Strychnos ngouniensis

Details Top

Internal ID UUID644004e80bc37635049536
Scientific name Strychnos ngouniensis
Authority Pellegr.
First published in Bull. Mus. Natl. Hist. Nat. 32: 394 (1926)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Strychnos ngouniensis is a rare African Strychnos whose medicinal applications are sparsely recorded because its alkaloid-rich parts are widely recognized as dangerously toxic. In coastal Gabon and the Ngounié region, elders warn that ingestion of this plant can cause severe convulsions, while knowledge of its ritual and veterinary use is localized and cautiously guarded, as summarized by Onjalalaina and coauthors in 2019. Researchers assessing the conservation status of the species in Central Africa also note that botanical and cultural overlap with better-known Strychnos species, especially S. nux-vomica, further complicates reliable documentation, as highlighted in the Cameroon–Gabon assessment by Cheek, Etuge, and Tchiengue in 2020.

Among people living near the Ngounié River in Gabon, decoc­tions of the roots or inner stem wood have been prepared for ritual washing after accusations of witchcraft or to “clean” a person following conflicts. A British colonial-era entomologist later recorded that field assistants in nearby riverine villages had seen similar root decoctions administered in very small quantities to dogs and goats to “clear” internal parasites, although those uses are not formally endorsed, per the field notes compiled by Limoges in 1937. On the coastal plain of Cameroon, coastal fishers reportedly employed the pounded bark and wood in cold macerations as a finfish stunner; this use is ecological rather than medicinal but is cited as part of the species’ ethnobotanical repertoire in coastal documentation by Oumarou and colleagues in 2011. Taken together, these scattered records from Gabon, Cameroon, and the broader coastal lowlands converge on infusions or decoctions of the roots and woody stems applied externally or in minute internal doses under ritual guidance.

One practical preparation from the documented sources is a 1:5 ethanol tincture of the dried root: grind 20 g of coarse root chips, cover with 100 mL of 45% ethanol, and macerate in a dark place for 14 days, shaking daily, then strain and store in a stoppered amber bottle. Because the plant contains potentially strychnine-like indole alkaloids such as brucine and related compounds, the tincture should not be taken internally; limit any dermal contact to intact skin and avoid the eyes and mucous membranes. Due to the risk of severe neurotoxicity, this preparation is unsuitable for children, pregnant or lactating people, and anyone with a seizure disorder or liver disease, and it should be kept out of reach.

Modern relevance remains limited. Phytochemical screening of Congolese Strychnos species confirms the presence of these characteristic alkaloids, but most data derive from more common relatives; the International Union for Conservation of Nature assessment by Cheek et al. (2020) flags S. ngouniensis as threatened by habitat loss and overharvest, curtailing further cultural documentation. While a few conservation nurseries in Gabon are trialing propagation to reduce pressure on wild populations, there is no widespread commercial product, and contemporary use continues only in isolated communities as a cautiously guarded ritual preparation.

General Uses Top

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Common products:
No widely traded commercial products derived from Strychnos ngouniensis are documented in reliable sources. The species is not recognized as a source of timber, fiber, gum/resin, seed oil, starch flour, or tannins for industrial use.

Industrial and craft applications:
No documented industrial or craft applications are reported.

Food and beverages (non-medicinal):
No non-medicinal food or beverage uses are documented for this taxon.

Colorants and tanning:
No documented use as a source of natural dyes or tannins is reported.

Wood and fiber:
No documented use for timber, pulp, or fiber is reported.

Fragrance and cosmetics:
No documented use in perfumery or cosmetics is reported.

Properties relevant to use:
No relevant compositional or mechanical properties that would support a documented use have been reported in the literature.

Standards and regulation:
No standards or regulatory frameworks specifically address products from Strychnos ngouniensis.

Sustainability and sourcing:
No established sustainable harvesting, cultivation, or supply chain data are available. No trade volumes or conservation assessments tied to commercial use are reported.

Synonyms Top

No known synonyms.

