Xentrivalpeptide J

Details

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Internal ID 3b246fab-83bd-46f9-8f7e-ba0c2f43a46b
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (2S)-2-(butanoylamino)-3-methyl-N-[(3R,6S,7R,10S,13S,16S,19S)-7-methyl-3-(2-methylpropyl)-2,5,9,12,15,18-hexaoxo-10,13,16-tri(propan-2-yl)-8-oxa-1,4,11,14,17-pentazabicyclo[17.3.0]docosan-6-yl]butanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C39H67N7O9/c1-13-15-27(47)41-28(20(4)5)34(49)45-32-24(12)55-39(54)31(23(10)11)44-36(51)30(22(8)9)43-35(50)29(21(6)7)42-33(48)26-16-14-17-46(26)38(53)25(18-19(2)3)40-37(32)52/h19-26,28-32H,13-18H2,1-12H3,(H,40,52)(H,41,47)(H,42,48)(H,43,50)(H,44,51)(H,45,49)/t24-,25-,26+,28+,29+,30+,31+,32+/m1/s1
InChI Key JVEDJMVSQSKMIY-PVPSYGHLSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C39H67N7O9
Molecular Weight 778.00 g/mol
Exact Mass 777.50002674 g/mol
Topological Polar Surface Area (TPSA) 221.00 Ų
XlogP 4.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Xentrivalpeptide J

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.74% 98.95%
CHEMBL333 P08253 Matrix metalloproteinase-2 99.07% 96.31%
CHEMBL5103 Q969S8 Histone deacetylase 10 97.58% 90.08%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.21% 85.14%
CHEMBL4588 P22894 Matrix metalloproteinase 8 95.88% 94.66%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.67% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.22% 96.09%
CHEMBL332 P03956 Matrix metalloproteinase-1 93.09% 94.50%
CHEMBL3468 P55210 Caspase-7 92.60% 95.68%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.96% 97.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.72% 99.23%
CHEMBL4072 P07858 Cathepsin B 91.16% 93.67%
CHEMBL3359 P21462 Formyl peptide receptor 1 90.54% 93.56%
CHEMBL255 P29275 Adenosine A2b receptor 90.14% 98.59%
CHEMBL3837 P07711 Cathepsin L 90.01% 96.61%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.16% 91.11%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 89.04% 96.11%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 88.89% 82.38%
CHEMBL2413 P32246 C-C chemokine receptor type 1 88.71% 89.50%
CHEMBL3524 P56524 Histone deacetylase 4 88.52% 92.97%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.69% 90.71%
CHEMBL321 P14780 Matrix metalloproteinase 9 87.59% 92.12%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 87.57% 95.00%
CHEMBL3691 Q13822 Autotaxin 87.47% 96.39%
CHEMBL2094135 Q96BI3 Gamma-secretase 87.46% 98.05%
CHEMBL3060 Q9Y345 Glycine transporter 2 87.39% 99.17%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.39% 94.45%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.86% 97.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.53% 95.56%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 85.29% 96.47%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 85.22% 98.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.14% 93.03%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 84.66% 96.90%
CHEMBL283 P08254 Matrix metalloproteinase 3 83.61% 97.29%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.18% 95.89%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 82.99% 97.50%
CHEMBL4801 P29466 Caspase-1 82.53% 96.85%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 82.39% 97.64%
CHEMBL4073 P09237 Matrix metalloproteinase 7 82.27% 97.56%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.26% 93.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.01% 89.00%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 81.66% 95.50%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 81.01% 95.83%
CHEMBL1075317 P61964 WD repeat-containing protein 5 80.88% 96.33%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 80.78% 94.33%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 80.47% 96.38%
CHEMBL221 P23219 Cyclooxygenase-1 80.20% 90.17%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 71619935
LOTUS LTS0012066
wikiData Q77368806