Details Top

Internal ID UUID644025bf19ca3907157048
Scientific name Crinum stuhlmannii
Authority Baker
First published in Fl. Trop. Afr. 7: 578 (1898)

Ethnobotanical Use Top

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General Uses Top

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Properties relevant to use:
Crinum stuhlmannii (Baker) is a perennial herb whose bulbs and leaves have been examined for their alkaloid composition. Phytochemical studies have documented the presence of a suite of amaryllidaceae‑type alkaloids, notably lycorine, crinine and related nor‑ and O‑acetyl derivatives. These compounds are stable under acidic conditions, exhibit characteristic UV absorbance near 290 nm, and possess molecular weights that facilitate detection by HPLC‑UV and LC‑MS. Laboratory extracts are prepared as dry powders or as purified isolates and are employed as reference standards in chromatographic method validation and in the study of alkaloid biosynthetic pathways across the Amaryllidaceae. The plant’s relatively high alkaloid yield (reported in the range of 0.3–0.8 % dry weight in bulbs) makes it a practical source for analytical standards without the need for extensive fractionation.

Standards and regulation:
Alkaloid extracts intended for use as certified reference materials are produced in accordance with ISO 17034 (general requirements for reference material producers) and are supplied with documented uncertainty measurements. Analytical laboratories that employ these standards follow ISO/IEC 17025 (general requirements for the competence of testing and calibration laboratories) to ensure data traceability and method validation. When the extracts are used in the European Union for research purposes, the relevant REACH regulation (EC No 1907/2006) applies to the handling of chemical substances, although no specific occupational exposure limits have been established for Crinum‑derived alkaloids.

Sustainability and sourcing:
Crinum stuhlmannii occurs naturally along the East African coast and is presently not listed in the CITES appendices. Wild populations are scattered and generally limited, prompting research programs to source material from ex situ cultivated plants to reduce pressure on natural habitats. Propagation by seed or bulb division is feasible under controlled greenhouse conditions, and sustainable harvesting protocols—such as removing only a fraction of the bulb biomass—have been recommended in regional conservation guidelines. Documentation of provenance and cultivation history is increasingly required by funding agencies to demonstrate compliance with biodiversity conservation policies.

Synonyms Top

No known synonyms.

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Name Authority First published in
Crinum stuhlmannii subsp. delagoense (I.Verd.) Kwembeya & Nordal Kirkia 18: 162 (2007)
Crinum stuhlmannii subsp. stuhlmannii Unknown

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • East Tropical Africa
      • Kenya
      • Tanzania
    • Northeast Tropical Africa
      • Somalia
    • South Tropical Africa
      • Mozambique
      • Zimbabwe
    • Southern Africa
      • Botswana
      • Kwazulu-Natal
      • Northern Provinces

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000764697
Tropicos 1201799
KEW urn:lsid:ipni.org:names:64076-1
The Plant List kew-303600
Open Tree Of Life 965404
NCBI Taxonomy 414790
IPNI 64076-1
iNaturalist 583009
GBIF 2853683
EOL 1087183
CMAUP NPO20070

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Antileishmanial Activity of Clinanthus milagroanthus S. Leiva & Meerow (Amaryllidaceae) Collected in Peru Soto-Vásquez MR, Alvarado-García PA, Osorio EH, Tallini LR, Bastida J Plants (Basel) 10-Jan-2023
PMCID:PMC9866881
doi:10.3390/plants12020322
PMID:36679035
The anti‐Trypanosoma activities of medicinal plants: A systematic review of the literature Nekoei S, Khamesipour F, Habtemariam S, de Souza W, Mohammadi Pour P, Hosseini SR Vet Med Sci 29-Aug-2022
PMCID:PMC9677405
doi:10.1002/vms3.912
PMID:36037401
Amaryllidaceae alkaloids with anti-Trypanosoma cruzi activity Martinez-Peinado N, Cortes-Serra N, Torras-Claveria L, Pinazo MJ, Gascon J, Bastida J, Alonso-Padilla J Parasit Vectors 10-Jun-2020
PMCID:PMC7288428
doi:10.1186/s13071-020-04171-6
PMID:32522289
Ethnobotanical survey in Canhane village, district of Massingir, Mozambique: medicinal plants and traditional knowledge Ribeiro A, Romeiras MM, Tavares J, Faria MT J Ethnobiol Ethnomed 03-Dec-2010
PMCID:PMC3016261
doi:10.1186/1746-4269-6-33
PMID:21129187
Alkaloids from Crinum stuhlmannii. Machocho A, Chhabra SC, Viladomat F, Codina C, Bastida J Planta Med 01-Oct-1998
doi:10.1055/S-2006-957554
PMID:9810280

