Zyzzyanone B

Details

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Internal ID 8fed1f95-dea7-43f9-9a91-6ab894958ad0
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyrroloindoles
IUPAC Name 3-(4-hydroxyphenyl)-5-[2-(methylamino)ethyl]-1,7-dihydropyrrolo[3,2-f]indole-4,8-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C19H17N3O3/c1-20-7-6-11-8-21-16-14(11)18(24)15-13(9-22-17(15)19(16)25)10-2-4-12(23)5-3-10/h2-5,8-9,20-23H,6-7H2,1H3
InChI Key MVUIVMXYMJJTCM-UHFFFAOYSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C19H17N3O3
Molecular Weight 335.40 g/mol
Exact Mass 335.12699141 g/mol
Topological Polar Surface Area (TPSA) 98.00 Ų
XlogP 2.20

Synonyms

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3-(4-hydroxyphenyl)-5-(2-(methylamino)ethyl)-1,7-dihydropyrrolo(3,2-f)indole-4,8-dione
3-(4-hydroxyphenyl)-5-[2-(methylamino)ethyl]-1,7-dihydropyrrolo[3,2-f]indole-4,8-dione
2-(3-(4-hydroxyphenyl)-4,8-dioxo-1,7-dihydropyrrolo(3,2-f)indol-5-yl)ethyl-methylazanium
RefChem:196309
866363-59-9
CHEMBL1162275

2D Structure

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2D Structure of Zyzzyanone B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.55% 98.95%
CHEMBL255 P29275 Adenosine A2b receptor 92.96% 98.59%
CHEMBL242 Q92731 Estrogen receptor beta 92.31% 98.35%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.17% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.69% 91.11%
CHEMBL3038469 P24941 CDK2/Cyclin A 90.27% 91.38%
CHEMBL2345 P51812 Ribosomal protein S6 kinase alpha 3 90.14% 95.64%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 88.60% 91.79%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 87.03% 92.88%
CHEMBL4630 O14757 Serine/threonine-protein kinase Chk1 86.38% 97.03%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 85.03% 93.10%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.62% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.72% 86.33%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.57% 94.00%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 83.38% 95.83%
CHEMBL3401 O75469 Pregnane X receptor 83.34% 94.73%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 83.06% 83.10%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 82.21% 95.17%
CHEMBL2093869 P05106 Integrin alpha-IIb/beta-3 82.13% 95.42%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.10% 95.56%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.89% 94.33%
CHEMBL3922 P50579 Methionine aminopeptidase 2 81.85% 97.28%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.78% 90.71%
CHEMBL1937 Q92769 Histone deacetylase 2 81.75% 94.75%
CHEMBL4578 Q14680 Maternal embryonic leucine zipper kinase 81.16% 81.58%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.49% 99.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11493734
LOTUS LTS0041633
wikiData Q105173317