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Internal ID UUID643fdf7ac6a14197758109
Scientific name Isodon adenanthus
Authority Kudô
First published in Mem. Fac. Sci. Taihoku Imp. Univ. 2: 123 (1929)

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Synonyms Top

Scientific name Authority First published in
Plectranthus adenanthus Diels Notes Roy. Bot. Gard. Edinburgh 5: 228 (1912)
Plectranthus wui Y.Z.Sun Acta Phytotax. Sin. 11: 55 (1966)
Rabdosia adenantha (Diels) H.Hara J. Jap. Bot. 47: 193 (1972)

Common names Top

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Language Common/alternative name
Chinese 水龙胆草
Chinese 水龙胆草根
Chinese 腺花香茶菜
Chinese 大钮子七
Chinese 路边金
Chinese 铁石元

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000217810
Tropicos 17607261
KEW urn:lsid:ipni.org:names:448563-1
The Plant List kew-102888
Open Tree Of Life 1067800
NCBI Taxonomy 662902
IPNI 448563-1
GBIF 5610159
EOL 2898926

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases Ortiz-Mendoza N, Martínez-Gordillo MJ, Martínez-Ambriz E, Basurto-Peña FA, González-Trujano ME, Aguirre-Hernández E Plants (Basel) 02-Nov-2023
PMCID:PMC10648697
doi:10.3390/plants12213752
PMID:37960108
ent-Kaurane diterpenoids induce apoptosis and ferroptosis through targeting redox resetting to overcome cisplatin resistance Sun Y, Qiao Y, Liu Y, Zhou J, Wang X, Zheng H, Xu Z, Zhang J, Zhou Y, Qian L, Zhang C, Lou H Redox Biol 16-Apr-2021
PMCID:PMC8099784
doi:10.1016/j.redox.2021.101977
PMID:33905957
Peroxiredoxin-1 Overexpression Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and Cardiomyocyte Apoptosis Jiang L, Gong Y, Hu Y, You Y, Wang J, Zhang Z, Wei Z, Tang C Oxid Med Cell Longev 29-Jul-2020
PMCID:PMC7411498
doi:10.1155/2020/2405135
PMID:32802259
Mechanistic Pathways and Molecular Targets of Plant-Derived Anticancer ent-Kaurane Diterpenes Sarwar MS, Xia YX, Liang ZM, Tsang SW, Zhang HJ Biomolecules 16-Jan-2020
PMCID:PMC7023344
doi:10.3390/biom10010144
PMID:31963204
Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis Srinivasan M, Lahiri DK Expert Opin Ther Targets 04-Feb-2015
PMCID:PMC5873291
doi:10.1517/14728222.2014.989834
PMID:25652642
Oxidative Stress, Redox Regulation and Diseases of Cellular Differentiation Ye ZW, Zhang J, Townsend DM, Tew KD Biochim Biophys Acta 15-Nov-2014
PMCID:PMC4433447
doi:10.1016/j.bbagen.2014.11.010
PMID:25445706
Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells Hou JK, Huang Y, He W, Yan ZW, Fan L, Liu MH, Xiao WL, Sun HD, Chen GQ Cell Death Dis 04-Sep-2014
PMCID:PMC4540188
doi:10.1038/cddis.2014.345
PMID:25188510
Studies on chemical constituents of Rabdosia serra ZHENG Qin China Journal of Chinese Materia Medica 22-Sep-2011
doi:10.4268/CJCMM20111611
Two new ent-kaurane diterpenoids from Isodon excisoides Ji Xia Zhang, Yong Xue Wang, Zhi An He, Fu Lin Yan, Han Dong Sun Elsevier BV 31-Dec-2008
doi:10.1016/J.CCLET.2008.10.040
Adenanthusone, a New Ursane Type Nortriterpenoid from Isodon adenanthus. Wei Xiang, Qi‐Shi Song, Hong‐Jie Zhang, Rong‐Tao Li, Zhi Na, Han‐Dong Sun Wiley 22-Mar-2005
doi:10.1002/CHIN.200516159
Adenanthusone, a New Ursane Type Nortriterpenoid from <i>Isodon adenanthus</i> Wei Xiang, Qi‐Shi Song, Hong‐Jie Zhang, Rong‐Tao Li, Zhi Na, Han‐Dong Sun Wiley 24-Nov-2004
doi:10.1002/HLCA.200490255
ent-Kaurene diterpenoids from Isodon oresbius. Xiang W, Li RT, Wang ZY, Li SH, Zhao QS, Zhang HJ, Sun HD Phytochemistry 01-Apr-2004
doi:10.1016/J.PHYTOCHEM.2004.02.022
PMID:15110700
Diterpenoids from Isodon adenantha. Jiang B, Yang H, Li ML, Hou AJ, Han QB, Wang SJ, Li SH, Sun HD J Nat Prod 01-Aug-2002
doi:10.1021/NP020084K
PMID:12193013
Structure of Adenanthin Yun-long Xu, Han-dong Sun, De-zu Wang, Takashi Iwashita, Hajime Komura, Mutsuo Kozuka, Keizo Naya, Isao Kubo Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4039(00)95765-4
Diterpenoids from Isodon adenoloma Zhang Rong Ping, Zhang Hongjie, Lin Zhongwen, Zhen Yulin, Sun Handong Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(92)80450-S

