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Haplophyton cimicidum

Table of Contents

Details
Ethnobotanical Use
General Uses
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Gallery
Contributors
Collections

Details Top

Internal ID UUID64403dccc93a4775324857
Scientific name Haplophyton cimicidum
Authority A.DC.
First published in Prodr. 8: 412 (1844)

Ethnobotanical Use Top

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General Uses Top

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Synonyms Top

Scientific name Authority First published in
Rhodocalyx cinereus Miers Apocyn. S. Amer. : 141 (1878)
Echites cimicidus Pav. ex A.DC. Prodr. 8: 413 (1844)
Echites cimicidus Pav. ex Sessé & Moc. Pl. Nov. Hisp. 28 1888
Echites cinereus A.Rich. Hist. Fis. Cuba, Bot. 11: 93 (1850)
Haplophyton cinereum Woodson Ann. Missouri Bot. Gard. 23: 231 (1936)

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Northern America
    • Mexico
      • Mexico Central
      • Mexico Southeast
      • Mexico Southwest

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000979324
Tropicos 1800328
KEW urn:lsid:ipni.org:names:79244-1
The Plant List kew-96249
Open Tree Of Life 5145415
Nature Serve 2.151556
IPNI 79244-1
iNaturalist 157531
GBIF 3169732
EPPO HHPCI
USDA GRIN 18246

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
Title Authors Publication Released IDs
Cimiciphytine and Norcimiciphytine — New Bisindole Alkaloids from Haplophyton cimicidum (Apocyanaceae) Michael P. Cava, M. V. Laksmikantham, Michael J. Mitchell The Japan Institute of Heterocyclic Chemistry 27-Mar-2009
doi:10.3987/R-1978-08-1009
Cimiciduphytine — A New Dimeric Indole Alkaloid from Haplophyton cimicidum (Apocynaceae) Michael P. Cava, Akinbo A. Adesomoju, M. V. Lakshmikantham The Japan Institute of Heterocyclic Chemistry 03-Mar-2009
doi:10.3987/COM-91-5774
Norisohaplophytine and Haplocidiphytine — New Bisindole Alkaloids from Haplophyton cimicidum (Apocynaceae) Michael P. Cava, Akinbo A. Adesomoju, M. V. Lakshmikantham, M. P. Cava The Japan Institute of Heterocyclic Chemistry 02-Mar-2009
doi:10.3987/R-1983-08-1511
Cimicine and Cimicidine, Lactonic Alkaloids from <i>Haplophyton</i> <i>cimicidum</i> M. P. Cava, M. V. Lakshmikantham, S. K. Talapatra, Peter Yates, I. D. Rae, M. Rosenberger, A. G. Szabo, B. Douglas, J. A. Weisbach Canadian Science Publishing 04-May-2006
doi:10.1139/V73-462
Haplophytine. Novel type of indole alkaloid Peter. Yates, F. N. MacLachlan, I. D. Rae, M. Rosenberger, A. G. Szabo, C. R. Willis, M. P. Cava, M. Behforouz, M. V. Lakshmikantham, W. Zeiger American Chemical Society (ACS) 19-Mar-2005
doi:10.1021/JA00804A046
Cimilophytine, a new bisindole alkaloid from Haplophyton cimicidum (Apocynaceae) Akinbo A. Adesomoju, Viresh H. Rawal, M. V. Lakshmikantham, Michael P. Cava American Chemical Society (ACS) 17-Mar-2005
doi:10.1021/JO00166A015
Enantioselective Total Synthesis of Aspidophytine Feng He, Yunxin Bo, Jason D. Altom, E. J. Corey American Chemical Society (ACS) 26-Jul-2002
doi:10.1021/JA9915201
Triterpene constituents of Tabernaemontana laurifolia and Haplophyton cimicidum M.P. Cava, A.K. Shubber, Kota V. Rao Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)86094-X

