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Neurolaena oaxacana

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Table of Contents

Details
Description
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Biological Material
Contributors
Collections

Details Top

Internal ID UUID643fcf3261b67266646894
Scientific name Neurolaena oaxacana
Authority B.L.Turner
First published in Phytologia 37: 251 (1977)

Description Top

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Synonyms Top

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Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000088227
Tropicos 2734297
KEW urn:lsid:ipni.org:names:169664-2
The Plant List gcc-44566
Open Tree Of Life 7607014
IPNI 169664-2
iNaturalist 289244
GBIF 3096773
EOL 6250469

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
Title Authors Publication Released IDs
Sesquiterpene lactones from Neurolaena lobata Claus M. Passreiter, Detlef Wendisch, Daniel Gondol Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(94)00863-O
New 6-hydroxyflavonoids and their methyl ethers and glycosides from Neurolaena oaxacana Ayhan Ulubelen, Kathleen M. Kerr, Tom J. Mabry Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)83809-1
Thymol-derivate aus Neurolaena-arten Ferdinand Bohlmann, Arvid A. Natu, Kathleen Kerr Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)81897-X
Sesquiterpene lactones from neurolaena oaxacana. Passreiter CM, Sandoval-Ramirez J, Wright CW J Nat Prod 01-Aug-1999
doi:10.1021/NP990038T
PMID:10479310

