Isodon liangshanicus

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Common products:
- Dried leaf and stem material of Isodon liangshanicus is supplied to natural‑product chemistry laboratories for the isolation of ent‑kaurane diterpenoids. The material is employed as a reference source for structural elucidation, chemical library development, and method validation in chromatographic and spectroscopic analysis.
- Herbarium voucher specimens of the species are deposited in public herbaria and serve as a taxonomic reference for molecular phylogenetic studies of the genus Isodon. These vouchers provide verifiable DNA for amplification of nuclear and chloroplast markers used in phylogenomics.
- DNA sequences (ITS, trnL‑F, rbcL) derived from voucher specimens are deposited in GenBank, enabling comparative genomics and facilitating species identification in biodiversity surveys.

Properties relevant to use:
- The aerial parts contain a high proportion of ent‑kaurane diterpenoids, a class of tetracyclic diterpenes characterized by a kaurane skeleton. These compounds are lipophilic, extractable with non‑polar organic solvents, and are stable under ambient laboratory conditions, which simplifies extraction, purification, and long‑term storage.
- Phytochemical studies document the presence of specific diterpene structures (e.g., 16‑hydroxy‑ent‑kaurane derivatives) that exhibit consistent UV absorption and distinctive NMR signals, aiding rapid dereplication by HPLC‑UV and LC‑MS.
- The chemical profile of the species (quantified diterpenoid content and minor flavonoids) meets standard criteria for natural‑product reference materials, supporting reproducible preparation of extracts for research applications.

Sustainability and sourcing:
- Isodon liangshanicus is endemic to the Liangshan mountain range in Sichuan, China. It occurs in montane shrubland and forest margins at elevations of 1,800–2,800 m. No commercial cultivation has been reported, and specimens used in research are obtained by wild collection.
- Harvesting is conducted on a limited, non‑commercial scale, typically by local collectors under institutional agreements. Current assessments indicate that the species has not been evaluated for conservation status; however, researchers are encouraged to maintain voucher material, limit collection to a few individuals per site, and avoid habitat disturbance.
- The species’ restricted distribution and reliance on wild collection emphasize the importance of sustainable sampling practices to prevent over‑exploitation and to preserve genetic diversity for future scientific study.

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No reference genome is available on NCBI yet. We are constantly monitoring for new data.

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