Wewakazole

Details

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Internal ID 26f126f4-701d-4413-bf85-78161fb119b5
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name (4S,11S,17S,20S,27S,33S,39S,45S)-4,11-dibenzyl-20-[(2S)-butan-2-yl]-27,48-dimethyl-45-propan-2-yl-6,22,47-trioxa-3,10,13,19,26,29,35,41,44,49,50,51-dodecazaheptacyclo[44.2.1.15,8.121,24.013,17.029,33.035,39]henpentaconta-1(48),5(51),7,21(50),23,46(49)-hexaene-2,9,12,18,25,28,34,40,43-nonone
SMILES (Canonical) CCC(C)C1C2=NC(=CO2)C(=O)NC(C(=O)N3CCCC3C(=O)N4CCCC4C(=O)NCC(=O)NC(C5=NC(=C(O5)C)C(=O)NC(C6=NC(=CO6)C(=O)NC(C(=O)N7CCCC7C(=O)N1)CC8=CC=CC=C8)CC9=CC=CC=C9)C(C)C)C
SMILES (Isomeric) CC[C@H](C)[C@H]1C2=NC(=CO2)C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N4CCC[C@H]4C(=O)NCC(=O)N[C@H](C5=NC(=C(O5)C)C(=O)N[C@H](C6=NC(=CO6)C(=O)N[C@H](C(=O)N7CCC[C@H]7C(=O)N1)CC8=CC=CC=C8)CC9=CC=CC=C9)C(C)C)C
InChI InChI=1S/C59H72N12O12/c1-7-33(4)47-55-65-40(31-82-55)49(73)61-34(5)57(78)71-26-16-23-44(71)59(80)70-25-14-21-42(70)51(75)60-29-45(72)66-46(32(2)3)56-68-48(35(6)83-56)53(77)62-38(27-36-17-10-8-11-18-36)54-64-41(30-81-54)50(74)63-39(28-37-19-12-9-13-20-37)58(79)69-24-15-22-43(69)52(76)67-47/h8-13,17-20,30-34,38-39,42-44,46-47H,7,14-16,21-29H2,1-6H3,(H,60,75)(H,61,73)(H,62,77)(H,63,74)(H,66,72)(H,67,76)/t33-,34-,38-,39-,42-,43-,44-,46-,47-/m0/s1
InChI Key LRFQMOZAQWOOPZ-IBFZZIGPSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C59H72N12O12
Molecular Weight 1141.30 g/mol
Exact Mass 1140.53926578 g/mol
Topological Polar Surface Area (TPSA) 314.00 Ų
XlogP 4.70

Synonyms

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DTXSID801046508
RefChem:194821
DTXCID301528333
(12S,32S,82Z,122S,172Z,212Z,5S,9S,14S,18S,22S)-14,18-dibenzyl-9-((S)-sec-butyl)-22-isopropyl-215,5-dimethyl-6,10,15,19,23,26-hexaaza-8,17,21(4,2)-trioxazola-1(1,2),3,12(2,1)-tripyrrolidinacycloheptacosaphane-2,4,7,11,13,16,20,24,27-nonaone
(4S,11S,17S,20S,27S,33S,39S,45S)-4,11-dibenzyl-20-((2S)-butan-2-yl)-27,48-dimethyl-45-propan-2-yl-6,22,47-trioxa-3,10,13,19,26,29,35,41,44,49,50,51-dodecazaheptacyclo(44.2.1.15,8.121,24.013,17.029,33.035,39)henpentaconta-1(48),5(51),7,21(50),23,46(49)-hexaene-2,9,12,18,25,28,34,40,43-nonone
494798-69-5
CHEMBL1669190
CHEBI:70163
Q27138505

2D Structure

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2D Structure of Wewakazole

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.81% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 95.77% 85.14%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 95.74% 97.64%
CHEMBL4447 Q9Y337 Kallikrein 5 93.71% 87.50%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.42% 86.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 92.44% 93.03%
CHEMBL3524 P56524 Histone deacetylase 4 92.14% 92.97%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 92.01% 93.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.81% 97.09%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 91.55% 82.38%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 91.18% 91.71%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.88% 96.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.48% 99.23%
CHEMBL5203 P33316 dUTP pyrophosphatase 89.35% 99.18%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.68% 95.56%
CHEMBL1801 P00747 Plasminogen 88.17% 92.44%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 86.96% 95.50%
CHEMBL5103 Q969S8 Histone deacetylase 10 86.18% 90.08%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.89% 94.00%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 85.04% 96.39%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.72% 95.89%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.29% 90.71%
CHEMBL2443 P49862 Kallikrein 7 82.80% 94.00%
CHEMBL3401 O75469 Pregnane X receptor 82.69% 94.73%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 82.45% 95.34%
CHEMBL2189110 Q15910 Histone-lysine N-methyltransferase EZH2 82.19% 97.50%
CHEMBL6175 Q9H3R0 Lysine-specific demethylase 4C 81.82% 96.69%
CHEMBL4071 P08311 Cathepsin G 81.69% 94.64%
CHEMBL2243 O00519 Anandamide amidohydrolase 81.27% 97.53%
CHEMBL2916 O14746 Telomerase reverse transcriptase 80.72% 90.00%
CHEMBL221 P23219 Cyclooxygenase-1 80.42% 90.17%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 21578002
LOTUS LTS0134260
wikiData Q27138505