Yangpumicin A

Details

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Internal ID df836278-d179-42f4-a06e-4419014d857e
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Hydroxysteroids > 6-hydroxysteroids
IUPAC Name (1S,17S,24R,26R)-4,11,24-trihydroxy-26-[(1R)-1-hydroxyethyl]-25-oxa-16-azahexacyclo[15.7.2.01,26.02,15.05,14.07,12]hexacosa-2,4,7(12),8,10,14,20-heptaen-18,22-diyne-6,13-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H17NO7/c1-12(28)25-17-9-4-2-3-5-10-18(31)26(25,34-25)14-11-16(30)20-21(22(14)27-17)24(33)19-13(23(20)32)7-6-8-15(19)29/h2-3,6-8,11-12,17-18,27-31H,1H3/t12-,17+,18-,25+,26+/m1/s1
InChI Key OBUHDEKWYQCPLP-DWOUCKERSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C26H17NO7
Molecular Weight 455.40 g/mol
Exact Mass 455.10050188 g/mol
Topological Polar Surface Area (TPSA) 140.00 Ų
XlogP 2.30

Synonyms

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(1S,17S,24R,26R)-4,11,24-trihydroxy-26-((1R)-1-hydroxyethyl)-25-oxa-16-azahexacyclo(15.7.2.01,26.02,15.05,14.07,12)hexacosa-2,4,7(12),8,10,14,20-heptaen-18,22-diyne-6,13-dione
(1S,17S,24R,26R)-4,11,24-trihydroxy-26-[(1R)-1-hydroxyethyl]-25-oxa-16-azahexacyclo[15.7.2.01,26.02,15.05,14.07,12]hexacosa-2,4,7(12),8,10,14,20-heptaen-18,22-diyne-6,13-dione
RefChem:195594
SCHEMBL30747812
CHEBI:216781

2D Structure

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2D Structure of Yangpumicin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.74% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.44% 91.11%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 96.48% 96.38%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.06% 95.56%
CHEMBL3401 O75469 Pregnane X receptor 95.35% 94.73%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 94.82% 99.15%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.10% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.77% 89.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 91.72% 93.03%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.37% 99.23%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 90.85% 93.40%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 88.78% 90.71%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 88.55% 92.88%
CHEMBL1937 Q92769 Histone deacetylase 2 88.35% 94.75%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.58% 85.14%
CHEMBL226 P30542 Adenosine A1 receptor 87.41% 95.93%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 87.21% 96.09%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.24% 82.69%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 85.83% 85.11%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 85.31% 100.00%
CHEMBL2179 P04062 Beta-glucocerebrosidase 85.15% 85.31%
CHEMBL2535 P11166 Glucose transporter 84.02% 98.75%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.46% 97.09%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.18% 97.14%
CHEMBL4208 P20618 Proteasome component C5 81.05% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139591107
LOTUS LTS0204176
wikiData Q105189174