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Indolonaphthyridine alkaloids
(1R,4R,12R,16S)-9-[(5R,9R,16R)-14,16-dihydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-10(15),11,13-trien-9-yl]-7-hydroxy-8-methoxy-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6,8,10,20-tetraen-18-one 163190667 Click to see 682.80 unknown https://doi.org/10.1021/JO00166A015
(1R,4R,12R,16S)-9-[(9R,16R)-14,16-dihydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-10(15),11,13-trien-9-yl]-7-hydroxy-8-methoxy-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6,8,10,20-tetraen-18-one 102278015 Click to see 682.80 unknown https://doi.org/10.1021/JO00166A015
(1S,4R,12R,16S)-8-hydroxy-9-(14-hydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-5(16),10(15),11,13-tetraen-9-yl)-7-methoxy-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-2,6,8,10-tetraen-18-one 102272391 Click to see CCC(=O)N1C2C=CC34CCCN5C3(C2(CC5)C6=CC(=C(C(=C61)OC)O)C78CCN(C9=C7N(C(=O)CC9)C1=C8C=CC=C1O)C)OC(=O)C4 664.70 unknown https://doi.org/10.3987/COM-91-5774
(1S,4R,12R,16S)-9-[(5R,9R,16R)-14,16-dihydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-10(15),11,13-trien-9-yl]-7,8-dimethoxy-5-methyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-2,6,8,10-tetraen-18-one 163021178 Click to see 654.80 unknown https://doi.org/10.3987/R-1978-08-1009
(1S,4R,12R,16S)-9-[(5R,9R,16R)-14,16-dihydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-10(15),11,13-trien-9-yl]-8-hydroxy-7-methoxy-5-methyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-2,6,8,10-tetraen-18-one 162916988 Click to see 640.70 unknown https://doi.org/10.3987/R-1978-08-1009
(1S,4S,12R,16S)-8-hydroxy-9-[(9R)-14-hydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-5(16),10(15),11,13-tetraen-9-yl]-7-methoxy-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-2,6,8,10-tetraen-18-one 163187550 Click to see 664.70 unknown https://doi.org/10.3987/COM-91-5774
8-Hydroxy-9-(14-hydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-5(16),10(15),11,13-tetraen-9-yl)-7-methoxy-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-2,6,8,10-tetraen-18-one 162931284 Click to see CCC(=O)N1C2C=CC34CCCN5C3(C2(CC5)C6=CC(=C(C(=C61)OC)O)C78CCN(C9=C7N(C(=O)CC9)C1=C8C=CC=C1O)C)OC(=O)C4 664.70 unknown https://doi.org/10.3987/COM-91-5774
9-(14,16-Dihydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-10(15),11,13-trien-9-yl)-7-hydroxy-8-methoxy-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6,8,10,20-tetraen-18-one 73814184 Click to see 682.80 unknown https://doi.org/10.1021/JO00166A015
9-(14,16-Dihydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-10(15),11,13-trien-9-yl)-7,8-dimethoxy-5-methyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-2,6,8,10-tetraen-18-one 73816884 Click to see 654.80 unknown https://doi.org/10.3987/R-1978-08-1009
9-(14,16-Dihydroxy-6-methyl-2-oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-10(15),11,13-trien-9-yl)-8-hydroxy-7-methoxy-5-methyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-2,6,8,10-tetraen-18-one 162916986 Click to see 640.70 unknown https://doi.org/10.3987/R-1978-08-1009
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(10-Hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-4a-yl)methyl octadecanoate 163049162 Click to see 709.20 unknown https://doi.org/10.1016/S0031-9422(00)86094-X
