Mitragyna diversifolia

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Internal ID UUID643fe38e91307828241521
Scientific name Mitragyna diversifolia
Authority Havil.
First published in J. Linn. Soc., Bot. 33: 71 (1897)

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Synonyms Top

Scientific name Authority First published in
Mamboga capitata Blanco Fl. Filip. : 140 (1837)
Mitragyna javanica Koord. & Valeton Meded. Lands Plantentuin 59: 38 (1902)
Nauclea diversifolia Wall. & G.Don Gen. Hist. 3: 467 (1834)
Stephegyne diversifolia (Wall. & G.Don) Brandis Forest Fl. N.W. India : 263 (1874)
Stephegyne parvifolia S.Vidal Sin. Gen. Pl. Leños. Filip. : t. 56, f. A (1883)
Nauclea africana var. luzoniensis DC. Prodr. [A. P. de Candolle] 4: 345. 1830
Nauclea adina Blanco Fl. Filip., ed. 2. : 102 (1845)
Stephegyne diversifolia (Wall. ex G.Don) Hook.f. Fl. Brit. India 3: 26 1880
Stephegyne tubulosa Fern.-Vill. Fl. Filip., ed. 3. 4(13A): 104 (1880)

Common names Top

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Language Common/alternative name
Thai กระทุ่มนา
Chinese 异叶帽蕊木

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indian Subcontinent
      • Bangladesh
    • Indo-China
      • Cambodia
      • Laos
      • Myanmar
      • Thailand
      • Vietnam
    • Malesia
      • Jawa
      • Malaya
      • Philippines

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000244928
Tropicos 100225428
KEW urn:lsid:ipni.org:names:756293-1
The Plant List kew-128792
Open Tree Of Life 815065
NCBI Taxonomy 170022
IUCN Red List 156220016
IPNI 756293-1
GBIF 2900469
EOL 1106500
Wikipedia Mitragyna_diversifolia

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Classification, biosynthesis, and biological functions of triterpene esters in plants Liu J, Yin X, Kou C, Thimmappa R, Hua X, Xue Z Plant Commun 13-Feb-2024
PMCID:PMC11009366
doi:10.1016/j.xplc.2024.100845
PMID:38356259
Comparative metabolomics analysis reveals alkaloid repertoires in young and mature Mitragyna speciosa (Korth.) Havil. Leaves Veeramohan R, Zamani AI, Azizan KA, Goh HH, Aizat WM, Razak MF, Yusof NS, Mansor SM, Baharum SN, Ng CL PLoS One 21-Mar-2023
PMCID:PMC10030037
doi:10.1371/journal.pone.0283147
PMID:36943850
A Chromosome-Scale Genome Assembly of Mitragyna speciosa (Kratom) and the Assessment of Its Genetic Diversity in Thailand Pootakham W, Yoocha T, Jomchai N, Kongkachana W, Naktang C, Sonthirod C, Chowpongpang S, Aumpuchin P, Tangphatsornruang S Biology (Basel) 12-Oct-2022
PMCID:PMC9598492
doi:10.3390/biology11101492
PMID:36290398
Commodity risk assessment of Acer palmatum plants grafted on Acer davidii from China Bragard C, Baptista P, Chatzivassiliou E, Di Serio F, Jaques Miret JA, Justesen AF, MacLeod A, Magnusson CS, Milonas P, Navas‐Cortes JA, Parnell S, Potting R, Reignault PL, Stefani E, Thulke H, Van der Werf W, Vicent Civera A, Yuen J, Zappalà L, Battisti A, Mas H, Rigling D, Faccoli M, Iacopetti G, Mikulová A, Mosbach‐Schulz O, Stergulc F, Gonthier P EFSA J 12-May-2022
PMCID:PMC9096882
doi:10.2903/j.efsa.2022.7298
PMID:35592020
Differentiation of Mitragyna speciosa, a narcotic plant, from allied Mitragyna species using DNA barcoding-high-resolution melting (Bar-HRM) analysis Tungphatthong C, Urumarudappa SK, Awachai S, Sooksawate T, Sukrong S Sci Rep 24-Mar-2021
PMCID:PMC7990970
doi:10.1038/s41598-021-86228-9
PMID:33762644
Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors Chear NJ, León F, Sharma A, Kanumuri SR, Zwolinski G, Abboud KA, Singh D, Restrepo LF, Patel A, Hiranita T, Ramanathan S, Hampson AJ, McMahon LR, McCurdy CR J Nat Prod 26-Feb-2021
PMCID:PMC8693998
doi:10.1021/acs.jnatprod.0c01055
PMID:33635670
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions Todd DA, Kellogg JJ, Wallace ED, Khin M, Flores-Bocanegra L, Tanna RS, McIntosh S, Raja HA, Graf TN, Hemby SE, Paine MF, Oberlies NH, Cech NB Sci Rep 05-Nov-2020
PMCID:PMC7645423
doi:10.1038/s41598-020-76119-w
PMID:33154449
Assessing the Identity of Commercial Herbs From a Cambodian Market Using DNA Barcoding Cui X, Li W, Wei J, Qi Y, Li R, Yang Y, Shi Y, Meng X, Mi Y, Huot T, Sun W, Zheng X Front Pharmacol 24-Mar-2020
PMCID:PMC7105672
doi:10.3389/fphar.2020.00244
PMID:32265692
Secondary Metabolites from Rubiaceae Species Martins D, Nunez CV Molecules 22-Jul-2015
PMCID:PMC6331836
doi:10.3390/molecules200713422
PMID:26205062
The Mitragyna species of Asia. 8. The alkaloids of the leaves of Mitragyna javanica var. microphylla Koord and Valeton. Shellard EJ, Beckett AH, Tantivatana P, Phillipson JD, Lee CM Planta Med 01-Jan-1970
doi:10.1055/S-0028-1099979
PMID:5618636
Alkaloids from Mitragyna javanica, Koord. and Valeton and Mitragyna hirsuta, Havil. Shellard EJ, Beckett AH, Tantivatana P, Phillipson JD, Lee CM J Pharm Pharmacol 01-Jan-1970
doi:10.1111/J.2042-7158.1966.TB07931.X
PMID:4381868

