Yaequinolone B_120182

Details

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Internal ID 71aaa507-7cc1-4783-a78d-35c1f751a5d4
Taxonomy Organoheterocyclic compounds > Quinolines and derivatives > Phenylquinolines
IUPAC Name (3R,4R)-4,5-dihydroxy-3-methoxy-4-(4-methoxyphenyl)-6-[(E)-3-oxobut-1-enyl]-1,3-dihydroquinolin-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H21NO6/c1-12(23)4-5-13-6-11-16-17(18(13)24)21(26,19(28-3)20(25)22-16)14-7-9-15(27-2)10-8-14/h4-11,19,24,26H,1-3H3,(H,22,25)/b5-4+/t19-,21+/m0/s1
InChI Key XYRSQOXRWJBEIG-PXODQFSGSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H21NO6
Molecular Weight 383.40 g/mol
Exact Mass 383.13688739 g/mol
Topological Polar Surface Area (TPSA) 105.00 Ų
XlogP 1.10

Synonyms

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Yaequinolone B
CHEBI:182194
(3R,4R)-4,5-dihydroxy-3-methoxy-4-(4-methoxyphenyl)-6-[(E)-3-oxobut-1-enyl]-1,3-dihydroquinolin-2-one

2D Structure

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2D Structure of Yaequinolone B_120182

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.28% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.78% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.18% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.85% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.65% 86.33%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 89.05% 96.00%
CHEMBL1937 Q92769 Histone deacetylase 2 88.81% 94.75%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.81% 97.09%
CHEMBL2581 P07339 Cathepsin D 87.45% 98.95%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.84% 95.89%
CHEMBL340 P08684 Cytochrome P450 3A4 83.14% 91.19%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 83.04% 92.88%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.27% 95.50%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.22% 94.00%
CHEMBL4208 P20618 Proteasome component C5 82.08% 90.00%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 81.31% 86.92%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 80.34% 94.08%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 16091464
LOTUS LTS0117960
wikiData Q77521677