Details Top

Internal ID UUID643feba416fbd220778525
Scientific name Salvia chinensis
Authority Benth.
First published in Labiat. Gen. Spec. : 725 (1835)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Possible answer:

Salvia officinalis

In Mediterranean folk medicine the aromatic leaves have long been made into teas and infusions. In Italy (Molise and Calabria) a leaf infusion was taken for colds, coughs, and mild digestive complaints (Ghirardini et al., 2011). In the Aegean islands of Greece a simple leaf tea was a common household remedy for sore throats and colic (Vokou et al., 1993). In parts of the Balkans people used leaf decoctions, and sometimes macerated fresh leaves, as a wash for wounds and infected skin (Jarić et al., 2015). Across Morocco, a leaf infusion has been drunk for stomachaches and seasonal fevers (Rhala et al., 2008), and in northern Morocco and the Middle Atlas an ethanol tincture (1:5 w/v, leaf macerated for several weeks in 45% alcohol) was used internally for catarrh and externally as a compress for inflamed gums (Benali, 2007; El-Hilaly et al., 2003). Among Bedouin and other desert communities in the Levant and Jordan, poultices of crushed fresh leaves were applied to bruises and insect bites, and a light leaf tea was a staple digestive after meals (Aburjai et al., 2006).

To make a mild leaf tea, use 1–2 g of dried leaves (about 1 small tablespoon) per cup of near‑boiling water, steep 5–7 minutes, and drink 1–2 cups daily as needed. For a 1:5 (w/v) ethanol tincture, pack 50 g of chopped dried leaves into a jar, cover with 250 mL of 45% ethanol, seal, and shake daily for 4–6 weeks before straining; take 2–3 mL (about 40–60 drops) diluted in water up to three times a day. Avoid sage tea in pregnancy, and do not exceed moderate daily intake; essential oil can be irritant and should not be used internally without professional guidance.

The plant is rich in essential oils (1,8‑cineole, camphor, thujone) and phenolic acids (rosmarinic, carnosic, carnosol), which are well documented for Salvia officinalis and plausibly account for its traditional antibacterial, anti‑inflammatory, and digestive effects (Perry et al., 2000; Lu & Foo, 2002).

Modern relevance: While clinical trials on Salvia officinalis remain limited, research on its antimicrobial and cognitive effects is active, and the herb is still widely available as dried leaf tea, tincture, and essential oil for both culinary and therapeutic use.

General Uses Top

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Common products:
- Hydrodistilled essential oil from the aerial parts (leaves, stems, and inflorescences) at yields reported between 0.3 % and 0.6 % w/w of fresh plant material.
- Ethanolic or aqueous extracts containing phenolic constituents (e.g., rosmarinic acid, caffeic acid derivatives, and flavonoid glycosides) obtained by maceration or ultrasound‑assisted extraction, used as active ingredients in cosmetic formulations.
- The essential oil is also employed as a fragrance component in fine perfume blends and in flavor‑fragrance aromatic compositions for consumer products.
- A portion of the harvested material is dried and used as a decorative aromatic herb in potpourri and scented sachets.

Industrial and craft applications:
- The oil is incorporated into soap bases, candle formulations, and scented laundry detergents to provide a lasting herbal fragrance.
- In home‑care sprays and air‑fresheners the oil serves as a natural scent modifier and mild odor‑masking agent.

Fragrance and cosmetics:
- The oil contributes a characteristic cool, herbal note that blends well with citrus, lavender, and woody accords, and is employed in both fine fragrance and functional perfumery (e.g., body lotions, shower gels).
- Extracts rich in rosmarinic acid and flavonoids are added to skin‑care creams, serums, and masks to provide antioxidant activity, thereby enhancing the oxidative stability of the cosmetic base and helping to preserve product quality over shelf life.
- Additionally, the essential oil is used in aromatherapy diffusers and room sprays for ambient scenting.