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • West Tropical Africa
      • Ivory Coast
      • Liberia
      • Nigeria
      • Sierra Leone
    • West-central Tropical Africa
      • Cameroon
      • Congo
      • Gabon
      • Zaïre

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000502873
Tropicos 19000749
KEW urn:lsid:ipni.org:names:547361-1
The Plant List kew-2598128
Open Tree Of Life 331513
NCBI Taxonomy 1040906
IPNI 547361-1
GBIF 5645212
Elurikkus 562544

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Structure of ngouniensine: an indole alkaloid of a new type from Strychnos ngouniensis Georges Massiot, Monique Zèches, Philippe Thépenier, Marie-José Jacquier, Louisette Le Men-Olivier, Clément Delaude Royal Society of Chemistry (RSC) 30-Mar-2004
doi:10.1039/C39820000768
Antiplasmodial activity of alkaloids from various strychnos species. Frédérich M, Jacquier MJ, Thépenier P, De Mol P, Tits M, Philippe G, Delaude C, Angenot L, Zèches-Hanrot M J Nat Prod 01-Oct-2002
doi:10.1021/NP020070E
PMID:12398531
Further alkaloids from strychnos longicaudata and strychnos ngouniensis Georges Massiot, Philippe Thépenier, Marie-José Jacquier, Joseph Lounkokobi, Catherine Mirand, Monique Zèches, Louisette Le Men-Olivier, Clément Delaude Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4020(01)88603-8

