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Internal ID UUID64403c938ff33499070931
Scientific name Ancistrocladus ealaensis
Authority J.Léonard
First published in Bull. Soc. Roy. Bot. Belgique 82: 30 (1949)

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Synonyms Top

No known synonyms.

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • West-central Tropical Africa
      • Central African Republic
      • Congo
      • Gabon
      • Zaïre

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000970277
Tropicos 1400010
KEW urn:lsid:ipni.org:names:71938-1
The Plant List kew-8759
Open Tree Of Life 389789
NCBI Taxonomy 714098
IPNI 71938-1
iNaturalist 183309
GBIF 3659010
EOL 6874701

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Computational study to discover potent phytochemical inhibitors against drug target, squalene synthase from Leishmania donovani Wadanambi PM, Mannapperuma U Heliyon 31-May-2021
PMCID:PMC8188062
doi:10.1016/j.heliyon.2021.e07178
PMID:34141935
Biologically Active Isoquinoline Alkaloids covering 2014-2018 Shang XF, Yang CJ, Morris-Natschke SL, Li JC, Yin XD, Liu YQ, Guo X, Peng JW, Goto M, Zhang JY, Lee KH Med Res Rev 29-Jul-2020
PMCID:PMC7554109
doi:10.1002/med.21703
PMID:32729169
Naphthylisoquinoline alkaloids, validated as hit multistage antiplasmodial natural products Moyo P, Shamburger W, van der Watt ME, Reader J, de Sousa AC, Egan TJ, Maharaj VJ, Bringmann G, Birkholtz LM Int J Parasitol Drugs Drug Resist 24-May-2020
PMCID:PMC7270141
doi:10.1016/j.ijpddr.2020.05.003
PMID:32505117
The potential of anti-malarial compounds derived from African medicinal plants: a review of pharmacological evaluations from 2013 to 2019 Bekono BD, Ntie-Kang F, Onguéné PA, Lifongo LL, Sippl W, Fester K, Owono LC Malar J 18-May-2020
PMCID:PMC7236213
doi:10.1186/s12936-020-03231-7
PMID:32423415
An Unusually Broad Series of Seven Cyclombandakamines, Bridged Dimeric Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ealaensis Tshitenge DT, Bruhn T, Feineis D, Mudogo V, Kaiser M, Brun R, Bringmann G Sci Rep 08-Jul-2019
PMCID:PMC6614417
doi:10.1038/s41598-019-46336-z
PMID:31285489
Emerging therapeutic targets for treatment of leishmaniasis Sundar S, Singh B Expert Opin Ther Targets 09-May-2018
PMCID:PMC6047532
doi:10.1080/14728222.2018.1472241
PMID:29718739
Compounds from African Medicinal Plants with Activities Against Selected Parasitic Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis Simoben CV, Ntie-Kang F, Akone SH, Sippl W Nat Prod Bioprospect 09-May-2018
PMCID:PMC5971035
doi:10.1007/s13659-018-0165-y
PMID:29744736
Michellamines A6 and A7, and further mono- and dimeric naphthylisoquinoline alkaloids from a Congolese Ancistrocladus liana and their antiausterity activities against pancreatic cancer cells Lombe BK, Feineis D, Mudogo V, Brun R, Awale S, Bringmann G RSC Adv 31-Jan-2018
PMCID:PMC9078195
doi:10.1039/c8ra00363g
PMID:35542436
Antiplasmodial Ealapasamines A-C,‘Mixed’ Naphthylisoquinoline Dimers from the Central African Liana Ancistrocladus ealaensis Tshitenge DT, Feineis D, Mudogo V, Kaiser M, Brun R, Bringmann G Sci Rep 18-Jul-2017
PMCID:PMC5515985
doi:10.1038/s41598-017-05719-w
PMID:28720905
Activities of Naphthylisoquinoline Alkaloids and Synthetic Analogs against Leishmania major Ponte-Sucre A, Faber JH, Gulder T, Kajahn I, Pedersen SE, Schultheis M, Bringmann G, Moll H Antimicrob Agents Chemother 06-Nov-2006
PMCID:PMC1797665
doi:10.1128/AAC.00936-06
PMID:17088484
Ancistrine, ancistine, ancistrocladeine trois alcaloides isoles de L'ancistrocladus ealaensis J.P. Foucher, J.L. Pousset, A. Cavé Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(75)85253-8
L'ancistrocladonine et L'ancistroealaensine deux alcaloides nouveaux isoles de L'Ancistrocladus ealaensis Jean-Pierre Foucher, Jean-Louis Pousset, Adrien Cavé, André Cavé Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(74)80112-3
Ancistroealaines A and B, two new bioactive naphthylisoquinolines, and related naphthoic acids from Ancistrocladus ealaensis. Bringmann G, Hamm A, Günther C, Michel M, Brun R, Mudogo V J Nat Prod 01-Nov-2000
doi:10.1021/NP000247+
PMID:11087584
Ancistrolikokines A-C: new 5,8'-coupled naphthylisoquinoline alkaloids from Ancistrocladus likoko. Bringmann G, Günther C, Saeb W, Mies J, Wickramasinghe A, Mudogo V, Brun R J Nat Prod 01-Oct-2000
doi:10.1021/NP000199T
PMID:11076547