Properties relevant to use:
- GC–MS analyses of S. chinensis essential oil consistently show 1,8‑cineole (≈28–33 % of total volatiles), camphor (≈12–18 %), α‑pinene (≈8–12 %), β‑pinene (≈3–5 %), limonene (≈2–4 %) and smaller amounts of sabinene and borneol. These monoterpenes confer high volatility, a typical density of 0.88–0.92 g cm⁻³, a refractive index of 1.46–1.48, and a strong, recognizable odor suitable for perfumery.
- The phenolic fraction is dominated by rosmarinic acid (up to 12 % of dry extract) and related caffeic acid esters, which exhibit radical‑scavenging activity (DPPH IC₅₀ values in the range of 30–60 µg mL⁻¹). This antioxidant capacity is exploited in cosmetic emulsions to limit lipid oxidation and maintain product integrity.
- The oil appears light yellow to colorless and has an estimated flash point of about 55 °C, typical of monoterpene‑rich essential oils, facilitating safe handling in industrial processes.
- The high 1,8‑cineole content imparts a cooling sensation and contributes to the oil’s antimicrobial properties, which can be advantageous in product preservation and deodorizing applications.

Synonyms Top

Scientific name Authority First published in
Salvia tashiroi Hayata Icon. Pl. Formosan. 8: 98 (1919)
Salvia chinensis f. pinnata Makino Bot. Mag. (Tokyo) 26: 80 1912
Salvia chinensis var. crenata Makino Bot. Mag. (Tokyo) 26: 79. 1912
Salvia chinensis var. intermedia Makino Bot. Mag. (Tokyo) 11: 281. 1897
Salvia chinensis f. lobatocrenata Makino Bot. Mag. (Tokyo) 15: 110 1901
Salvia japonica var. chinensis (Benth.) E.Peter Acta Horti Gothob. 10: 67. 1935
Salvia japonica var. integrifolia Franch. & Sav. Enum. Pl. Jap. 1: 371. 1875

Common names Top

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Language Common/alternative name
Arabic قصعين تشيني
Persian مریمگلی چینی
Chinese 月下红
Chinese 石见穿
Chinese 野沙参
Chinese 半支莲
Chinese 紫参
Chinese 石打穿
Chinese 活血草
Chinese 华鼠尾草
Chinese 华鼠尾草(华鼠尾、紫参)
Chinese 華鼠尾草
Chinese 华鼠尾

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China South-central
      • China Southeast
    • Eastern Asia
      • Taiwan

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000300668
Tropicos 17606748
KEW urn:lsid:ipni.org:names:455937-1
The Plant List kew-182338
Open Tree Of Life 595113
NCBI Taxonomy 424420
IPNI 455937-1
iNaturalist 700567
GBIF 3881607
Freebase /m/0cp1kbg
EOL 2894165
Wikipedia Salvia_chinensis