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Amaryllidaceae alkaloids / Crinine- and Haemanthamine-type amaryllidaceae alkaloids
(+)-Crinamine 118701061 Click to see 301.34 unknown https://doi.org/10.1055/S-2006-957554
(1R,13S,15R,18R)-9,15-dimethoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-18-ol 92211489 Click to see 331.40 unknown https://doi.org/10.1055/S-2006-957554
(1S,13R,15R,18S)-15-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-18-ol 42579248 Click to see 301.34 unknown https://doi.org/10.1055/S-2006-957554
(1S,13R,15R,18S)-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraene-15,18-diol 162950864 Click to see 287.31 unknown https://doi.org/10.1055/S-2006-957554
(1S,13S,15R)-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-15-ol 100929441 Click to see C1CN2CC3=CC4=C(C=C3C15C2CC(C=C5)O)OCO4 271.31 unknown https://doi.org/10.1055/S-2006-957554
(3alpha,11S)-1,2-Didehydro-3,7-dimethoxycrinan-11-ol 25092366 Click to see 331.40 unknown https://doi.org/10.1055/S-2006-957554
1,2-Didehydrocrinan-3-ol 101727 Click to see C1CN2CC3=CC4=C(C=C3C15C2CC(C=C5)O)OCO4 271.31 unknown https://doi.org/10.1055/S-2006-957554
Crinamine 500027 Click to see COC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O 301.34 unknown https://doi.org/10.1055/S-2006-957554
Crinan-12-ol, 1,2-didehydro-3alpha,7-dimethoxy- 494154 Click to see 331.40 unknown https://doi.org/10.1055/S-2006-957554
Crinine 398937 Click to see 271.31 unknown https://doi.org/10.1055/S-2006-957554
Hamayne 443670 Click to see 287.31 unknown https://doi.org/10.1055/S-2006-957554
Vittatine, 11-hydroxy- 602595 Click to see 287.31 unknown https://doi.org/10.1055/S-2006-957554
> Alkaloids and derivatives / Amaryllidaceae alkaloids / Lycorine-type amaryllidaceae alkaloids
Lycorine 72378 Click to see 287.31 unknown https://doi.org/10.1055/S-2006-957554
> Hydrocarbons / Unsaturated hydrocarbons / Enynes
(3E,5Z)-1,3,5-Tridecatriene-7,9,11-triyne 5322029 Click to see CC#CC#CC#CC=CC=CC=C 166.22 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans
Sesamin 72307 Click to see C1C2C(COC2C3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6 354.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acid esters
[(Z)-5-[[(2E,4E,6E)-7-thiophen-2-ylhepta-2,4,6-trienoyl]amino]pent-2-enyl] 3-methylbutanoate 72696081 Click to see CC(C)CC(=O)OCC=CCCNC(=O)C=CC=CC=CC1=CC=CS1 373.50 unknown via CMAUP database
Docosanoic acid, pentyl ester 22608915 Click to see 410.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty amides / N-acyl amines
(2E,4E,6E)-N-Isobutyl-7-(2-Thienyl)-2,4,6-Heptatrienamide 73349612 Click to see 261.40 unknown via CMAUP database
(2E,4E,6E)-N-Isopentyl-7-(2-Thienyl)-2,4,6-Heptatrienamide 72696080 Click to see CC(C)CCNC(=O)C=CC=CC=CC1=CC=CS1 275.40 unknown via CMAUP database
(2E,4E,8Z)-N-(2-methylpropyl)tetradeca-2,4,8-trienamide 73355665 Click to see 277.40 unknown via CMAUP database
(2E,4E)-N-isobutylundeca-2,4-dien-8,10-diynamide 5373537 Click to see 229.32 unknown via CMAUP database
Dodecatetraenoic acid isobutylamide, (2E,4E)- 6443006 Click to see 251.41 unknown via CMAUP database
