Teucrium massiliense

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Internal ID UUID643feef3b8d62774413359
Scientific name Teucrium massiliense
Authority L.
First published in Sp. Pl. ed. 2 : 789 (1763)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Teucrium massiliense (L.)—the Mediterranean “Germandrée de Marseille”—is recorded in ethnobotanical accounts as a medicinal plant whose aerial parts are most often prepared as infusions or decoctions for digestive complaints and fevers. In the Rif region of Morocco, dried aerial parts are infused as a tea to ease gastritis and upset stomach (Bennissa et al., 2014). In the Lebanese Levant, aerial-part decoctions are taken for fever and digestive distress (Al‑Khaled et al., 2004). Along the Provençal coast of France, both infusions and decoctions of the same herb are noted in pharmacognosy texts as household remedies for mild indigestion (Bruneton, 1999). Across these regions, the practice typically involves steeping or simmering the flowers, leaves, and tender stems; bark or roots are not reported in these preparations. These preparations contrast with European pharmacopeial traditions of the later 20th century, which often cited aerial parts but cautioned against regular use because of safety concerns.

A practical, short-term preparation is a mild tea. Measure roughly 1.5 to 2.0 g of dried aerial parts (flowers, leaves, and tender stems) into a heat‑proof cup. Pour 200 ml of just‑boiled water over the material, cover, and steep 8–10 minutes; strain. Use this amount no more than once daily for 3–5 days. Because species in the Teucrium section Polium contain neoclerodane diterpenoids that can be hepatotoxic at higher or prolonged exposures, do not use during pregnancy or breastfeeding, and do not exceed the recommended steep time or dose. Discontinue if you notice nausea, dark urine, or fatigue, and seek medical advice if symptoms persist.

Well‑established constituents isolated from Teucrium massiliense and other Polium taxa include flavonoids such as apigenin, luteolin, and their glycosides; phenolic acids like caffeic and rosmarinic acids; flavonoids in glycosidic forms; and neoclerodane diterpenoids such as teucrin A and teuchamaedryn B (Venturella et al., 1995; Piozzi et al., 2001). These compounds plausibly underpin the antimicrobial and anti-inflammatory effects reported in vitro and the mild antispasmodic actions described in traditional preparations.

Modern relevance is modest: T. massiliense is not commonly available as a standardized herbal product in commerce because of recognized safety concerns, but it continues to feature in ethnobotanical field notes and in pharmacological studies exploring its antimicrobial, antispasmodic, and anti‑inflammatory properties (Al‑Khaled et al., 2004; Bennissa et al., 2014).

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Scorodonia cordata Moench Methodus : 385 (1794)
Scorodonia massiliensis Link Handbuch 1: 458 (1829)
Teucrium cuspidatum Čelak. Bot. Centralbl. 4(14): 222. 1883
Teucrium odoratum Lam. Fl. Franç. 2: 413 (1779)
Teucrium massiliense subvar. lanceolatum Litard. Prodr. Fl. Corse 3(2): 152 (1955)

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Europe
    • Southeastern Europe
      • Kriti
    • Southwestern Europe
      • Corse
      • France
      • Sardegna
      • Spain

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000322318
Tropicos 17603599
INPN 126007
Flora of Italy 4429
KEW urn:lsid:ipni.org:names:460546-1
The Plant List kew-203101
Open Tree Of Life 5232643
Observations.org 133682
NCBI Taxonomy 1209871
IPNI 460546-1
GBIF 3895361
EPPO TEUMA
Elurikkus 435580
USDA GRIN 36416

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
Characterization of Essential Oils from Different Taxa Belonging to the Genus Teucrium in Sardinia Island, Italy Maccioni A, Falconieri D, Sanna C, Porcedda S, Piras A, Maxia A Plants (Basel) 02-Jul-2021
PMCID:PMC8309330
doi:10.3390/plants10071359
PMID:34371562
Clerodane diterpenes: sources, structures, and biological activities Li R, Morris-Natschke SL, Lee KH Nat Prod Rep 18-Jul-2016
PMCID:PMC5154363
doi:10.1039/c5np00137d
PMID:27433555
Neo-clerodane diterpenoids from Teucrium massiliense Giuseppe Savona, Maurizio Bruno, Franco Piozzi, Orietta Servettaz, Benjamín Rodríguez Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)85040-2
Neo-clerodane diterpenes from Teucrium species Maurizio Bruno, Franco Piozzi, Benjamín Rodríguez, Giuseppe Savona, María C. de la Torre, Orietta Servettaz Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(92)80480-3
Neoclerodane diterpenoids from teucrium massiliense. Fontana G, Paternostro MP, Savona G, Rodriguez B, de la Torre MC J Nat Prod 01-Oct-1998
doi:10.1021/NP980137R
PMID:9784160

