Wailupemycin B

Details

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Internal ID 893f632f-208d-41f2-ad1a-4a4aa9fb9304
Taxonomy Organoheterocyclic compounds > Oxepanes
IUPAC Name (1R,3R,6R,8R)-3-hydroxy-8-[(4-methoxy-6-oxopyran-2-yl)methyl]-1-phenyl-9,10-dioxatricyclo[4.3.1.03,8]decan-4-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H20O7/c1-25-14-7-15(26-18(23)9-14)10-19-11-16-8-17(22)20(19,24)12-21(27-16,28-19)13-5-3-2-4-6-13/h2-7,9,16,24H,8,10-12H2,1H3/t16-,19-,20-,21+/m0/s1
InChI Key AMKBZANFPJYUOK-LRGNLBRXSA-N
Popularity 6 references in papers

Physical and Chemical Properties

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Molecular Formula C21H20O7
Molecular Weight 384.40 g/mol
Exact Mass 384.12090297 g/mol
Topological Polar Surface Area (TPSA) 91.30 Ų
XlogP 0.80

Synonyms

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SCHEMBL17867269
(1R,3R,6R,8R)-3-Hydroxy-8-[(4-methoxy-6-oxopyran-2-yl)methyl]-1-phenyl-9,10-dioxatricyclo[4.3.1.03,8]decan-4-one

2D Structure

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2D Structure of Wailupemycin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.76% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 98.38% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.02% 96.09%
CHEMBL2581 P07339 Cathepsin D 94.65% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.31% 86.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.08% 95.56%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 90.79% 94.62%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 90.43% 94.08%
CHEMBL216 P11229 Muscarinic acetylcholine receptor M1 89.24% 94.23%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.12% 92.62%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.10% 94.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 85.83% 95.50%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.44% 99.23%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 84.17% 91.07%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.84% 97.09%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 82.63% 96.95%
CHEMBL4208 P20618 Proteasome component C5 82.51% 90.00%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 81.33% 99.15%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.22% 99.17%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10548038
LOTUS LTS0206016
wikiData Q77565576