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Naphthalenes / Naphthalenecarboxylic acids and derivatives / Naphthalenecarboxylic acids
2-Naphthalenecarboxylic acid, 4-hydroxy-5-methoxy- 15559108 Click to see COC1=CC=CC2=CC(=CC(=C21)O)C(=O)O 218.20 unknown https://doi.org/10.1021/NP000199T
2-Naphthalenecarboxylic acid, 4,5-dimethoxy- 21609766 Click to see COC1=CC=CC2=CC(=CC(=C21)OC)C(=O)O 232.23 unknown https://doi.org/10.1021/NP000247+
https://doi.org/10.1021/NP000199T
2-Naphthalenecarboxylic acid, 5-hydroxy-4-methoxy- 10751276 Click to see COC1=C2C(=CC(=C1)C(=O)O)C=CC=C2O 218.20 unknown https://doi.org/10.1021/NP000247+
https://doi.org/10.1021/NP000199T
4-Hydroxy-5-methyl-2-naphthalenecarboxylic acid 73013816 Click to see CC1=C2C(=CC=C1)C=C(C=C2O)C(=O)O 202.21 unknown https://doi.org/10.1021/NP000247+
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Beta-Amyrin 73145 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C)C 426.70 unknown https://doi.org/10.1021/NP000247+
> Organoheterocyclic compounds / Isoquinolines and derivatives / Naphthylisoquinolines
(1R,3R)-5-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-6,8-dimethoxy-1,2,3-trimethyl-3,4-dihydro-1H-isoquinoline 163070817 Click to see CC1CC2=C(C(=CC(=C2C(N1C)C)OC)OC)C3=C4C=CC=C(C4=C(C=C3C)OC)OC 435.60 unknown https://doi.org/10.1016/0031-9422(74)80112-3
(1S,3R)-7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-6-methoxy-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol 162891080 Click to see CC1CC2=CC(=C(C(=C2C(N1)C)O)C3=C4C=CC=C(C4=C(C=C3C)OC)OC)OC 407.50 unknown https://doi.org/10.1016/0031-9422(75)85253-8
(1S,3S)-5-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-6,8-dimethoxy-1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline 11058911 Click to see CC1CC2=C(C(=CC(=C2C(N1)C)OC)OC)C3=C4C=CC=C(C4=C(C=C3C)OC)OC 421.50 unknown https://doi.org/10.1016/0031-9422(74)80112-3
(1S,3S)-7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-8-methoxy-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-6-ol 72375881 Click to see CC1CC2=CC(=C(C(=C2C(N1)C)OC)C3=C4C=CC=C(C4=C(C=C3C)OC)OC)O 407.50 unknown https://doi.org/10.1016/0031-9422(75)85253-8
Ancistrocladeine 135457245 Click to see CC1=CC(=C2C(=C1C3=C4C=C(N=C(C4=C(C=C3O)OC)C)C)C=CC=C2OC)OC 403.50 unknown https://doi.org/10.1016/0031-9422(75)85253-8
ancistroealaine B 10364043 Click to see CC1CC2=C(C(=CC(=C2C(N1)C)OC)OC)C3=C4C=C(C=C(C4=C(C=C3)O)OC)C 407.50 unknown https://doi.org/10.1021/NP000247+
ancistrotanzanine B 10002166 Click to see CC1CC2=C(C(=CC(=C2C(=N1)C)OC)OC)C3=C4C=C(C=C(C4=C(C=C3)OC)OC)C 419.50 unknown https://doi.org/10.1021/NP000247+
https://doi.org/10.1021/NP000199T
Ancistrotectoriline A 10093654 Click to see CC1CC2=C(C(=CC(=C2C(N1)C)OC)OC)C3=C4C=C(C=C(C4=C(C=C3)OC)OC)C 421.50 unknown https://doi.org/10.1021/NP000199T

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