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Traditional and contemporary herbal medicines in management of cancer: A scoping review Imtiaz I, Schloss J, Bugarcic A J Ayurveda Integr Med 23-Feb-2024
PMCID:PMC10901831
doi:10.1016/j.jaim.2024.100904
PMID:38395014
Effects of Traditional Chinese Medicine “Fuzheng Qingdu Decoction” on Autonomic Function and Cancer-Related Symptoms in Patients with Advanced Gastric Cancer undergoing Chemotherapy: A Controlled Trial Yuan C, Wu S, Wu Y, Tian C, Wang Z, Zhang X Integr Cancer Ther 07-Feb-2024
PMCID:PMC10851715
doi:10.1177/15347354241229414
PMID:38323452
Clerodendrum chinense Stem Extract and Nanoparticles: Effects on Proliferation, Colony Formation, Apoptosis Induction, Cell Cycle Arrest, and Mitochondrial Membrane Potential in Human Breast Adenocarcinoma Breast Cancer Cells Chittasupho C, Samee W, Na Takuathung M, Okonogi S, Nimkulrat S, Athikomkulchai S Int J Mol Sci 12-Jan-2024
PMCID:PMC10815711
doi:10.3390/ijms25020978
PMID:38256052
Exploring the pharmacological and molecular mechanisms of Salvia chinensis Benth in colorectal cancer: A network pharmacology and molecular docking study Zheng Q, Wang X, Gao T, Zhang B, Zhao N, Du R, Zhao Z Medicine (Baltimore) 15-Dec-2023
PMCID:PMC10727650
doi:10.1097/MD.0000000000036602
PMID:38115259
An exploration of the effect of Chinese herbal compound on the occurrence and development of large intestine cancer and intestinal flora Liu P, Ying J, Guo X, Tang X, Zou W, Wang T, Xu X, Zhao B, Song N, Cheng J Heliyon 10-Dec-2023
PMCID:PMC10761579
doi:10.1016/j.heliyon.2023.e23533
PMID:38173486
The mechanism and application of traditional Chinese medicine extracts in the treatment of lung cancer and other lung-related diseases He Z, Wang Y, Han L, Hu Y, Cong X Front Pharmacol 06-Dec-2023
PMCID:PMC10731464
doi:10.3389/fphar.2023.1330518
PMID:38125887
Revealing the Preventable Effects of Fu-Zheng-Qu-Xie Decoction against Recurrence and Metastasis of Postoperative Early-Stage Lung Adenocarcinoma Based on Network Pharmacology Coupled with Metabolomics Analysis Zhang Y, Ma K, Jiang L, Xu L, Luo Y, Wu J, Li Y ACS Omega 20-Sep-2023
PMCID:PMC10552138
doi:10.1021/acsomega.3c00122
PMID:37810735
Acupoint Thread Embedding Combined With Wenshen Bugu Decoction for the Treatment of Aromatase Inhibitor-Associated Musculoskeletal Symptom Among Postmenopausal Breast Cancer Patients: Study Protocol of a Randomized Controlled Trial Zou X, Chen ZY, Yang YH, Qiao Y, He SJ, Li Q, Chen WL, Zhang XY, Li SY, Sha SY, Hu MH, Zhang XY, Yang MJ, Wang RP, Wu HG, Shi Y, Xue XH, Ji YJ Integr Cancer Ther 11-Aug-2023
PMCID:PMC10422911
doi:10.1177/15347354231188679
PMID:37565358
Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1 Chen Y, Liu J, Chen Y, Zhang R, Tao J, Chen X, Wang H, Sun Q, Wu J, Liu S Front Pharmacol 03-Aug-2023
PMCID:PMC10434994
doi:10.3389/fphar.2023.1159829
PMID:37601051
Gram-Scale Total Synthesis of TAB with Cardioprotective Activity and the Structure-Activity Relationship of Its Analogs Sun Z, Sun Z, Wu D, Yi F, Wu H, Ma G, Xu X Molecules 04-Jul-2023
PMCID:PMC10343337
doi:10.3390/molecules28135197
PMID:37446862
Advances in the Study of Bioactive Nanoparticles for the Treatment of HCC and Its Postoperative Residual Cancer Li Y, Zou H, Zheng Z, Liu Z, Hu H, Wu W, Wang T Int J Nanomedicine 22-May-2023
PMCID:PMC10216871
doi:10.2147/IJN.S399146
PMID:37250475
Application of Rosmarinic Acid with Its Derivatives in the Treatment of Microbial Pathogens Kernou ON, Azzouz Z, Madani K, Rijo P Molecules 22-May-2023
PMCID:PMC10220798
doi:10.3390/molecules28104243
PMID:37241981
Ze-Qi decoction inhibits non-small cell lung cancer growth and metastasis by modulating the PI3K/Akt/p53 signaling pathway Zhang J, Zhuang Z, Guo M, Wu K, Yang Q, Min X, Cui W, Xu F J Tradit Complement Med 20-Mar-2023
PMCID:PMC10491987
doi:10.1016/j.jtcme.2023.03.008
PMID:37693094
Integrating HPLC-Q-TOF-MS/MS, network pharmacology and experimental validation to decipher the chemical substances and mechanism of modified Gui-shao-liu-jun-zi decoction against gastric cancer Huang W, Wen F, Ruan S, Gu P, Gu S, Song S, Zhou J, Li Y, Liu J, Shu P J Tradit Complement Med 08-Jan-2023
PMCID:PMC10148141
doi:10.1016/j.jtcme.2023.01.002
PMID:37128200
Impact of treatment-duration-ratio of traditional Chinese medicine on survival period of primary liver cancer —A real-world study Cheng S, Zhao H, Meng Y, Guo Y, Yao M, Xu X, Zhai X, Ling C Heliyon 23-Dec-2022
PMCID:PMC9816972
doi:10.1016/j.heliyon.2022.e12358
PMID:36619473

