Yanucamide A

Details

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Internal ID 8990eb94-1844-4339-a407-2691fba50657
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (2S,5R,16S)-5-benzyl-4,13,13-trimethyl-12-pent-4-ynyl-2,16-di(propan-2-yl)-1,11-dioxa-4,7,15-triazacycloheptadecane-3,6,10,14,17-pentone
SMILES (Canonical) CC(C)C1C(=O)OC(C(=O)N(C(C(=O)NCCC(=O)OC(C(C(=O)N1)(C)C)CCCC#C)CC2=CC=CC=C2)C)C(C)C
SMILES (Isomeric) CC(C)[C@H]1C(=O)O[C@H](C(=O)N([C@@H](C(=O)NCCC(=O)OC(C(C(=O)N1)(C)C)CCCC#C)CC2=CC=CC=C2)C)C(C)C
InChI InChI=1S/C33H47N3O7/c1-9-10-12-17-25-33(6,7)32(41)35-27(21(2)3)31(40)43-28(22(4)5)30(39)36(8)24(20-23-15-13-11-14-16-23)29(38)34-19-18-26(37)42-25/h1,11,13-16,21-22,24-25,27-28H,10,12,17-20H2,2-8H3,(H,34,38)(H,35,41)/t24-,25?,27+,28+/m1/s1
InChI Key UJLAUQGSVXILEB-AEDGQBGKSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C33H47N3O7
Molecular Weight 597.70 g/mol
Exact Mass 597.34140085 g/mol
Topological Polar Surface Area (TPSA) 131.00 Ų
XlogP 4.90

Synonyms

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CHEMBL510997
SCHEMBL16431504
DTXSID001334709
(2S,5R,16S)-5-benzyl-4,13,13-trimethyl-12-pent-4-ynyl-2,16-di(propan-2-yl)-1,11-dioxa-4,7,15-triazacycloheptadecane-3,6,10,14,17-pentone

2D Structure

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2D Structure of Yanucamide A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.62% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.27% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 96.92% 90.17%
CHEMBL4072 P07858 Cathepsin B 95.69% 93.67%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.56% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.98% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.03% 85.14%
CHEMBL5103 Q969S8 Histone deacetylase 10 89.56% 90.08%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 89.21% 93.00%
CHEMBL3837 P07711 Cathepsin L 88.01% 96.61%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.82% 97.25%
CHEMBL3310 Q96DB2 Histone deacetylase 11 86.48% 88.56%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 86.40% 82.38%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.46% 99.23%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 84.92% 89.67%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.81% 86.33%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 84.25% 97.64%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 84.21% 85.94%
CHEMBL1949 P62937 Cyclophilin A 82.92% 98.57%
CHEMBL3227 P41594 Metabotropic glutamate receptor 5 82.85% 96.42%
CHEMBL255 P29275 Adenosine A2b receptor 82.59% 98.59%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.54% 95.50%
CHEMBL2996 Q05655 Protein kinase C delta 81.47% 97.79%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 80.71% 94.45%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 21668737
LOTUS LTS0127848
wikiData Q77521792