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Amaryllidaceae alkaloids / Crinine- and Haemanthamine-type amaryllidaceae alkaloids
Augustine 157561 Click to see COC1CC2C3(CCN2CC4=CC5=C(C=C43)OCO5)C6C1O6 301.34 unknown https://doi.org/10.1055/S-0028-1099979
> Alkaloids and derivatives / Corynanthean-type alkaloids
methyl (Z)-2-[(2R,3S,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate 101358740 Click to see 368.50 unknown https://doi.org/10.1111/J.2042-7158.1966.TB07931.X
Methyl 2-(3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate 415704 Click to see 368.50 unknown https://doi.org/10.1111/J.2042-7158.1966.TB07931.X
> Alkaloids and derivatives / Yohimbine alkaloids
Lamuran 251561 Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45 352.40 unknown https://doi.org/10.1055/S-0028-1099979
methyl (1R,15R,16S,20R)-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate 7067845 Click to see 352.40 unknown https://doi.org/10.1055/S-0028-1099979
methyl (1R,15R,16S,20R)-8-methoxy-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,18-pentaene-19-carboxylate 163185917 Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=C4C(=CC=C5)OC 382.50 unknown https://doi.org/10.1055/S-0028-1099979
https://doi.org/10.1111/J.2042-7158.1966.TB07931.X
methyl (1R,15R,16S,20S)-8-methoxy-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,18-pentaene-19-carboxylate 154497013 Click to see 382.50 unknown https://doi.org/10.1055/S-0028-1099979
Methyl 8-methoxy-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,18-pentaene-19-carboxylate 15559991 Click to see 382.50 unknown https://doi.org/10.1111/J.2042-7158.1966.TB07931.X
https://doi.org/10.1055/S-0028-1099979
> Organoheterocyclic compounds / Indoles and derivatives / Indoles / 3-alkylindoles
methyl (1S,4aS,5aS,6S,10aS)-4'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate 162941827 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=C(C=CC=C5OC)NC4=O 398.50 unknown https://doi.org/10.1055/S-0028-1099979
> Organoheterocyclic compounds / Indolizidines
(3R,20S)-19alpha-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester 98363 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O 368.40 unknown https://doi.org/10.1055/S-0028-1099979
11-Methoxyuncarine C 614121 Click to see 398.50 unknown https://doi.org/10.1111/J.2042-7158.1966.TB07931.X
Caboxine A 91895272 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=C(C=C(C=C5)OC)NC4=O 398.50 unknown https://doi.org/10.1111/J.2042-7158.1966.TB07931.X
Isomitraphylline 11726520 Click to see 368.40 unknown https://doi.org/10.1055/S-0028-1099979
Isopteropodine 9885603 Click to see 368.40 unknown https://doi.org/10.1055/S-0028-1099979
methyl (1S,4aS,5aS,6S,10aR)-4'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate 162941828 Click to see 398.50 unknown https://doi.org/10.1055/S-0028-1099979
methyl 4'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate 162941826 Click to see 398.50 unknown https://doi.org/10.1055/S-0028-1099979

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