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Very long-chain fatty acids
Octacosanoic acid 10470 Click to see CCCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)O 424.70 unknown https://doi.org/10.4268/CJCMM20111611
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
[(2S,4S,4aS,4bR,5S,7S,10aR)-4,5-dihydroxy-7-(3-hydroxyprop-1-en-2-yl)-1,1,4a-trimethyl-10-oxo-3,4,4b,5,6,7,8,10a-octahydro-2H-phenanthren-2-yl] acetate 11111974 Click to see CC(=O)OC1CC(C2(C3C(CC(CC3=CC(=O)C2C1(C)C)C(=C)CO)O)C)O 392.50 unknown https://doi.org/10.1021/NP020084K
[(2S,4S,4aS,5S,7S,10aR)-4,5-dihydroxy-7-(3-hydroxyprop-1-en-2-yl)-1,1,4a-trimethyl-10-oxo-3,4,4b,5,6,7,8,10a-octahydro-2H-phenanthren-2-yl] acetate 101193824 Click to see CC(=O)OC1CC(C2(C3C(CC(CC3=CC(=O)C2C1(C)C)C(=C)CO)O)C)O 392.50 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Kaurane diterpenoids
(2,8-Diacetyloxy-3,6-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate 3665870 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(C3OC(=O)C)O)(C)C)O)OC(=O)C)C)C(=O)C2=C 492.60 unknown https://doi.org/10.1016/0031-9422(92)80450-S
(2,8-Diacetyloxy-6-hydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate 72245809 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC3OC(=O)C)C(C(CC4OC(=O)C)O)(C)C)C)C(=O)C2=C 476.60 unknown https://doi.org/10.1016/0031-9422(92)80450-S
(2,8-Diacetyloxy-6,15-dihydroxy-5,5,9-trimethyl-14-methylidene-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate 85319341 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC3OC(=O)C)C(C(CC4OC(=O)C)O)(C)C)C)C(C2=C)O 478.60 unknown https://doi.org/10.1016/J.CCLET.2008.10.040
https://doi.org/10.1016/S0367-326X(00)00126-X
(6-Acetyloxy-8,11-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-2-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate 73809281 Click to see CC(=O)OC1CC2C(C(CC(C2(C3C14CC(CC3O)C(=C)C4=O)C)O)OC(=O)C)(C)C 434.50 unknown https://doi.org/10.1016/0031-9422(92)80450-S
[(1R,2R,3R,4R,6S,8S,9R,10S,11S,13S)-2-acetyloxy-3,8,11-trihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-6-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 162998611 Click to see CC(=O)OC1CC(C2(C3C(CC4CC3(C(C(C2C1(C)C)O)OC(=O)C)C(=O)C4=C)O)C)O 450.50 unknown https://doi.org/10.1021/NP020084K
[(1R,2R,3R,4S,6R,7S,9R,10S,11S,13S)-2,6-diacetyloxy-3,7-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 10505290 Click to see CC(=O)OC1CC2CC3(C1C4(CC(C(C(C4C(C3OC(=O)C)O)(C)C)OC(=O)C)O)C)C(=O)C2=C 492.60 unknown https://doi.org/10.1016/J.PHYTOCHEM.2004.02.022
[(1R,2S,4R,6S,8S,9R,10S,11S,13S,15R)-2,8,15-triacetyloxy-6-hydroxy-5,5,9-trimethyl-14-methylidene-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 11060386 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC3OC(=O)C)C(C(CC4OC(=O)C)O)(C)C)C)C(C2=C)OC(=O)C 520.60 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
https://doi.org/10.1021/NP020084K
