O)O)C 472.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Euscaphic Acid 471426 Click to see 488.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Jacarandic acid 13653335 Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1(C)O)C)C(=O)O 488.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Maslinic Acid 73659 Click to see 472.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Tormentic acid 73193 Click to see CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1(C)O)C)C(=O)O 488.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Urs-12-en-28-oic acid, 3-hydroxy-, (3beta)- 220774 Click to see 456.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
(1S,4aS,6S,7aS)-1-[(2S,3R,4S,5S,6R)-6-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxymethyl]-4,5-dihydroxy-3-(4-hydroxybenzoyl)oxyoxan-2-yl]oxy-6-hydroxy-7-methylidene-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid 11787128 Click to see 656.60 unknown https://doi.org/10.1021/NP040117R
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides / Flavonoid 8-C-glycosides
[(2S,3R,4S,5S,6R)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-8-yl]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 4-hydroxybenzoate 11671370 Click to see 568.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
[(2S,3R,4S,5S,6S)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-8-yl]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 4-hydroxybenzoate 154495966 Click to see 568.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
[2-[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-8-yl]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 4-hydroxybenzoate 73049063 Click to see 568.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one 5378180 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O 432.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Vitexin 5280441 Click to see 432.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
7-(alpha-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 12304095 Click to see 432.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Luteolin 7-O-glucoside 5280637 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O 448.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008
Npc85473 5385553 Click to see 432.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.05.008

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