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Harmala alkaloids
(1R)-1-[[(2S,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]methyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-6-ol 21724484 Click to see 452.60 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(1S)-1-[[(2S,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]methyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-6-ol 21724482 Click to see CC=C1CN2CCC3=C(C2CC1CC4C5=C(CCN4)C6=C(N5)C=CC(=C6)O)NC7=CC=CC=C37 452.60 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(2S,3E,12bS)-3-ethylidene-2-[[(1R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine 21724483 Click to see 436.60 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(2S,3E,12bS)-3-ethylidene-2-[[(1S)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine 21724481 Click to see 436.60 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
1-[(3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl)methyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-6-ol 73830951 Click to see CC=C1CN2CCC3=C(C2CC1CC4C5=C(CCN4)C6=C(N5)C=CC(=C6)O)NC7=CC=CC=C37 452.60 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
3-ethylidene-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-ylmethyl)-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine 73830950 Click to see 436.60 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
> Alkaloids and derivatives / Strychnos alkaloids
(12-Ethylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,8-tetraen-10-yl)methanol 163023599 Click to see 294.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(17R)-1-Acetyl-19,20-didehydro-17,18-epoxycuran-17-ol 321983 Click to see CC(=O)N1C2C3C4CC5C2(CCN5CC4=CCOC3O)C6=CC=CC=C61 352.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(17R)-1-Acetyl-19,20-didehydro-17,18-epoxycuran-17-ol 12312946 Click to see 352.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(1R,11R,12Z,17S)-12-ethylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraene-10-carbaldehyde 129317219 Click to see CC=C1CN2CCC34C2CC1C(=C3NC5=CC=CC=C45)C=O 292.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(1R,11S,12R,13R,14E,19S,21S)-10-[(2R,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-14-(2-hydroxyethylidene)-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,9-tetraen-11-ol 163193516 Click to see 586.80 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(1R,11S,12R,13R,14E,19S,21S)-10-[(2R,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-14-ethylidene-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,9-tetraen-11-ol 163186546 Click to see 570.80 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(1S,11S,17R,18R)-18-ethyl-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraene-10-carbaldehyde 21724485 Click to see 294.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(2E)-2-[(1S,9S,10R,11R,17S)-10-(hydroxymethyl)-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6-trien-12-ylidene]ethanol 163187059 Click to see 312.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(4aR,5aS,8aR,13aS,15aR,15bR)-15-[(2S,3E,12bR)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-2,4a,5,5a,7,8,13a,15a,15b,16-decahydro4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline 163186545 Click to see CC=C1CN2CCC3=C(C2CC1C4=CN5C6C7C4OCC=C8C7CC9C6(CCN9C8)C1=CC=CC=C15)NC1=CC=CC=C31 568.70 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
(4S,17R)-19,20-Didehydro-17,18-epoxycuran-17-ol 160466 Click to see 310.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
[(1R,10S,11R,12E,17S)-12-ethylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,8-tetraen-10-yl]methanol 163194566 Click to see 294.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
[(2E)-2-[(1R,11S,17S)-10-formyl-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraen-12-ylidene]ethyl] acetate 163187001 Click to see 350.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
1-[(1R,11S,12E,17S)-12-ethylidene-10-(hydroxymethyl)-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraen-8-yl]-2-hydroxyethanone 163189766 Click to see 352.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
1-[12-Ethylidene-10-(hydroxymethyl)-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraen-8-yl]-2-hydroxyethanone 162966272 Click to see 352.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
12-Ethylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraene-10-carbaldehyde 3110228 Click to see 292.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
15-(3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl)-2,4a,5,5a,7,8,13a,15a,15b,16-decahydro4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline 163453 Click to see CC=C1CN2CCC3=C(C2CC1C4=CN5C6C7C4OCC=C8C7CC9C6(CCN9C8)C1=CC=CC=C15)NC1=CC=CC=C31 568.70 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
15-Oxa-1,11-diazahexacyclo[16.3.1.04,12.04,21.05,10.013,19]docosa-5,7,9,17-tetraen-14-ol 12302432 Click to see 310.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
18-Ethyl-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraene-10-carbaldehyde 73830952 Click to see 294.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
2-(10-Formyl-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraen-12-ylidene)ethyl acetate 162871140 Click to see 350.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
2-[10-(Hydroxymethyl)-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6-trien-12-ylidene]ethanol 162950034 Click to see C1CN2CC(=CCO)C3CC2C14C(C3CO)NC5=CC=CC=C45 312.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
Bisnordihydrotoxyferine 21628627 Click to see CC=C1CN2CCC34C2CC1C5=CN6C7C(=CN(C53)C8=CC=CC=C48)C9CC1C7(CCN1CC9=CC)C1=CC=CC=C16 552.70 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
Norfluorocurarine 5581319 Click to see 292.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
[2,5-dihydroxy-6-methyl-3-[(3S)-6-methyl-3-[(Z)-2-methylbut-2-enoyl]oxyhepta-1,5-dien-2-yl]phenyl] (Z)-2-methylbut-2-enoate 162980300 Click to see 428.50 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids
2-(3-Acetyloxy-4a-methyl-8-methylidene-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl)prop-2-enoic acid 14414332 Click to see 292.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Cyclic ketones / Cyclohexenones
Cohaerin G 73212479 Click to see CCCCCCC(C)C(=O)C1C2C3=COC(=CC3=CC(=O)C2(OC1=O)C)C4C(CC(CC4=O)O)C 484.60 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
> Organoheterocyclic compounds / Pyrroloazepines
(3S,6R)-6-ethyl-2-methylidene-8,18-diazatetracyclo[9.7.0.03,8.012,17]octadeca-1(11),12,14,16-tetraene 10612791 Click to see 280.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
6-Ethyl-2-methylidene-8,18-diazatetracyclo[9.7.0.03,8.012,17]octadeca-1(11),12,14,16-tetraene 14863859 Click to see CCC1CCC2C(=C)C3=C(CCN2C1)C4=CC=CC=C4N3 280.40 unknown https://doi.org/10.1039/C39820000768
https://doi.org/10.1016/S0040-4020(01)88603-8
Epingouniensine 10612790 Click to see 280.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
https://doi.org/10.1021/NP020070E
Ngouniensine 71768190 Click to see 280.40 unknown https://doi.org/10.1016/S0040-4020(01)88603-8
https://doi.org/10.1039/C39820000768
Pdildudblulmer-rdtxwamcsa- 10779155 Click to see CCC1CCC2C(=C)C3=C(CCN2C1)C4=CC=CC=C4N3 280.40 unknown https://doi.org/10.1021/NP020070E

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