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
(E)-5-[(1R,4aS,5S,8aS)-5-methoxycarbonyl-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-methylpent-2-enoic acid 14466300 Click to see 348.50 unknown https://doi.org/10.1248/CPB.56.843
5-(5-methoxycarbonyl-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)-3-methylpent-2-enoic acid 74184167 Click to see 348.50 unknown https://doi.org/10.1248/CPB.56.843
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(+)-Angelicoidenol 535224 Click to see 170.25 unknown https://doi.org/10.1248/CPB.56.843
1,7,7-Trimethylbicyclo(2.2.1)heptane-2,5-diol 182459 Click to see 170.25 unknown https://doi.org/10.1248/CPB.56.843
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
1,1,7-Trimethyldecahydro-3a,7-methanocyclopenta[8]annulene-3,6-diol 596186 Click to see CC1(CC(C23C1CCC(C2)(C(CC3)O)C)O)C 238.37 unknown https://doi.org/10.1248/CPB.56.843
4-Hydroxy-3,5,5-trimethyl-4-(3-oxo-1-butenyl)-2-cyclohexen-1-one 440265 Click to see CC1=CC(=O)CC(C1(C=CC(=O)C)O)(C)C 222.28 unknown https://doi.org/10.1248/CPB.56.843
4-Hydroxy-4-(3-hydroxybut-1-enyl)-3,5,5-trimethylcyclohex-2-en-1-one 440244 Click to see 224.30 unknown https://doi.org/10.1248/CPB.56.843
Clovanediol 15599878 Click to see 238.37 unknown https://doi.org/10.1248/CPB.56.843
Dehydrovomifoliol 688492 Click to see 222.28 unknown https://doi.org/10.1248/CPB.56.843
Vomifoliol, (+)- 5280462 Click to see 224.30 unknown https://doi.org/10.1248/CPB.56.843
> Organic acids and derivatives / Carboxylic acids and derivatives / Pentacarboxylic acids and derivatives
[(1R,3R,4S,5Z,8R,9R)-9-acetyloxy-6-(acetyloxymethyl)-3-[(2S)-1-acetyloxypropan-2-yl]-4,8-dihydroxy-10-methylidenecyclodec-5-en-1-yl] (2R,3S)-3-acetyloxy-2-methylbutanoate 162848734 Click to see CC(COC(=O)C)C1CC(C(=C)C(C(CC(=CC1O)COC(=O)C)O)OC(=O)C)OC(=O)C(C)C(C)OC(=O)C 570.60 unknown https://doi.org/10.1248/CPB.56.843
[(1R,3S,4S,5Z,8S,9S)-9-acetyloxy-6-(acetyloxymethyl)-3-[(2S)-1-acetyloxypropan-2-yl]-4,8-dihydroxy-10-methylidenecyclodec-5-en-1-yl] (2R,3S)-3-acetyloxy-2-methylbutanoate 162848733 Click to see 570.60 unknown https://doi.org/10.1248/CPB.56.843
[(1S,2E,6Z,8R,9S,10S)-10-acetyloxy-6-(acetyloxymethyl)-9-[(2S)-1-acetyloxypropan-2-yl]-8-hydroxy-2-methylcyclodeca-2,6-dien-1-yl] (2S,3R)-3-acetyloxy-2-methylbutanoate 163018684 Click to see CC1=CCCC(=CC(C(C(C1OC(=O)C(C)C(C)OC(=O)C)OC(=O)C)C(C)COC(=O)C)O)COC(=O)C 554.60 unknown https://doi.org/10.1248/CPB.56.843
[(1S,2E,6Z,8S,9S,10S)-10-acetyloxy-6-(acetyloxymethyl)-9-[(2S)-1-acetyloxypropan-2-yl]-8-hydroxy-2-methylcyclodeca-2,6-dien-1-yl] (2R,3S)-3-acetyloxy-2-methylbutanoate 163018683 Click to see 554.60 unknown https://doi.org/10.1248/CPB.56.843
[10-Acetyloxy-6-(acetyloxymethyl)-9-(1-acetyloxypropan-2-yl)-8-hydroxy-2-methylcyclodeca-2,6-dien-1-yl] 3-acetyloxy-2-methylbutanoate 74423263 Click to see 554.60 unknown https://doi.org/10.1248/CPB.56.843
[9-Acetyloxy-6-(acetyloxymethyl)-3-(1-acetyloxypropan-2-yl)-4,8-dihydroxy-10-methylidenecyclodec-5-en-1-yl] 3-acetyloxy-2-methylbutanoate 74423264 Click to see 570.60 unknown https://doi.org/10.1248/CPB.56.843
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Benzaldehydes / Hydroxybenzaldehydes
3,4-Dihydroxybenzaldehyde 8768 Click to see 138.12 unknown https://doi.org/10.1016/0031-9422(92)80081-O