[(1R,2S,4R,6S,8S,9R,10S,11S,13S)-2-acetyloxy-6,8-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 10950145 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC3OC(=O)C)C(C(CC4O)O)(C)C)C)C(=O)C2=C 434.50 unknown https://doi.org/10.1021/NP020084K
https://doi.org/10.1016/S0367-326X(00)00126-X
[(1S,2R,3R,4R,6S,8S,9R,10S,11S,13S,15R)-2,8-diacetyloxy-3,6,15-trihydroxy-5,5,9-trimethyl-14-methylidene-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 101193825 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(C3OC(=O)C)O)(C)C)O)OC(=O)C)C)C(C2=C)O 494.60 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
https://doi.org/10.1021/NP020084K
[(1S,2R,4R,6S,8S,9S,10S,11S,13R,15R)-2,8,15-triacetyloxy-6-hydroxy-5,5,9-trimethyl-14-methylidene-3-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 163085285 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(=O)C3OC(=O)C)(C)C)O)OC(=O)C)C)C(C2=C)OC(=O)C 534.60 unknown https://doi.org/10.1021/NP020084K
[(1S,2S,4R,6S,8S,9R,10S,11S,13S,15R)-2,8-diacetyloxy-6,15-dihydroxy-5,5,9-trimethyl-14-methylidene-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 10928901 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC3OC(=O)C)C(C(CC4OC(=O)C)O)(C)C)C)C(C2=C)O 478.60 unknown https://doi.org/10.1021/NP020084K
[(1S,2S,4R,6S,8S,9R,10S,11S,13S,15R)-8-acetyloxy-6,11,15-trihydroxy-5,5,9-trimethyl-14-methylidene-2-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 10972161 Click to see CC(=O)OC1CC2C(C(CC(C2(C3C14CC(CC3O)C(=C)C4O)C)OC(=O)C)O)(C)C 436.50 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
https://doi.org/10.1021/NP020084K
[(1S,4R,6S,8R,9S,10S,11R,13R,16R)-8,16-diacetyloxy-6-hydroxy-5,5,9-trimethyl-14-methylidene-3,15-dioxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 163103465 Click to see CC(=O)OC1CC2C(C3(C1C4(C(CC(C(C4C(=O)C3)(C)C)O)OC(=O)C)C)C(=O)C2=C)OC(=O)C 490.50 unknown https://doi.org/10.1021/NP020084K
[(1S,4R,6S,8R,9S,10S,11R,16R)-8,16-diacetyloxy-6-hydroxy-5,5,9-trimethyl-14-methylidene-3,15-dioxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 163187541 Click to see CC(=O)OC1CC2C(C3(C1C4(C(CC(C(C4C(=O)C3)(C)C)O)OC(=O)C)C)C(=O)C2=C)OC(=O)C 490.50 unknown https://doi.org/10.1021/NP020084K
[(2R,4R,6S,8S,9S,10S,11S,13R,15R)-2,8,15-triacetyloxy-6-hydroxy-5,5,9-trimethyl-14-methylidene-3-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 163189225 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(=O)C3OC(=O)C)(C)C)O)OC(=O)C)C)C(C2=C)OC(=O)C 534.60 unknown https://doi.org/10.1021/NP020084K
Adenanthin 15011073 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(=O)C3OC(=O)C)(C)C)O)OC(=O)C)C)C(=O)C2=C 490.50 unknown https://doi.org/10.1016/S0040-4039(00)95765-4
https://doi.org/10.4268/CJCMM20111611
https://doi.org/10.1016/J.PHYTOCHEM.2004.02.022
https://doi.org/10.1016/S0367-326X(00)00126-X
Adenanthin C 10928875 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC3OC(=O)C)C(C(CC4OC(=O)C)O)(C)C)C)C(=O)C2=C 476.60 unknown https://doi.org/10.1021/NP020084K
