Mitragyna rotundifolia - Unknown
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Internal ID UUID643fe38f4dda9656340095
Scientific name Mitragyna rotundifolia
Authority Kuntze
First published in Revis. Gen. Pl. 1: 289 (1891)

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Synonyms Top

Scientific name Authority First published in
Mitragyna brunonis (Wall. ex G.Don) Craib Fl. Siam. 2: 11 (1932)
Nauclea brunonis Wall. ex G.Don Gen. Hist. 3: 467 (1834)
Nauclea rotundifolia Roxb. Fl. Ind. 2: 124 (1824)

Common names Top

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Language Common/alternative name
Chinese 帽柱木
Chinese 帽蕊木

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indian Subcontinent
      • Assam
      • Bangladesh
      • East Himalaya
    • Indo-China
      • Andaman Islands
      • Cambodia
      • Laos
      • Myanmar
      • Nicobar Nicobar
      • Thailand
      • Vietnam

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000244941
Tropicos 50158747
KEW urn:lsid:ipni.org:names:756301-1
The Plant List kew-128803
Open Tree Of Life 815055
NCBI Taxonomy 170024
IPNI 756301-1
GBIF 2900479
EOL 1106530

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Ethnobotany and phytochemistry of plants used to treat musculoskeletal disorders among Skaw Karen, Thailand Kantasrila R, Pandith H, Balslev H, Wangpakapattanawong P, Panyadee P, Inta A Pharm Biol 22-Dec-2023
PMCID:PMC10763916
doi:10.1080/13880209.2023.2292261
PMID:38131672
Natural antioxidants that act against Alzheimer’s disease through modulation of the NRF2 pathway: a focus on their molecular mechanisms of action Sidiropoulou GA, Metaxas A, Kourti M Front Endocrinol (Lausanne) 03-Jul-2023
PMCID:PMC10351420
doi:10.3389/fendo.2023.1217730
PMID:37465125
Comparative metabolomics analysis reveals alkaloid repertoires in young and mature Mitragyna speciosa (Korth.) Havil. Leaves Veeramohan R, Zamani AI, Azizan KA, Goh HH, Aizat WM, Razak MF, Yusof NS, Mansor SM, Baharum SN, Ng CL PLoS One 21-Mar-2023
PMCID:PMC10030037
doi:10.1371/journal.pone.0283147
PMID:36943850
Inhibition of Advanced Glycation End-Products by Tamarindus indica and Mitragyna inermis Extracts and Effects on Human Hepatocyte and Fibroblast Viability Ouédraogo RJ, Aleem U, Ouattara L, Nadeem-ul-Haque M, Ouédraogo GA, Jahan H, Shaheen F Molecules 02-Jan-2023
PMCID:PMC9823519
doi:10.3390/molecules28010393
PMID:36615587
The Adverse Cardiovascular Effects and Cardiotoxicity of Kratom (Mitragyna speciosa Korth.): A Comprehensive Review Leong Bin Abdullah MF, Singh D Front Pharmacol 27-Sep-2021
PMCID:PMC8504575
doi:10.3389/fphar.2021.726003
PMID:34646135
Differentiation of Mitragyna speciosa, a narcotic plant, from allied Mitragyna species using DNA barcoding-high-resolution melting (Bar-HRM) analysis Tungphatthong C, Urumarudappa SK, Awachai S, Sooksawate T, Sukrong S Sci Rep 24-Mar-2021
PMCID:PMC7990970
doi:10.1038/s41598-021-86228-9
PMID:33762644
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions Todd DA, Kellogg JJ, Wallace ED, Khin M, Flores-Bocanegra L, Tanna RS, McIntosh S, Raja HA, Graf TN, Hemby SE, Paine MF, Oberlies NH, Cech NB Sci Rep 05-Nov-2020
PMCID:PMC7645423
doi:10.1038/s41598-020-76119-w
PMID:33154449
Medicinal Plants for Treating Musculoskeletal Disorders among Karen in Thailand Kantasrila R, Pandith H, Balslev H, Wangpakapattanawong P, Panyadee P, Inta A Plants (Basel) 28-Jun-2020
PMCID:PMC7412036
doi:10.3390/plants9070811
PMID:32605228
Biochemical Benefits, Diagnosis, and Clinical Risks Evaluation of Kratom Fluyau D, Revadigar N Front Psychiatry 24-Apr-2017
PMCID:PMC5402527
doi:10.3389/fpsyt.2017.00062
PMID:28484399
Secondary Metabolites from Rubiaceae Species Martins D, Nunez CV Molecules 22-Jul-2015
PMCID:PMC6331836
doi:10.3390/molecules200713422
PMID:26205062
New Finding of an Anti-TB Compound in the Genus Marsypopetalum (Annonaceae) from a Traditional Herbal Remedy of Laos Elkington BG, Sydara K, Newsome A, Hwang CH, Lankin DC, Simmler C, Napolitano JG, Ree R, Graham JG, Gyllenhaal C, Bouamanivong S, Souliya O, Pauli GF, Franzblau SG, Soejarto DD J Ethnopharmacol 11-Dec-2013
PMCID:PMC3933013
doi:10.1016/j.jep.2013.11.057
PMID:24333958
Medicinal Plant Active Compounds Produced by UV-B Exposure Kumari R, Prasad MN Sustainable Agriculture Reviews 19-Jan-2013
PMCID:PMC7120792
doi:10.1007/978-94-007-5961-9_8
THE MITRAGYNA SPECIES OF ASIA – Part I. The alkaloids of the leaves of<i>Mitragyna rotundifolia</i>(Roxb.) O. Kuntze<sup>1</sup> E. Shellard, J. Phillipson Georg Thieme Verlag KG 15-Jan-2009
doi:10.1055/S-0028-1100146
Biological evaluation of plants of Laos used in the treatment of tuberculosis in Lao traditional medicine Elkington BG, Southavong B, Sydara K, Souliya O, Vanthanouvong M, Nettavong K, Thammachack B, Pak DH, Riley MC, Franzblau SG, Soejarto DD Pharm Biol 01-Jan-2009
PMCID:PMC3071617
doi:10.1080/13880200802398002
PMID:21479105
THE ALKALOIDS OF MITRAGYNA ROTUNDIFOLIA. I GEORGE BARGER, ELIZABETH DYER, LEWIS J. SARGENT American Chemical Society (ACS) 12-Mar-2005
doi:10.1021/JO01216A008

