Wewakamide A

Details

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Internal ID 8f10bff3-9363-4706-a5ff-5611df32400c
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3S,6S,9S,12R,13R,16S,19S,22S,25S,28S)-6-benzyl-19-[(2S)-butan-2-yl]-12,13,20,23,25,26-hexamethyl-9,22-bis(2-methylpropyl)-3,16-di(propan-2-yl)-4-oxa-1,7,10,14,17,20,23,26-octazabicyclo[26.3.0]hentriacontane-2,5,8,11,15,18,21,24,27-nonone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C53H86N8O10/c1-17-33(10)43-48(65)57-42(31(6)7)47(64)54-35(12)34(11)45(62)55-38(26-29(2)3)46(63)56-39(28-37-22-19-18-20-23-37)53(70)71-44(32(8)9)52(69)61-25-21-24-40(61)50(67)58(14)36(13)49(66)59(15)41(27-30(4)5)51(68)60(43)16/h18-20,22-23,29-36,38-44H,17,21,24-28H2,1-16H3,(H,54,64)(H,55,62)(H,56,63)(H,57,65)/t33-,34+,35+,36-,38-,39-,40-,41-,42-,43-,44-/m0/s1
InChI Key QGVOFCJSCWSNCO-POWBWRITSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C53H86N8O10
Molecular Weight 995.30 g/mol
Exact Mass 994.64669097 g/mol
Topological Polar Surface Area (TPSA) 224.00 Ų
XlogP 7.10

Synonyms

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DTXSID701102391

2D Structure

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2D Structure of Wewakamide A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.86% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.29% 96.09%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 96.47% 97.64%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 95.35% 82.38%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.15% 97.25%
CHEMBL333 P08253 Matrix metalloproteinase-2 95.06% 96.31%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.47% 95.56%
CHEMBL1949 P62937 Cyclophilin A 94.21% 98.57%
CHEMBL1978 P11511 Cytochrome P450 19A1 93.87% 91.76%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.73% 85.14%
CHEMBL5103 Q969S8 Histone deacetylase 10 93.63% 90.08%
CHEMBL221 P23219 Cyclooxygenase-1 90.73% 90.17%
CHEMBL1902 P62942 FK506-binding protein 1A 90.73% 97.05%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 89.41% 97.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.05% 86.33%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 87.18% 94.45%
CHEMBL5203 P33316 dUTP pyrophosphatase 86.86% 99.18%
CHEMBL3837 P07711 Cathepsin L 86.70% 96.61%
CHEMBL3359 P21462 Formyl peptide receptor 1 86.02% 93.56%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 85.79% 93.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.35% 95.89%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 83.26% 95.00%
CHEMBL255 P29275 Adenosine A2b receptor 83.05% 98.59%
CHEMBL4072 P07858 Cathepsin B 82.98% 93.67%
CHEMBL4616 Q92847 Ghrelin receptor 82.40% 92.00%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 81.98% 98.33%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.44% 99.23%
CHEMBL3401 O75469 Pregnane X receptor 80.49% 94.73%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139586107
LOTUS LTS0074349
wikiData Q77498977