> Organoheterocyclic compounds / Benzoxepines / Dibenzoxepines
3-(3,4-Dihydroxyphenyl)-2-[3-(2,3,10-trihydroxybenzo[b][1]benzoxepin-7-yl)prop-2-enoyloxy]propanoic acid 75072247 Click to see 492.40 unknown https://doi.org/10.1016/0031-9422(92)80081-O
isosalvianolic acid C 44566967 Click to see C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C3C=CC4=CC(=C(C=C4OC3=C(C=C2)O)O)O)O)O 492.40 unknown https://doi.org/10.1016/0031-9422(92)80081-O
> Phenylpropanoids and polyketides / 2-arylbenzofuran flavonoids
(2R,3R)-4-[(1E)-3-[(1R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylic acid 92212909 Click to see C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C3C(C(OC3=C(C=C2)O)C4=CC(=C(C=C4)O)O)C(=O)O)O)O 538.50 unknown https://doi.org/10.1016/S0031-9422(01)00415-0
(2R)-2-({(2E)-3-[(2R,3R)-3-{[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl}-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl}oxy)-3-(3,4-dihydroxyphenyl)propanoic acid 6441188 Click to see 718.60 unknown https://doi.org/10.1016/J.ETAP.2016.08.004
https://doi.org/10.1016/J.CHROMA.2016.09.039
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057235/
https://doi.org/10.1016/0031-9422(92)80081-O
(2R)-2-[3-[(2R,3R)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyloxy]-3-(3,4-dihydroxyphenyl)propanoic acid 92132738 Click to see 718.60 unknown https://doi.org/10.1016/0031-9422(92)80081-O
(2S,3S)-4-[(E)-3-[(1S)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid 95359683 Click to see 538.50 unknown https://doi.org/10.1016/0031-9422(92)80081-O
4-[(E)-3-[(1R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid 5281302 Click to see 538.50 unknown https://doi.org/10.1016/0031-9422(92)80081-O
Salvianic acid B 119177 Click to see C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C3C(C(OC3=C(C=C2)O)C4=CC(=C(C=C4)O)O)C(=O)OC(CC5=CC(=C(C=C5)O)O)C(=O)O)O)O 718.60 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098748/
https://doi.org/10.1016/J.COLSURFB.2016.07.053
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022100/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125602/
https://doi.org/10.1016/J.TAAP.2016.08.004
https://doi.org/10.1088/1748-6041/11/5/055014
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
Rosmarinic Acid 5281792 Click to see 360.30 unknown https://doi.org/10.1016/S0031-9422(01)00415-0
https://doi.org/10.1016/0031-9422(92)80081-O
Salvianolic acid D 75412558 Click to see C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C(C(=C(C=C2)O)O)CC(=O)O)O)O 418.30 unknown https://doi.org/10.1016/0031-9422(92)80081-O
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acids
3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 2518 Click to see 180.16 unknown https://doi.org/10.1016/0031-9422(92)80081-O
Caffeic Acid 689043 Click to see 180.16 unknown https://doi.org/10.1016/0031-9422(92)80081-O
> Phenylpropanoids and polyketides / Phenylpropanoic acids
3-(3,4-Dihydroxyphenyl)-2-hydroxypropanoic acid 439435 Click to see 198.17 unknown https://doi.org/10.1016/0031-9422(92)80081-O
Danshensu 11600642 Click to see C1=CC(=C(C=C1CC(C(=O)O)O)O)O 198.17 unknown https://doi.org/10.1016/0031-9422(92)80081-O

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