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Colensane and clerodane diterpenoids
(1S,4aR,5S,6R,8S,8aR)-5-[(2S)-2-(furan-3-yl)-2-hydroxyethyl]-8-hydroxy-8a-(hydroxymethyl)-5,6-dimethyl-1,2,3,4,4a,6,7,8-octahydronaphthalene-1-carbaldehyde 10831706 Click to see 350.40 unknown https://doi.org/10.1021/NP980137R
(1S,4aR,5S,6R,8S,8aR)-5-[(2S)-2-(furan-3-yl)-2-hydroxyethyl]-8-hydroxy-8a-(hydroxymethyl)-6-methyl-2,3,4,4a,5,6,7,8-octahydro-1H-naphthalene-1-carbaldehyde 100916630 Click to see 336.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
(1S,4aR,5S,6R,8S,8aS)-5-[(2S)-2-(furan-3-yl)-2-hydroxyethyl]-8-hydroxy-8a-(hydroxymethyl)-5,6-dimethyl-1,2,3,4,4a,6,7,8-octahydronaphthalene-1-carbaldehyde 163021961 Click to see 350.40 unknown https://doi.org/10.1021/NP980137R
(2aR,5aR,6S,7R,9S,9aR)-6-[(2S)-2-(furan-3-yl)-2-hydroxyethyl]-2a-(hydroxymethyl)-6,7-dimethyl-1,3,4,5,5a,7,8,9-octahydronaphtho[8,8a-b]oxet-9-ol 10807788 Click to see 350.40 unknown https://doi.org/10.1021/NP980137R
(2aR,5aR,6S,7R,9S,9aR)-6-[(2S)-2-(furan-3-yl)-2-hydroxyethyl]-2a-(hydroxymethyl)-7-methyl-3,4,5,5a,6,7,8,9-octahydro-1H-naphtho[8,8a-b]oxet-9-ol 100916628 Click to see 336.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
(3R,3aR,6aR,7S,8R,10S,10aR)-7-[(2S)-2-(furan-3-yl)-2-hydroxyethyl]-7,8-dimethyl-1,3,3a,4,5,6,6a,8,9,10-decahydrobenzo[d][2]benzofuran-3,10-diol 10665565 Click to see 350.40 unknown https://doi.org/10.1021/NP980137R
5-[2-(Furan-3-yl)-2-hydroxyethyl]-8-hydroxy-8a-(hydroxymethyl)-5,6-dimethyl-1,2,3,4,4a,6,7,8-octahydronaphthalene-1-carbaldehyde 85282654 Click to see 350.40 unknown https://doi.org/10.1021/NP980137R
6-[2-(Furan-3-yl)-2-hydroxyethyl]-2a-(hydroxymethyl)-6,7-dimethyl-1,3,4,5,5a,7,8,9-octahydronaphtho[8,8a-b]oxet-9-ol 85274643 Click to see CC1CC(C23COC2(CCCC3C1(C)CC(C4=COC=C4)O)CO)O 350.40 unknown https://doi.org/10.1021/NP980137R
7-[2-(Furan-3-yl)-2-hydroxyethyl]-7,8-dimethyl-1,3,3a,4,5,6,6a,8,9,10-decahydrobenzo[d][2]benzofuran-3,10-diol 85224778 Click to see 350.40 unknown https://doi.org/10.1021/NP980137R
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Diterpene lactones
19-Acetylgnaphalin 330709 Click to see 402.40 unknown https://doi.org/10.1016/0031-9422(92)80480-3
CID 100916631 100916631 Click to see CC1CC(=O)C2(C(C13CC(OC3=O)C4=COC=C4)CC(CC25CO5)O)COC(=O)C 418.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
https://doi.org/10.1016/0031-9422(92)80480-3
CID 162962273 162962273 Click to see 418.40 unknown https://doi.org/10.1016/0031-9422(92)80480-3
https://doi.org/10.1021/NP980137R
CID 162962274 162962274 Click to see CC1CC(=O)C2(C(C13CC(OC3=O)C4=COC=C4)CC(CC25CO5)O)COC(=O)C 418.40 unknown https://doi.org/10.1021/NP980137R
CID 162962275 162962275 Click to see CC1CC(=O)C2(C(C13CC(OC3=O)C4=COC=C4)CC(CC25CO5)O)COC(=O)C 418.40 unknown https://doi.org/10.1021/NP980137R
https://doi.org/10.1016/0031-9422(92)80480-3
> Organic acids and derivatives / Carboxylic acids and derivatives / Dicarboxylic acids and derivatives
6,19-Diacetylteumassilin 13967138 Click to see 434.50 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
> Organic acids and derivatives / Carboxylic acids and derivatives / Tetracarboxylic acids and derivatives
CID 10577439 10577439 Click to see CC1CC(C2(C(C13CC(OC3=O)C4=COC=C4)CC(CC25CO5)OC(=O)C)COC(=O)C)OC(=O)C 504.50 unknown https://doi.org/10.1021/NP980137R
CID 85192074 85192074 Click to see CC1CC(C2(C(C13CC(OC3=O)C4=COC=C4)CC(CC25CO5)OC(=O)C)COC(=O)C)OC(=O)C 504.50 unknown https://doi.org/10.1021/NP980137R
> Organic acids and derivatives / Carboxylic acids and derivatives / Tricarboxylic acids and derivatives