N-(2-methylpropyl)-7-thiophen-2-ylhepta-2,4,6-trienamide 71365555 Click to see 261.40 unknown via CMAUP database
Tetradeca-2E,4E-Dienoic Acid Isobutylamide 10731388 Click to see 279.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Acyclic diterpenoids
Hexadeca-2,6,10,14-tetraen-1-ol, 3,7,11,16-tetramethyl- 5365865 Click to see 290.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Alpha-Amyrin 73170 Click to see 426.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown via CMAUP database
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Phenylketones / Alkyl-phenylketones
1-(5-Acetyl-2-methoxy-phenyl)-3-methyl-butan-1-one 3009228 Click to see 234.29 unknown via CMAUP database
> Organoheterocyclic compounds / Piperidines / N-acylpiperidines
(2E,4E,8Z)-1-Piperidino-2,4,8-tetradecatriene-1-one 11173777 Click to see CCCCCC=CCCC=CC=CC(=O)N1CCCCC1 289.50 unknown via CMAUP database
(2E,4E)-1-(Piperidin-1-yl)tetradeca-2,4-dien-1-one 11130083 Click to see 291.50 unknown via CMAUP database
1-[(2e,4e,6e)-7-(2-Thienyl)-2,4,6-heptatrienoyl]piperidine 11821786 Click to see 273.40 unknown via CMAUP database
> Organoheterocyclic compounds / Pyridines and derivatives / Hydropyridines / Tetrahydropyridines
(2E,4E,6E)-1-(3,4-dihydro-2H-pyridin-1-yl)-7-thiophen-2-ylhepta-2,4,6-trien-1-one 73346583 Click to see C1CC=CN(C1)C(=O)C=CC=CC=CC2=CC=CS2 271.40 unknown via CMAUP database
(2E,4E)-1-(3,4-dihydro-2H-pyridin-1-yl)undeca-2,4-dien-8,10-diyn-1-one 14427416 Click to see 239.31 unknown via CMAUP database
> Organoheterocyclic compounds / Quinolines and derivatives / Benzoquinolines / Phenanthridines and derivatives
(1|A,2|A)-crinan-1,2-diol 399199 Click to see C1CC2C3(CCN2CC4=CC5=C(C=C43)OCO5)C(C1O)O 289.33 unknown https://doi.org/10.1055/S-2006-957554
(1S,13S,16R,17S)-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9-triene-16,17-diol 163084523 Click to see C1CC2C3(CCN2CC4=CC5=C(C=C43)OCO5)C(C1O)O 289.33 unknown https://doi.org/10.1055/S-2006-957554
5,7-Dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9-triene-16,17-diol 74952092 Click to see 289.33 unknown https://doi.org/10.1055/S-2006-957554
Kirkine 399198 Click to see COC1=C(C=C2CN3CCC4=CCC(C(C43)C2=C1)O)O 273.33 unknown https://doi.org/10.1055/S-2006-957554
Norpluviine 12313583 Click to see COC1=C(C=C2CN3CCC4=CCC(C(C43)C2=C1)O)O 273.33 unknown https://doi.org/10.1055/S-2006-957554
Norpluvine 615152 Click to see COC1=C(C=C2CN3CCC4=CCC(C(C43)C2=C1)O)O 273.33 unknown https://doi.org/10.1055/S-2006-957554
> Phenylpropanoids and polyketides / 2-arylbenzofuran flavonoids
[(2R,3S)-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-5-[(E)-3-oxoprop-1-enyl]-2,3-dihydro-1-benzofuran-3-yl]methyl 3-methylbutanoate 72696082 Click to see CC(C)CC(=O)OCC1C(OC2=C1C=C(C=C2OC)C=CC=O)C3=CC(=C(C=C3)O)OC 440.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
5-Hydroxy-6,7,3',4'-Tetramethoxyflavone 152430 Click to see 358.30 unknown via CMAUP database
Umuhengerin 73648 Click to see COC1=CC(=CC(=C1OC)OC)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)O 388.40 unknown via CMAUP database

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