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Tropane alkaloids
3alpha,6beta-Dihydroxytropane 13855897 Click to see CN1C2CC(CC1C(C2)O)O 157.21 unknown https://doi.org/10.1021/NP990038T
> Benzenoids / Benzene and substituted derivatives / Cumenes
2-Isopropyl-4-methylphenol 78153 Click to see CC1=CC(=C(C=C1)O)C(C)C 150.22 unknown https://doi.org/10.1016/S0031-9422(00)81897-X
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acid esters
(10-Hydroxy-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-1(13)-en-9-yl) 3-methylbutanoate 162860621 Click to see CC1CC2C(C(C(C3(C(=O)C=C1O3)C)O)OC(=O)CC(C)C)C(=C)C(=O)O2 378.40 unknown https://doi.org/10.1021/NP990038T
[(2R,4R,8S,9S,10R,11R)-10-hydroxy-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-1(13)-en-9-yl] 3-methylbutanoate 71812280 Click to see CC1CC2C(C(C(C3(C(=O)C=C1O3)C)O)OC(=O)CC(C)C)C(=C)C(=O)O2 378.40 unknown https://doi.org/10.1021/NP990038T
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones
(10-Hydroxy-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.04,8]tetradeca-1(13),2-dien-9-yl) 3-methylbutanoate 595024 Click to see CC1=CC2C(C(C(C3(C(=O)C=C1O3)C)O)OC(=O)CC(C)C)C(=C)C(=O)O2 376.40 unknown https://doi.org/10.1021/NP990038T
Lobatin B 6440752 Click to see CC1=CC2C(C(C(C3(C(=O)C=C1O3)C)O)OC(=O)CC(C)C)C(=C)C(=O)O2 376.40 unknown https://doi.org/10.1021/NP990038T
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Sesquiterpene lactones / Germacranolides and derivatives
(5-Acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,8,11,11a-hexahydrocyclodeca[b]furan-4-yl) 2-methylpropanoate 73817342 Click to see CC1=CCC(=O)C(C(C(C2C(C1)OC(=O)C2=C)OC(=O)C(C)C)OC(=O)C)(C)O 408.40 unknown https://doi.org/10.1021/NP990038T
(5-Acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,8,11,11a-hexahydrocyclodeca[b]furan-4-yl) 3-methylbutanoate 163027993 Click to see CC1=CCC(=O)C(C(C(C2C(C1)OC(=O)C2=C)OC(=O)CC(C)C)OC(=O)C)(C)O 422.50 unknown https://doi.org/10.1021/NP990038T
(5,6-Dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl) 2-methylpropanoate 162971896 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)O)OC(=O)C(C)C)C(=C)C(=O)O2 366.40 unknown https://doi.org/10.1021/NP990038T
(5,6-Dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl) 3-methylbutanoate 163063107 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)O)OC(=O)CC(C)C)C(=C)C(=O)O2 380.40 unknown https://doi.org/10.1021/NP990038T
[(3aR,4S,5R,6R,8Z,10R,11aR)-4,6-dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-5-yl] 3-methylbutanoate 70697911 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)OC(=O)CC(C)C)O)C(=C)C(=O)O2 380.40 unknown https://doi.org/10.1021/NP990038T
[(3aR,4S,5R,6R,8Z,10R,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] (2S)-2-methylbutanoate 162888557 Click to see CCC(C)C(=O)OC1C2C(CC(C=CC(=O)C(C1OC(=O)C)(C)O)C)OC(=O)C2=C 422.50 unknown https://doi.org/10.1021/NP990038T
[(3aR,4S,5R,6R,8Z,10R,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylpropanoate 162900828 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)OC(=O)C)OC(=O)C(C)C)C(=C)C(=O)O2 408.40 unknown https://doi.org/10.1021/NP990038T
[(3aR,4S,5R,6R,8Z,10R,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 3-methylbutanoate 162918016 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)OC(=O)C)OC(=O)CC(C)C)C(=C)C(=O)O2 422.50 unknown https://doi.org/10.1021/NP990038T
[(3aR,4S,5R,6R,8Z,10R,11aR)-5,6-dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylpropanoate 162971897 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)O)OC(=O)C(C)C)C(=C)C(=O)O2 366.40 unknown https://doi.org/10.1021/NP990038T
[(3aR,4S,5R,6R,8Z,10R,11aR)-5,6-dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 3-methylbutanoate 163063108 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)O)OC(=O)CC(C)C)C(=C)C(=O)O2 380.40 unknown https://doi.org/10.1021/NP990038T
[(3aR,4S,5R,6R,9E,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,8,11,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylpropanoate 162907381 Click to see CC1=CCC(=O)C(C(C(C2C(C1)OC(=O)C2=C)OC(=O)C(C)C)OC(=O)C)(C)O 408.40 unknown https://doi.org/10.1021/NP990038T
[(3aR,4S,5R,6R,9E,11aR)-5,6-dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,8,11,11a-hexahydrocyclodeca[b]furan-4-yl] 3-methylbutanoate 163106145 Click to see CC1=CCC(=O)C(C(C(C2C(C1)OC(=O)C2=C)OC(=O)CC(C)C)O)(C)O 380.40 unknown https://doi.org/10.1021/NP990038T
[(3aS,4R,6R,8Z,10R,11aR)-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 3-methylbutanoate 10406463 Click to see CC1CC2C(C(CC(C(=O)C=C1)(C)O)OC(=O)CC(C)C)C(=C)C(=O)O2 364.40 unknown https://doi.org/10.1021/NP990038T
[(3aS,4S,5R,6R,8Z,10R,11aR)-4,6-dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-5-yl] 3-methylbutanoate 101921667 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)OC(=O)CC(C)C)O)C(=C)C(=O)O2 380.40 unknown https://doi.org/10.1021/NP990038T
[(3aS,4S,5R,6R,8Z,10R,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylbutanoate 100963995 Click to see CCC(C)C(=O)OC1C2C(CC(C=CC(=O)C(C1OC(=O)C)(C)O)C)OC(=O)C2=C 422.50 unknown https://doi.org/10.1016/0031-9422(94)00863-O
[(3aS,4S,5R,6R,8Z,10R,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylpropanoate 100963994 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)OC(=O)C)OC(=O)C(C)C)C(=C)C(=O)O2 408.40 unknown https://doi.org/10.1021/NP990038T
https://doi.org/10.1016/0031-9422(94)00863-O
[(3aS,4S,5R,6R,8Z,10R,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 3-methylbutanoate 10454918 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)OC(=O)C)OC(=O)CC(C)C)C(=C)C(=O)O2 422.50 unknown https://doi.org/10.1021/NP990038T