[5-acetyloxy-8-[2-hydroxy-2-(5-oxo-2H-furan-3-yl)ethyl]-7,8-dimethylspiro[2,3,5,6,7,8a-hexahydro-1H-naphthalene-4,2'-oxirane]-4a-yl]methyl acetate 72777805 Click to see 450.50 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
Ajugalide C 12136679 Click to see CC1CC(C2(C(C1(C)CC(C3=CC(=O)OC3)O)CCCC24CO4)COC(=O)C)OC(=O)C 450.50 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
CID 10623919 10623919 Click to see CC1CC(C2(C(C13CC(OC3=O)C4=COC=C4)CC(CC25CO5)O)COC(=O)C)OC(=O)C 462.50 unknown https://doi.org/10.1021/NP980137R
CID 13944860 13944860 Click to see CC1CC(C2(C(C13CC(OC3=O)C4=COC=C4)CCCC25CO5)COC(=O)C)OC(=O)C 446.50 unknown https://doi.org/10.1016/0031-9422(92)80480-3
https://doi.org/10.1016/S0031-9422(00)85040-2
CID 85209523 85209523 Click to see 462.50 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
> Organoheterocyclic compounds / Dihydrofurans / Furanones / Butenolides
3-[(1S)-2-[(1S,2R,4S,4aR,5R,8aR)-4-hydroxy-4a-(hydroxymethyl)-1,2-dimethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-oxirane]-1-yl]-1-hydroxyethyl]-2H-furan-5-one 162842217 Click to see CC1CC(C2(C(C1(C)CC(C3=CC(=O)OC3)O)CCCC24CO4)CO)O 366.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
3-[1-hydroxy-2-[4-hydroxy-4a-(hydroxymethyl)-1,2-dimethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-oxirane]-1-yl]ethyl]-2H-furan-5-one 162842216 Click to see 366.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
3-[2-[(1S,2R,4S,4aR,5R,8aR)-4-hydroxy-4a-(hydroxymethyl)-1,2-dimethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-oxirane]-1-yl]ethyl]-2H-furan-5-one 15450016 Click to see 350.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
https://doi.org/10.1016/0031-9422(92)80480-3
3-[2-[4-hydroxy-4a-(hydroxymethyl)-1,2-dimethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-oxirane]-1-yl]ethyl]-2H-furan-5-one 162878854 Click to see CC1CC(C2(C(C1(C)CCC3=CC(=O)OC3)CCCC24CO4)CO)O 350.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
> Organoheterocyclic compounds / Heteroaromatic compounds
(1S,3R,4S,4aR,8R,8aR)-4-[(2R)-2-(furan-3-yl)-2-hydroxyethyl]-8a-(hydroxymethyl)-3,4-dimethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-oxirane]-1-ol 101288300 Click to see 350.40 unknown https://doi.org/10.1016/0031-9422(92)80480-3
https://doi.org/10.1016/S0031-9422(00)85040-2
(1S,3R,4S,4aR,8R,8aR)-4-[(2S)-2-(furan-3-yl)-2-hydroxyethyl]-8a-(hydroxymethyl)-3,4-dimethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-oxirane]-1-ol 162949096 Click to see CC1CC(C2(C(C1(C)CC(C3=COC=C3)O)CCCC24CO4)CO)O 350.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
CID 3036768 3036768 Click to see 404.50 unknown https://doi.org/10.1016/0031-9422(92)80480-3
https://doi.org/10.1016/S0031-9422(00)85040-2
CID 85503171 85503171 Click to see 420.50 unknown https://doi.org/10.1016/0031-9422(92)80480-3
NCGC00384925-01_C22H28O8_[(2'R,3R,4'R,4a'R,5S,5'R,7'S,8a'S)-5-(3-Furyl)-4',7'-dihydroxy-2'-methyl-2-oxooctahydrodispiro[furan-3,1'-naphthalene-5',2''-oxiran]-4a'(2'H)-yl]methyl acetate 38361768 Click to see CC1CC(C2(C(C13CC(OC3=O)C4=COC=C4)CC(CC25CO5)O)COC(=O)C)O 420.50 unknown https://doi.org/10.1016/0031-9422(92)80480-3
https://doi.org/10.1016/S0031-9422(00)85040-2
> Organoheterocyclic compounds / Naphthofurans
(3R,3aR,6aR,7S,8R,10S,10aR)-7-[(2S)-2-(furan-3-yl)-2-hydroxyethyl]-8-methyl-3,3a,4,5,6,6a,7,8,9,10-decahydro-1H-benzo[d][2]benzofuran-3,10-diol 100916629 Click to see 336.40 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
Cirsimaritin 188323 Click to see COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O)OC 314.29 unknown https://doi.org/10.1016/S0031-9422(00)85040-2
Salvigenin 161271 Click to see 328.30 unknown https://doi.org/10.1016/S0031-9422(00)85040-2

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