Xentrivalpeptide L

Details

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Internal ID ffe29941-243c-4219-a934-05ab84cabafc
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (2S)-3-methyl-N-[(3R,6S,7R,10S,13S,16S,19S)-7-methyl-3-(2-methylpropyl)-2,5,9,12,15,18-hexaoxo-10,13,16-tri(propan-2-yl)-8-oxa-1,4,11,14,17-pentazabicyclo[17.3.0]docosan-6-yl]-2-[(2-phenylacetyl)amino]butanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C43H67N7O9/c1-22(2)20-29-42(57)50-19-15-18-30(50)37(52)46-33(24(5)6)39(54)47-34(25(7)8)40(55)48-35(26(9)10)43(58)59-27(11)36(41(56)44-29)49-38(53)32(23(3)4)45-31(51)21-28-16-13-12-14-17-28/h12-14,16-17,22-27,29-30,32-36H,15,18-21H2,1-11H3,(H,44,56)(H,45,51)(H,46,52)(H,47,54)(H,48,55)(H,49,53)/t27-,29-,30+,32+,33+,34+,35+,36+/m1/s1
InChI Key RSWKXBQPPHRRRM-STDQDTGYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C43H67N7O9
Molecular Weight 826.00 g/mol
Exact Mass 825.50002674 g/mol
Topological Polar Surface Area (TPSA) 221.00 Ų
XlogP 5.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Xentrivalpeptide L

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.87% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.99% 85.14%
CHEMBL333 P08253 Matrix metalloproteinase-2 97.73% 96.31%
CHEMBL221 P23219 Cyclooxygenase-1 95.42% 90.17%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.64% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.09% 96.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 93.87% 90.08%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 90.90% 93.00%
CHEMBL3524 P56524 Histone deacetylase 4 90.03% 92.97%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 89.91% 97.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.02% 97.09%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 88.96% 97.64%
CHEMBL4588 P22894 Matrix metalloproteinase 8 88.01% 94.66%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.60% 95.89%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 87.31% 91.11%
CHEMBL3060 Q9Y345 Glycine transporter 2 85.56% 99.17%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.33% 93.03%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.20% 99.23%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 82.59% 95.83%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 82.54% 90.71%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 82.08% 98.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 81.69% 93.56%
CHEMBL3837 P07711 Cathepsin L 81.46% 96.61%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 81.06% 96.47%
CHEMBL4072 P07858 Cathepsin B 80.48% 93.67%
CHEMBL321 P14780 Matrix metalloproteinase 9 80.34% 92.12%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 80.20% 82.38%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 71619937
LOTUS LTS0161452
wikiData Q77509117