[(3aS,4S,5R,6R,8Z,10R,11aR)-5,6-dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylpropanoate 163190205 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)O)OC(=O)C(C)C)C(=C)C(=O)O2 366.40 unknown https://doi.org/10.1021/NP990038T
[(3aS,4S,5R,6R,8Z,10R,11aR)-5,6-dihydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,10,11,11a-hexahydrocyclodeca[b]furan-4-yl] 3-methylbutanoate 70697907 Click to see CC1CC2C(C(C(C(C(=O)C=C1)(C)O)O)OC(=O)CC(C)C)C(=C)C(=O)O2 380.40 unknown https://doi.org/10.1021/NP990038T
[(3aS,4S,5R,6R,9E,11aR)-6-hydroxy-6,10-dimethyl-3-methylidene-4-(2-methylpropoxy)-2,7-dioxo-3a,4,5,8,11,11a-hexahydrocyclodeca[b]furan-5-yl] acetate 101035411 Click to see CC1=CCC(=O)C(C(C(C2C(C1)OC(=O)C2=C)OCC(C)C)OC(=O)C)(C)O 394.50 unknown https://doi.org/10.1016/0031-9422(94)00863-O
[(3aS,4S,5R,6R,9Z,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,8,11,11a-hexahydrocyclodeca[b]furan-4-yl] 2-methylpropanoate 162907380 Click to see CC1=CCC(=O)C(C(C(C2C(C1)OC(=O)C2=C)OC(=O)C(C)C)OC(=O)C)(C)O 408.40 unknown https://doi.org/10.1021/NP990038T
[(3aS,4S,5R,6R,9Z,11aR)-5-acetyloxy-6-hydroxy-6,10-dimethyl-3-methylidene-2,7-dioxo-3a,4,5,8,11,11a-hexahydrocyclodeca[b]furan-4-yl] 3-methylbutanoate 101921669 Click to see CC1=CCC(=O)C(C(C(C2C(C1)OC(=O)C2=C)OC(=O)CC(C)C)OC(=O)C)(C)O 422.50 unknown https://doi.org/10.1021/NP990038T
> Organic acids and derivatives / Carboxylic acids and derivatives / Tricarboxylic acids and derivatives
(10-Acetyloxy-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-1(13)-en-9-yl) 3-methylbutanoate 162965914 Click to see CC1CC2C(C(C(C3(C(=O)C=C1O3)C)OC(=O)C)OC(=O)CC(C)C)C(=C)C(=O)O2 420.50 unknown https://doi.org/10.1021/NP990038T
[(2R,4R,8S,9S,10R,11R)-10-acetyloxy-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-1(13)-en-9-yl] 3-methylbutanoate 101035409 Click to see CC1CC2C(C(C(C3(C(=O)C=C1O3)C)OC(=O)C)OC(=O)CC(C)C)C(=C)C(=O)O2 420.50 unknown https://doi.org/10.1021/NP990038T
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides
2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-6-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 162855828 Click to see COC1=C(C(=C2C(=C1)OC(=C(C2=O)OC)C3=CC(=C(C=C3)O)O)O)OC4C(C(C(C(O4)CO)O)O)O 508.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 53463177 Click to see COC1=C(C(=C2C(=C1)OC(=C(C2=O)OC)C3=CC(=C(C=C3)O)O)O)OC4C(C(C(C(O4)CO)O)O)O 508.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
5,7-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 163038590 Click to see COC1=C(OC2=C(C1=O)C(=C(C(=C2)O)OC3C(C(C(C(O3)CO)O)O)O)O)C4=CC=C(C=C4)O 478.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 74978449 Click to see COC1=C(OC2=C(C1=O)C(=C(C(=C2)O)OC3C(C(C(C(O3)CO)O)O)O)O)C4=CC=C(C=C4)O 478.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 5462193 Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O 448.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
Astragalin 5282102 Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O 448.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
2-(3,4-dihydroxyphenyl)-5,6-dihydroxy-3-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 21599446 Click to see COC1=C(OC2=CC(=C(C(=C2C1=O)O)O)OC3C(C(C(C(O3)CO)O)O)O)C4=CC(=C(C=C4)O)O 494.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
2-(3,4-Dihydroxyphenyl)-5,6-dihydroxy-3-methoxy-7-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 73812467 Click to see COC1=C(OC2=CC(=C(C(=C2C1=O)O)O)OC3C(C(C(C(O3)CO)O)O)O)C4=CC(=C(C=C4)O)O 494.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
5,6-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 163070633 Click to see COC1=C(OC2=CC(=C(C(=C2C1=O)O)O)OC3C(C(C(C(O3)CO)O)O)O)C4=CC=C(C=C4)O 478.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
5,6-Dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-7-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 74978450 Click to see COC1=C(OC2=CC(=C(C(=C2C1=O)O)O)OC3C(C(C(C(O3)CO)O)O)O)C4=CC=C(C=C4)O 478.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
Patuletin 7-glucoside 14157911 Click to see COC1=C(C=C2C(=C1O)C(=O)C(=C(O2)C3=CC(=C(C=C3)O)O)O)OC4C(C(C(C(O4)CO)O)O)O 494.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
Patulitrin 5320435 Click to see COC1=C(C=C2C(=C1O)C(=O)C(=C(O2)C3=CC(=C(C=C3)O)O)O)OC4C(C(C(C(O4)CO)O)O)O 494.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
Quercetagetin 7-glucoside 12314844 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O)O)O 480.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
Quercetagitrin 5320826 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O)O)O 480.40 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 3-O-methylated flavonoids
3-Methoxyluteolin 5280681 Click to see COC1=C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O 316.26 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
5,6,7,4'-Tetrahydroxy-3-methoxyflavone 11834044 Click to see COC1=C(OC2=C(C1=O)C(=C(C(=C2)O)O)O)C3=CC=C(C=C3)O 316.26 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
Batatifolin 5320181 Click to see COC1=C(C=CC(=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O 316.26 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 6-O-methylated flavonoids
Axillarin 5281603 Click to see COC1=C(C2=C(C=C1O)OC(=C(C2=O)OC)C3=CC(=C(C=C3)O)O)O 346.30 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
5,6,4'-Trihydroxy-3,7-dimethoxyflavone 13983730 Click to see COC1=C(C(=C2C(=C1)OC(=C(C2=O)OC)C3=CC=C(C=C3)O)O)O 330.29 unknown https://doi.org/10.1016/S0031-9422(00)83809-1
Tomentin 148856 Click to see COC1=C(C(=C2C(=C1)OC(=C(C2=O)OC)C3=CC(=C(C=C3)O)O)O)O 346.30 unknown https://doi.org/10.1016/S0031-9422(00)83809-1

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