(3beta,13alpha,14beta)-13-Methyl-26-norurs-7-en-3-ol 111220 Click to see 426.70 unknown https://doi.org/10.1016/S0031-9422(00)86094-X
[(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-4a-yl]methyl octadecanoate 163049163 Click to see CCCCCCCCCCCCCCCCCC(=O)OCC12CCC(CC1C3=CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)(C)C 709.20 unknown https://doi.org/10.1016/S0031-9422(00)86094-X
Bauerenol 287684 Click to see CC1CCC2(CCC3(C4=CCC5C(C(CCC5(C4CCC3(C2C1C)C)C)O)(C)C)C)C 426.70 unknown https://doi.org/10.1016/S0031-9422(00)86094-X
> Organoheterocyclic compounds / Indoles and derivatives / Carbazoles
(1R,12S)-12-[(1R,4R,12R,16S)-7,8-dimethoxy-18-oxo-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6,8,10,20-tetraen-9-yl]-7-hydroxy-15-methyl-5,15-diazatetracyclo[10.3.1.01,5.06,11]hexadeca-6(11),7,9-triene-4,16-dione 162957063 Click to see 638.70 unknown https://doi.org/10.3987/R-1983-08-1511
(1R,12S)-7-hydroxy-12-[(1R,4R,12R,16S)-7-hydroxy-8-methoxy-18-oxo-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6,8,10,20-tetraen-9-yl]-5,15-diazatetracyclo[10.3.1.01,5.06,11]hexadeca-6(11),7,9-triene-4,16-dione 162852010 Click to see 666.70 unknown https://doi.org/10.3987/R-1983-08-1511
(1S,12R)-7-hydroxy-12-[(1R,4R,12R,16S)-7-hydroxy-8-methoxy-18-oxo-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6,8,10,20-tetraen-9-yl]-5,15-diazatetracyclo[10.3.1.01,5.06,11]hexadeca-6(11),7,9-triene-4,16-dione 102273139 Click to see 666.70 unknown https://doi.org/10.3987/R-1983-08-1511
12-(7,8-Dimethoxy-18-oxo-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6,8,10,20-tetraen-9-yl)-7-hydroxy-15-methyl-5,15-diazatetracyclo[10.3.1.01,5.06,11]hexadeca-6(11),7,9-triene-4,16-dione 162957061 Click to see 638.70 unknown https://doi.org/10.3987/R-1983-08-1511
7-Hydroxy-12-(7-hydroxy-8-methoxy-18-oxo-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6,8,10,20-tetraen-9-yl)-5,15-diazatetracyclo[10.3.1.01,5.06,11]hexadeca-6(11),7,9-triene-4,16-dione 162852009 Click to see CCC(=O)N1C2CCC34CC(=O)OC35C2(CCN5CC=C4)C6=CC(=C(C(=C61)O)OC)C78CCNC9(C7=O)CCC(=O)N9C1=C8C=CC=C1O 666.70 unknown https://doi.org/10.3987/R-1983-08-1511
7-Hydroxy-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6(11),7,9-trien-18-one 73801194 Click to see 382.50 unknown https://doi.org/10.1139/V73-462
7-Hydroxy-8-methoxy-5-propanoyl-17-oxa-5,15-diazahexacyclo[13.4.3.01,16.04,12.06,11.012,16]docosa-6(11),7,9-trien-18-one 73816885 Click to see 412.50 unknown https://doi.org/10.1139/V73-462
Aspidospermidin-21-oic acid, 3,4-didehydro-19-hydroxy-16,17-dimethoxy-1-methyl-, gamma-lactone 11783895 Click to see 382.50 unknown https://doi.org/10.1021/JA9915201
Aspidospermidin-21-oic acid, 3,4-didehydro-19-hydroxy-16,17-dimethoxy-1-methyl-15-((3aS,7R)-2,3,5,6-tetrahydro-11-hydroxy-4-methyl-1,13-dioxo-1H-3a,7-methanopyrrolo(1,2-a)(1,3)benzodiazocin-7(4H)-yl)-, gamma-lactone 442103 Click to see 652.70 unknown https://doi.org/10.1021/JA00804A046
Cimicidine 21634838 Click to see CCC(=O)N1C2CCC34CCCN5C3(C2(CC5)C6=C1C(=C(C=C6)OC)O)OC(=O)C4 412.50 unknown https://doi.org/10.1139/V73-462
Cimicine 21608708 Click to see 382.50 unknown https://doi.org/10.1139/V73-462

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