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Yohimbine alkaloids
3-Isoajmalicine 11416867 Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45 352.40 unknown https://doi.org/10.1055/S-0028-1097976
Lamuran 251561 Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45 352.40 unknown https://doi.org/10.1055/S-0028-1097976
> Organoheterocyclic compounds / Indoles and derivatives / Indoles / 3-alkylindoles
methyl (Z)-2-[(3R,6'S,7'R,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate 163188071 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4OC)NC3=O 414.50 unknown https://doi.org/10.1055/S-0028-1097976
> Organoheterocyclic compounds / Indolizidines
(3R,20S)-19alpha-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester 98363 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O 368.40 unknown https://doi.org/10.1055/S-0028-1097976
Corynoxeine 44568160 Click to see COC=C(C1CC2C3(CCN2CC1C=C)C4=CC=CC=C4NC3=O)C(=O)OC 382.50 unknown https://doi.org/10.1055/S-0028-1097976
Isocorynoxeine 3037448 Click to see COC=C(C1CC2C3(CCN2CC1C=C)C4=CC=CC=C4NC3=O)C(=O)OC 382.50 unknown https://doi.org/10.1055/S-0028-1097976
Isopteropodine 9885603 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O 368.40 unknown https://doi.org/10.1055/S-0028-1097976
methyl (Z)-2-[(3S,6'S,7'R,8'aR)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate 1245595 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O 384.50 unknown https://doi.org/10.1055/S-0028-1097976
https://doi.org/10.1055/S-0028-1100146
methyl 2-(6'-ethenyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate 73081505 Click to see COC=C(C1CC2C3(CCN2CC1C=C)C4=CC=CC=C4NC3=O)C(=O)OC 382.50 unknown https://doi.org/10.1055/S-0028-1097976
methyl 2-(6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate 409518 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O 384.50 unknown https://doi.org/10.1055/S-0028-1097976
https://doi.org/10.1055/S-0028-1100146
methyl 2-[(3R,6'S,7'R,8'aS)-6'-ethyl-4-methoxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate 162890762 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4OC)NC3=O 414.50 unknown https://doi.org/10.1055/S-0028-1097976
Mitrafo;ine 101666873 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O 400.50 unknown https://doi.org/10.1021/JO01216A008

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