https://doi.org/10.1016/S0367-326X(00)00126-X
Adenanthin E 10982976 Click to see CC(=O)OC1CC2C(C(CC(C2(C3C14CC(CC3O)C(=C)C4O)C)O)OC(=O)C)(C)C 436.50 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
https://doi.org/10.1021/NP020084K
Adenanthin F 10873754 Click to see CC(=O)OC1CC2C(C(CC(C2(C3C14CC(CC3O)C(=C)C4=O)C)O)OC(=O)C)(C)C 434.50 unknown https://doi.org/10.1021/NP020084K
https://doi.org/10.1016/S0367-326X(00)00126-X
Adenanthin I 11091621 Click to see CC(=O)OC1CC(C2(C3C(CC4CC3(C(C(C2C1(C)C)O)OC(=O)C)C(=O)C4=C)O)C)O 450.50 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
Adenanthin J 11081505 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(=O)C3OC(=O)C)(C)C)O)OC(=O)C)C)C(C2=C)O 492.60 unknown https://doi.org/10.1021/NP020084K
https://doi.org/10.1016/S0367-326X(00)00126-X
Adenanthin K 11081506 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(=O)C3O)(C)C)O)OC(=O)C)C)C(C2=C)OC(=O)C 492.60 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
https://doi.org/10.1021/NP020084K
calcicolin B 44577319 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(=O)C3OC(=O)C)(C)C)O)O)C)C(=O)C2=C 448.50 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
https://doi.org/10.1021/NP020084K
Leucophyllin B 101938882 Click to see CC(=O)OC1CC(C2(C3C(CC4CC3(C(C(=O)C2C1(C)C)OC(=O)C)C(=O)C4=C)O)C)O 448.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2004.02.022
Nervosanin 15139218 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(=O)C3OC(=O)C)(C)C)O)OC(=O)C)C)C(C2=C)OC(=O)C 534.60 unknown https://doi.org/10.1016/S0367-326X(00)00126-X
Weisiensin A 377386 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(C3OC(=O)C)O)(C)C)O)OC(=O)C)C)C(=O)C2=C 492.60 unknown https://doi.org/10.4268/CJCMM20111611
https://doi.org/10.1016/S0367-326X(00)00126-X
Weisiensin A 14355978 Click to see CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(C3OC(=O)C)O)(C)C)O)OC(=O)C)C)C(=O)C2=C 492.60 unknown https://doi.org/10.1021/NP020084K
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Betulin 72326 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)CO 442.70 unknown https://doi.org/10.4268/CJCMM20111611
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(1S,2S,4S,5R,6S,11R,14R,15S,18S,22R,23R)-9-hydroxy-6,10,14,15,22-pentamethyl-21-methylidene-3,24-dioxaheptacyclo[16.5.2.01,15.02,4.05,14.06,11.018,23]pentacos-9-ene-8,25-dione 101136418 Click to see CC1C2C3(CCC1=C)CCC4(C2(C5C(O5)C6C4(CCC7C6(CC(=O)C(=C7C)O)C)C)OC3=O)C 466.60 unknown https://doi.org/10.1002/HLCA.200490255
https://doi.org/10.1002/CHIN.200516159
9-Hydroxy-6,10,14,15,22-pentamethyl-21-methylidene-3,24-dioxaheptacyclo[16.5.2.01,15.02,4.05,14.06,11.018,23]pentacos-9-ene-8,25-dione 162891644 Click to see CC1C2C3(CCC1=C)CCC4(C2(C5C(O5)C6C4(CCC7C6(CC(=O)C(=C7C)O)C)C)OC3=O)C 466.60 unknown https://doi.org/10.1002/HLCA.200490255

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